MX9701076A - Method for diagnosing a predisposition for breast and ovarian cancer. - Google Patents

Method for diagnosing a predisposition for breast and ovarian cancer.

Info

Publication number
MX9701076A
MX9701076A MX9701076A MX9701076A MX9701076A MX 9701076 A MX9701076 A MX 9701076A MX 9701076 A MX9701076 A MX 9701076A MX 9701076 A MX9701076 A MX 9701076A MX 9701076 A MX9701076 A MX 9701076A
Authority
MX
Mexico
Prior art keywords
ovarian cancer
breast
relates
human
gene
Prior art date
Application number
MX9701076A
Other languages
Spanish (es)
Inventor
Mark H Skolnick
David E Goldgar
Jeff Swenson
Alexander Kamb
Keith D Harshman
Donna M Shattuck-Eidens
Sean V Tavtigian
Roger W Wiseman
P Andrew Futreal
Original Assignee
Myriad Genetics Inc
Univ Utah Res Founda
Tion
Estados Unidos De America Repr
Tado Por El Secretario Del Dep
Mento De Salud Y Servicios Hum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/487,002 external-priority patent/US5710001A/en
Priority claimed from US08/483,554 external-priority patent/US5747282A/en
Application filed by Myriad Genetics Inc, Univ Utah Res Founda, Tion, Estados Unidos De America Repr, Tado Por El Secretario Del Dep, Mento De Salud Y Servicios Hum filed Critical Myriad Genetics Inc
Priority claimed from PCT/US1995/010220 external-priority patent/WO1996005308A1/en
Publication of MX9701076A publication Critical patent/MX9701076A/en

Links

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of which cause susceptibility to cancer, in particular breast and ovarian cancer. More specifically, the invention relates to germline mutations in the BRCA1 gene and their use in the diagnosis of predisposition to breast and ovarian cancer. The present invention further relates to somatic mutations in the BRCA1 gene in human breast and ovarian cancer and their use in the diagnosis and prognosis of human breast and ovarian cancer. Additionally, the invention relates to somatic mutations in the BRCA1 gene in other human cancers and their use in the diagnosis and prognosis of human cancers. The invention also relates to the therapy of human cancers which have a mutation in the BRCA1 gene, including gene therapy, protein replacement therapy and protein mimetics. The invention further relates to the screening of drugs for cancer therapy. Finally, the invention relates to the screening of the BRCA1 gene for mutations, which are useful for diagnosing the predisposition to breast and ovarian cancer.
MX9701076A 1994-09-02 1995-08-11 Method for diagnosing a predisposition for breast and ovarian cancer. MX9701076A (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US30026694A 1994-09-02 1994-09-02
US30810494A 1994-09-16 1994-09-16
US34882494A 1994-11-29 1994-11-29
US40930595A 1995-03-24 1995-03-24
US48801195A 1995-06-07 1995-06-07
US08/487,002 US5710001A (en) 1994-08-12 1995-06-07 17q-linked breast and ovarian cancer susceptibility gene
US08/483,554 US5747282A (en) 1994-08-12 1995-06-07 17Q-linked breast and ovarian cancer susceptibility gene
PCT/US1995/010220 WO1996005308A1 (en) 1994-08-12 1995-08-11 Method for diagnosing a predisposition for breast and ovarian cancer

Publications (1)

Publication Number Publication Date
MX9701076A true MX9701076A (en) 1998-02-28

Family

ID=39165514

Family Applications (2)

Application Number Title Priority Date Filing Date
MX9701076A MX9701076A (en) 1994-09-02 1995-08-11 Method for diagnosing a predisposition for breast and ovarian cancer.
MX9701074A MX9701074A (en) 1994-09-02 1995-08-11 17q-LINKED BREAST AND OVARIAN CANCER SUSCEPTIBILITY GENE.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX9701074A MX9701074A (en) 1994-09-02 1995-08-11 17q-LINKED BREAST AND OVARIAN CANCER SUSCEPTIBILITY GENE.

Country Status (1)

Country Link
MX (2) MX9701076A (en)

Also Published As

Publication number Publication date
MX9701074A (en) 1998-02-28

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