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Priority claimed from GB929202298Aexternal-prioritypatent/GB9202298D0/en
Application filed by Zeneca Limited Y Zeneca PharmafiledCriticalZeneca Limited Y Zeneca Pharma
Publication of MX9300553ApublicationCriticalpatent/MX9300553A/en
La presente invención se refiere a los carbapems y se proporciona un compuesto que contienen al grupo de fenilo substituído oncarboxi. La invención además se refiere a los procedimientos para su preparación, a los compuestos intermedios para su preparación, a su uso como agentes terapéuticos, y a las composiciones farmacéuticas que contienen a los mismos. Los compuestos de la invención son antibióticos, y se pueden usar para el tratamiento de cualquier enfermedad que está tratada convencionalmente con los antibióticos, por ejemplo, en el tratamiento de infecciones bacteriales, en mamíferos, incluyendo a los humanos.The present invention relates to carbapems and a compound containing the oncarboxy substituted phenyl group is provided. The invention further relates to processes for their preparation, to intermediates for their preparation, to their use as therapeutic agents, and to pharmaceutical compositions containing the same. The compounds of the invention are antibiotics, and can be used for the treatment of any disease that is conventionally treated with antibiotics, for example, in the treatment of bacterial infections, in mammals, including humans.
ANTIBIOTIC COMPOUNDS OF CEPHALOSPORIN, USE OF THE SAME TO PREPARE PHARMACEUTICAL COMPOSITIONS, SUCH PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM, INTERMEDIATE COMPOUNDS OF APPLICATION IN THE PREPARATION OF THE FIRST INTERESTS AND PREPARATION OF SUCH COMPOSITIONS
7-acylamino-3-iminomethyl (substituted) cephalosporin compound a process for its production intermediates in its production a pharmaceutical composition containing such compounds its use as pharmaceutical compounds and a method of treating microbial diseases by administration of such compounds
NEW 1,2,3,4-TETRAHIDRO-2-NAFTALENAMINAS FENILO-SUBSTITUTED IN THE AROMATIC RING, ITS PREPARATION, ITS THERAPEUTIC APPLICATIONS AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
COMPOUNDS WHICH ARE DERIVATIVE FROM THE ANTIBIOTICS MACROLIDES ROSARAMYCIN, REPROMYCIN, 5-MICAMINOSYLTILONOLIDE, DESMYCO-SINE, LACTENOCINE, O-DESMETIL-LACTENOCINE, CIRRAMYCIN A1, AND 23-DEOXYMICAMINOSYLTILONOLIDE