MX9300677A - IMPROVED PROCEDURE FOR THE PREPARATION OF SUBSTITUTED STEROID DIES. - Google Patents

IMPROVED PROCEDURE FOR THE PREPARATION OF SUBSTITUTED STEROID DIES.

Info

Publication number
MX9300677A
MX9300677A MX9300677A MX9300677A MX9300677A MX 9300677 A MX9300677 A MX 9300677A MX 9300677 A MX9300677 A MX 9300677A MX 9300677 A MX9300677 A MX 9300677A MX 9300677 A MX9300677 A MX 9300677A
Authority
MX
Mexico
Prior art keywords
preparation
dies
improved procedure
substituted steroid
substituted
Prior art date
Application number
MX9300677A
Other languages
Spanish (es)
Inventor
Neil Howard Baine
Michael Maguire
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MX9300677A publication Critical patent/MX9300677A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se ha inventado un procedimiento mejorado para la preparación de dienos esteroidales substituidos.An improved process for the preparation of substituted steroidal dienes has been invented.

MX9300677A 1992-02-07 1993-02-08 IMPROVED PROCEDURE FOR THE PREPARATION OF SUBSTITUTED STEROID DIES. MX9300677A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83227992A 1992-02-07 1992-02-07

Publications (1)

Publication Number Publication Date
MX9300677A true MX9300677A (en) 1994-07-29

Family

ID=25261205

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300677A MX9300677A (en) 1992-02-07 1993-02-08 IMPROVED PROCEDURE FOR THE PREPARATION OF SUBSTITUTED STEROID DIES.

Country Status (13)

Country Link
EP (1) EP0626972A4 (en)
JP (1) JPH07505618A (en)
KR (1) KR950700320A (en)
CN (1) CN1078474A (en)
AU (1) AU3612893A (en)
CA (1) CA2129347A1 (en)
IL (1) IL104601A0 (en)
MA (1) MA22787A1 (en)
MX (1) MX9300677A (en)
SI (1) SI9300067A (en)
TW (1) TW241266B (en)
WO (1) WO1993016098A1 (en)
ZA (1) ZA93802B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104602A (en) * 1992-02-07 1997-07-13 Smithkline Beecham Corp Process for the preparation of 3-carbonylandrostadiene- 17-carboxamides and intermediates for this process
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946834A (en) * 1988-12-23 1990-08-07 Smithkline Beecham Corporation Phosphonic acid substituted steroids as steroid 5α-reductase inhibitors
US5032586A (en) * 1989-08-24 1991-07-16 Smithkline Beecham Corporation 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase
US5091380A (en) * 1990-06-28 1992-02-25 Merck & Co., Inc. N-monosubstituted adamantyl/norbornanyl 17β-carbamides of 3-carboxy-androst-3,5-dienes as testosterone 5α-reductase inhibitors

Also Published As

Publication number Publication date
JPH07505618A (en) 1995-06-22
EP0626972A1 (en) 1994-12-07
IL104601A0 (en) 1993-07-08
TW241266B (en) 1995-02-21
KR950700320A (en) 1995-01-16
ZA93802B (en) 1993-11-05
CN1078474A (en) 1993-11-17
EP0626972A4 (en) 1995-01-04
MA22787A1 (en) 1993-10-01
WO1993016098A1 (en) 1993-08-19
AU3612893A (en) 1993-09-03
SI9300067A (en) 1993-09-30
CA2129347A1 (en) 1993-08-19

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