MX9605048A - Gonadotropinas con puentes de disulfuros no nativos. - Google Patents
Gonadotropinas con puentes de disulfuros no nativos.Info
- Publication number
- MX9605048A MX9605048A MX9605048A MX9605048A MX9605048A MX 9605048 A MX9605048 A MX 9605048A MX 9605048 A MX9605048 A MX 9605048A MX 9605048 A MX9605048 A MX 9605048A MX 9605048 A MX9605048 A MX 9605048A
- Authority
- MX
- Mexico
- Prior art keywords
- gonadothropines
- disulfide bridges
- non native
- native disulfide
- sub
- Prior art date
Links
- 108010001267 Protein Subunits Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Reproductive Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invencion se refiere a las gonadotropinas que consisten en una subunidad y una subunidad, comprendiendo dichas gonadotropinas puentes de disulfuro no nativos, de preferencia puentes de disulfuro entre subunidades no nativos. Las gonadotropinas de acuerdo con la invencion tienen una estabilidad mejorada. La presente invencion además considera composiciones farmacéuticas que comprenden dichas gonadotropinas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL95202876.9 | 1995-10-24 | ||
EP95202876 | 1995-10-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX9605048A true MX9605048A (es) | 1997-09-30 |
MXPA96005048A MXPA96005048A (es) | 1998-07-03 |
Family
ID=
Also Published As
Publication number | Publication date |
---|---|
EP0785215A1 (en) | 1997-07-23 |
JPH09176039A (ja) | 1997-07-08 |
IL119412A0 (en) | 1997-01-10 |
AR004088A1 (es) | 1998-09-30 |
CN1161381C (zh) | 2004-08-11 |
TR199600852A2 (tr) | 1997-05-21 |
EP0785215B1 (en) | 2002-06-05 |
ATE218584T1 (de) | 2002-06-15 |
ES2177721T3 (es) | 2002-12-16 |
KR970021096A (ko) | 1997-05-28 |
RU2174407C2 (ru) | 2001-10-10 |
CN1154371A (zh) | 1997-07-16 |
IL119412A (en) | 2000-07-26 |
HU222043B1 (hu) | 2003-04-28 |
AU7037896A (en) | 1997-05-01 |
BR9605220B1 (pt) | 2010-10-19 |
DK0785215T3 (da) | 2002-09-16 |
TR199600852A3 (es) | 1997-05-21 |
CA2188508A1 (en) | 1997-04-25 |
HU9602923D0 (en) | 1996-12-30 |
DE69621577T2 (de) | 2003-01-16 |
AU711081B2 (en) | 1999-10-07 |
BR9605220A (pt) | 1998-07-21 |
DE69621577D1 (de) | 2002-07-11 |
US5691455A (en) | 1997-11-25 |
CA2188508C (en) | 2005-12-20 |
HUP9602923A1 (hu) | 1999-02-01 |
KR100498532B1 (ko) | 2005-10-06 |
JP4086922B2 (ja) | 2008-05-14 |
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