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Priority claimed from GB929201095Aexternal-prioritypatent/GB9201095D0/en
Priority claimed from GB929213572Aexternal-prioritypatent/GB9213572D0/en
Priority claimed from GB929223735Aexternal-prioritypatent/GB9223735D0/en
Priority claimed from GB939300059Aexternal-prioritypatent/GB9300059D0/en
Application filed by Zeneca LtdfiledCriticalZeneca Ltd
Publication of MX9300277ApublicationCriticalpatent/MX9300277A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
La invención se refiere a derivados de quinazolina de la fórmula (I), procedimiento para su preparación; composiciones farmacéuticas que contienen a los mismos y el uso de las propiedades inhibitorias de la quinasa de tirosina del receptor de los compuestos en el tratamiento del cáncer.The invention relates to quinazoline derivatives of formula (I), process for their preparation; pharmaceutical compositions containing the same and the use of the compounds receptor tyrosine kinase inhibitory properties in the treatment of cancer.
HETERO-CYCLIC COMPOUNDS FUSED AS PROTEIN INHIBITORS, THYROSINE KINASE, THEIR PREPARATION METHODS, INTERMEDIARY USE IN MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
IMIDAZOLE COMPOUNDS USEFUL FOR THE TREATMENT OF PATHOLOGIES MEDIATED BY CYTOKINES; PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM; PROCESS TO PREPARE SUCH COMPOUNDS; USE OF THE SAME TO PREPARE SUCH COMPOSITIONS; INTERMEDIATE COMPOUNDS AND PROCESSES FOR ITS PREPARATION.
Compound, pharmaceutical composition, methods of treating a disorder mediated by TNF and p38 kinase, inflammation and arthritis and the process of preparing pyrazoles
SMALL MOLECULES, THE INTERMEDIARIES FOR THEIR SYNTHESIS, THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE TO PREPARE A MEDICINAL PRODUCT INTENDED FOR TREATMENT OR PROPHYLAXIS OF INFLAMMATORY DISEASES OR MEDIATIONED BY IMMUNE CELLS
TRICYCLIC COMPOUNDS USEFUL TO INHIBIT THE FUNCTION OF PROTEIN G AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES, PHARMACEUTICAL COMPOSITION THAT INCLUDES THEM AND THE USE OF SUCH COMPOUNDS FOR THE MANUFACTURE OF MEDICINES
HETEROAROMATIC COMPOUNDS REPLACED AS INHIBIDORESS TIROSIN QUINASA, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF MEDICINES
Substituted pyrazole compound, pharmaceutical composition, processes for treating a tnf mediated disorder, a p38 kinase mediated disorder, inflammation and arthritis, and for preparing pyrazoles
2-AMINO-6-ANILINE-PURINE DERIVATIVES AND PROCEDURE AND NEW INTERMEDIARIES FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS THAT INCLUDE SUCH DERIVATIVES AND THE USE OF THESE DERIVATIVES AS MEDICINES.
INDOL-3-GLIOXILAMIDAS N-SUBSTITUTED WITH ANTI-ASMATIC, ANTI-ALLERGIC AND IMMUNOSUPPRESSOR / IMMUNOMODULATOR EFFECTS, PROCEDURES FOR THEIR PREPARATION, PHARMACEUTICAL STRUCTURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.