MX9700881A - Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica. - Google Patents
Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica.Info
- Publication number
- MX9700881A MX9700881A MX9700881A MX9700881A MX9700881A MX 9700881 A MX9700881 A MX 9700881A MX 9700881 A MX9700881 A MX 9700881A MX 9700881 A MX9700881 A MX 9700881A MX 9700881 A MX9700881 A MX 9700881A
- Authority
- MX
- Mexico
- Prior art keywords
- cholanes
- pregnanes
- change
- vomeropherin
- hypothalamic function
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invencion se refiere a un método para alterar la funcion hipotalámica en un individuo. Este método comprende administrar nasalmente una vomeroferina humana, por ejemplo un esteroide de pregnano o colano, o una composicion farmacéutica que contenga una vomeroferina, de manera que esta vomeroferina se ligue a un receptor neuroepitelial específico. Se administra el esteroide a los esteroides en la forma de una composicion fermacéutica que contiene uno o más portadores aceptables farmacéuticamente. Otras modalidades de la invencion incluyen composiciones farmacéuticas que contienen los esteroides.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/286,073 US5563131A (en) | 1994-08-04 | 1994-08-04 | Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods |
US08/510,957 US5994333A (en) | 1994-08-04 | 1995-08-03 | Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods |
PCT/US1995/009634 WO1996004296A1 (en) | 1994-08-04 | 1995-08-04 | Pregnanes and cholanes as neurochemical initiators of change in hypothalamic function |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9700881A true MX9700881A (es) | 1997-04-30 |
Family
ID=26963568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9700881A MX9700881A (es) | 1994-08-04 | 1995-08-04 | Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5994333A (es) |
EP (1) | EP0775154A4 (es) |
CN (1) | CN1173181A (es) |
BR (1) | BR9508519A (es) |
CA (1) | CA2196690C (es) |
CZ (1) | CZ32997A3 (es) |
FI (1) | FI970447A (es) |
MX (1) | MX9700881A (es) |
NO (1) | NO311328B1 (es) |
NZ (1) | NZ291056A (es) |
PL (1) | PL318521A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030045514A1 (en) * | 2001-05-03 | 2003-03-06 | Louis Monti | 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors |
US20090075964A1 (en) * | 2007-09-17 | 2009-03-19 | Human Pheromone Sciences, Inc. | Fragrance compositions and other compositions which contain naturally occurring substances found in corals |
DK2278880T3 (da) * | 2008-04-09 | 2012-11-12 | Pherin Pharm Inc | Steroidbehandling af hedeture |
US10322138B2 (en) | 2012-12-28 | 2019-06-18 | Pherin Pharmaceuticals, Inc. | Treatment of depressive disorders |
CN114128658B (zh) * | 2021-11-25 | 2023-03-24 | 中国水产科学研究院黑龙江水产研究所 | 一种用于人工鱼巢的改性椰丝材料的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
EP0701444B1 (en) * | 1993-05-24 | 2010-04-07 | Purdue Pharma Ltd. | Methods and compositions for inducing sleep |
CA2165324A1 (en) * | 1993-06-15 | 1994-12-22 | David L. Berliner | Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods |
DE69333352T2 (de) * | 1993-06-15 | 2004-07-22 | Pherin Corp., Menlo Park | Androstansteroide als neurochemische initiatoren einer veränderung der hypothalamusfunktion beim menschen und verwandte pharmazeutische präparate und verfahren |
-
1995
- 1995-08-03 US US08/510,957 patent/US5994333A/en not_active Expired - Lifetime
- 1995-08-04 EP EP95928215A patent/EP0775154A4/en not_active Ceased
- 1995-08-04 PL PL95318521A patent/PL318521A1/xx unknown
- 1995-08-04 CA CA002196690A patent/CA2196690C/en not_active Expired - Fee Related
- 1995-08-04 BR BR9508519A patent/BR9508519A/pt not_active Application Discontinuation
- 1995-08-04 NZ NZ291056A patent/NZ291056A/en unknown
- 1995-08-04 MX MX9700881A patent/MX9700881A/es active IP Right Grant
- 1995-08-04 CZ CZ97329A patent/CZ32997A3/cs unknown
- 1995-08-04 CN CN95195480A patent/CN1173181A/zh active Pending
-
1997
- 1997-02-03 FI FI970447A patent/FI970447A/fi unknown
- 1997-02-03 NO NO19970472A patent/NO311328B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5994333A (en) | 1999-11-30 |
CA2196690A1 (en) | 1996-02-15 |
NZ291056A (en) | 2001-03-30 |
NO970472L (no) | 1997-04-03 |
FI970447A (fi) | 1997-04-03 |
CA2196690C (en) | 2008-01-08 |
CN1173181A (zh) | 1998-02-11 |
NO970472D0 (no) | 1997-02-03 |
PL318521A1 (en) | 1997-06-23 |
EP0775154A1 (en) | 1997-05-28 |
CZ32997A3 (en) | 1997-09-17 |
FI970447A0 (fi) | 1997-02-03 |
EP0775154A4 (en) | 2001-05-09 |
NO311328B1 (no) | 2001-11-19 |
BR9508519A (pt) | 1998-07-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2223397A1 (en) | Novel nor-pregnanes for inducing hypothalamic effects | |
MD1920F2 (ro) | Compoziţie şi metodă de profilaxie sau frânare a debutului bolii Alzheimer | |
GEP20012530B (en) | Neuroactive Steroids of the Androstane and Pregnane Series | |
EP0711169A4 (en) | ANDROSTANTEROIDS AS A NEUROCHEMICAL INITIATORS OF A CHANGE IN HUMAN HUMAN FUNCTION AND RELATED PHARMACEUTICAL PREPARATIONS AND METHODS | |
CA2258177A1 (en) | 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function | |
AU3963797A (en) | Steroids as neurochemical stimulators of the vno to alleviate symptoms of pms and anxiety | |
HU9503579D0 (en) | Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods | |
MX9700881A (es) | Pregnanos y colanos como indicadores neuroquimicos del cambio en la funcion hipotalamica. | |
EP0924219A3 (en) | Novel estrenes for inducing hypothalamic effects | |
HK1009403A1 (en) | Tnf receptor and steroid hormone dhea in a combined therapy | |
MXPA94000705A (es) | Esteroides de estreno como iniciadores neuroquimicos del cambio en la funcion hipotalamica humana ycomposiciones farmaceuticas y metodos relacionados. | |
CA2248841A1 (en) | Sequential oestrogen/progesterone antagonist combination for hormone replacement therapy | |
BR9816142A (pt) | Esteróides de 19-nor-colano como iniciadores neuroquìmicos de mudança na função hipotalâmica humana | |
TW289730B (en) | Pharmaceutical composition for alleviating the symptoms of psychoses, depression or anxiety comprising androstene steroids | |
IL108155A0 (en) | Pharmaceutical compositions containing 17 alphadihydroequilenin or an ester or salt thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |