MX9204905A - Acidos aminometanodifosfonicos n-substituidos y procedimiento para su obtencion - Google Patents

Acidos aminometanodifosfonicos n-substituidos y procedimiento para su obtencion

Info

Publication number: MX9204905A
Authority: MX; Mexico
Prior art keywords: acids; substituted; aminomethaniphyphosphonic; procedure; obtaining
Prior art date: 1991-08-27

Application number

MX9204905A

Other languages

English (en)

Inventor

Knut Alfred Jaeggi

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-08-27

Filing date

1992-08-25

Publication date

1993-04-01

1992-08-25 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1993-04-01 Publication of MX9204905A publication Critical patent/MX9204905A/es

Links

239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
101100490437 Mus musculus Acvrl1 gene Proteins 0.000 abstract 1
-1 N-substituted aminomethanediphosphonic acids Chemical class 0.000 abstract 1
230000003913 calcium metabolism Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Dental Preparations (AREA)

MX9204905A 1991-08-27 1992-08-25 Acidos aminometanodifosfonicos n-substituidos y procedimiento para su obtencion MX9204905A (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP91810682		1991-08-27

Publications (1)

Publication Number	Publication Date
MX9204905A true MX9204905A (es)	1993-04-01

Family

ID=8208873

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX9204905A MX9204905A (es)	1991-08-27	1992-08-25	Acidos aminometanodifosfonicos n-substituidos y procedimiento para su obtencion

Country Status (19)

Country	Link
US (1)	US5281748A (es)
EP (1)	EP0531253B1 (es)
JP (1)	JPH05222074A (es)
KR (1)	KR930004317A (es)
AT (1)	ATE147396T1 (es)
AU (1)	AU657983B2 (es)
CA (1)	CA2076801A1 (es)
DE (1)	DE69216514T2 (es)
DK (1)	DK0531253T3 (es)
ES (1)	ES2096061T3 (es)
FI (1)	FI923797A (es)
GR (1)	GR3022243T3 (es)
HU (1)	HUT62303A (es)
IL (1)	IL102959A (es)
MX (1)	MX9204905A (es)
NO (1)	NO923331L (es)
NZ (1)	NZ244078A (es)
TW (1)	TW207543B (es)
ZA (1)	ZA926434B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0541037A3 (en) *	1991-11-06	1997-02-26	Takeda Chemical Industries Ltd	Squalene synthetase inhibitory composition and use thereof
TW258729B (es) *	1992-06-22	1995-10-01	Ciba Geigy
DE4223940A1 (de) *	1992-07-21	1994-01-27	Boehringer Mannheim Gmbh	Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
GB9300641D0 (en) *	1993-01-14	1993-03-03	Zeneca Ltd	Process
DE19719680A1 (de)	1997-05-09	1998-11-19	Boehringer Mannheim Gmbh	Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
IT1303672B1 (it)	1998-07-28	2001-02-23	Nicox Sa	Sali nitrati di farmaci attivi nei disordini ossei

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2316396C3 (de) *	1973-04-02	1975-09-18	Joh. A. Benckiser Gmbh, 6700 Ludwigshafen	N(1,1-Di-phosphono-äthyl)acetamidin, seine Herste lung und Verwendung zur Steinverhütung
DE3208600A1 (de) *	1982-03-10	1983-09-22	Henkel KGaA, 4000 Düsseldorf	Amidinodiphosphonsaeuren
US4761406A (en) *	1985-06-06	1988-08-02	The Procter & Gamble Company	Regimen for treating osteoporosis
DE3623397A1 (de) *	1986-07-11	1988-01-14	Boehringer Mannheim Gmbh	Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4963681A (en) *	1987-07-06	1990-10-16	Norwich Eaton Pharmaceuticals, Inc.	Process for synthesis of aminomethylene phosphonoalkylphosphinates
PH26923A (en) *	1989-03-08	1992-12-03	Ciba Geigy	N-substituted amino alkanediphosphonic acids
IE912115A1 (en) *	1990-06-25	1992-01-01	Takeda Chemical Industries Ltd	Bisphosphonic acid derivatives, their production and use
US5043099A (en) *	1990-07-13	1991-08-27	Kreh Robert P	Mono- and di-substituted (diphosphonoalkylamino methyl)-4-hydroxybenzenesulfonic acid
DE69116838T2 (de) *	1990-12-19	1996-06-13	Takeda Chemical Industries Ltd	Bisphosphonsäurederivate, ihre Produktion und ihre Verwendung

1992
- 1992-08-18 TW TW081106522A patent/TW207543B/zh active
- 1992-08-18 ES ES92810629T patent/ES2096061T3/es not_active Expired - Lifetime
- 1992-08-18 DK DK92810629.3T patent/DK0531253T3/da active
- 1992-08-18 AT AT92810629T patent/ATE147396T1/de active
- 1992-08-18 DE DE69216514T patent/DE69216514T2/de not_active Expired - Fee Related
- 1992-08-18 EP EP92810629A patent/EP0531253B1/en not_active Expired - Lifetime
- 1992-08-21 US US07/936,982 patent/US5281748A/en not_active Expired - Fee Related
- 1992-08-24 FI FI923797A patent/FI923797A/fi not_active Application Discontinuation
- 1992-08-25 CA CA002076801A patent/CA2076801A1/en not_active Abandoned
- 1992-08-25 MX MX9204905A patent/MX9204905A/es unknown
- 1992-08-25 JP JP4225966A patent/JPH05222074A/ja active Pending
- 1992-08-25 AU AU21288/92A patent/AU657983B2/en not_active Ceased
- 1992-08-25 NZ NZ244078A patent/NZ244078A/en unknown
- 1992-08-26 IL IL102959A patent/IL102959A/en not_active IP Right Cessation
- 1992-08-26 HU HU9202754A patent/HUT62303A/hu unknown
- 1992-08-26 NO NO92923331A patent/NO923331L/no unknown
- 1992-08-26 ZA ZA926434A patent/ZA926434B/xx unknown
- 1992-08-26 KR KR1019920015404A patent/KR930004317A/ko not_active Application Discontinuation
1997
- 1997-01-09 GR GR960403659T patent/GR3022243T3/el unknown

Also Published As

Publication number	Publication date
EP0531253B1 (en)	1997-01-08
FI923797A0 (fi)	1992-08-24
CA2076801A1 (en)	1993-02-28
EP0531253A1 (en)	1993-03-10
ZA926434B (en)	1993-04-28
FI923797A (fi)	1993-02-28
GR3022243T3 (en)	1997-04-30
NZ244078A (en)	1994-12-22
AU2128892A (en)	1993-03-04
DK0531253T3 (da)	1997-01-27
JPH05222074A (ja)	1993-08-31
HU9202754D0 (en)	1992-12-28
KR930004317A (ko)	1993-03-22
DE69216514T2 (de)	1997-07-31
AU657983B2 (en)	1995-03-30
NO923331D0 (no)	1992-08-26
ES2096061T3 (es)	1997-03-01
ATE147396T1 (de)	1997-01-15
DE69216514D1 (de)	1997-02-20
US5281748A (en)	1994-01-25
TW207543B (es)	1993-06-11
IL102959A0 (en)	1993-01-31
IL102959A (en)	1998-01-04
HUT62303A (en)	1993-04-28
NO923331L (no)	1993-03-01

Publication	Publication Date	Title
NO940038D0 (no)	1994-01-05	Arylsulfonamido-substituerte hydrokamsyrer
NO941052D0 (no)	1994-03-23	Benzimidazolforbindelser, deres anvendelse og fremstilling
MA22014A1 (fr)	1991-07-01	Derives d'acides amines .
CY1110745T1 (el)	2015-06-10	Παραγωγα πυρρολιδονης ως αναστολεις μαοβ
NO924915D0 (no)	1992-12-18	Sakkarinderivater med inhiberende virkning paa protolytiske enzymer
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
DE69716810D1 (de)	2002-12-12	2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
DE68923151D1 (de)	1995-07-27	Verwendung von Trifluormethylphenyl-Tetrahydropyridinen zur Herstellung von Arzneimitteln zur Behandlung anxio-depressiver Erkrankungen.
MX9204905A (es)	1993-04-01	Acidos aminometanodifosfonicos n-substituidos y procedimiento para su obtencion
ES2039267T3 (es)	1993-09-16	Dihidropiridinamidas, procedimiento para su preparacion y su empleo en medicamentos.
DK0610078T3 (da)	1997-10-20	Cytotoksisk og antiviral forbindelse.
NO170881C (no)	1992-12-23	Salicylsyreamider og deres anvendelse, i kosmetiske sammensetninger
ATE137759T1 (de)	1996-05-15	S'-adenosyl-methionin-decarboxylase-inhibitoren
DE3880304D1 (de)	1993-05-19	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
PT889044E (pt)	2005-01-31	Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central
DK730488A (da)	1989-07-01	Synergistisk kombination af decarboxylasehaemmere og l-dopa-pellets
FI812773L (fi)	1982-03-13	Foerfarande foer framstaellning av n-/4-/(2,4-diamino-6-pteridinyl)-metyl/metylamino/benzoyl/glutaminsyra
FR2583756B1 (fr)	1990-01-12	Procede de preparation des derives de la 2-halo-nicergoline et leurs sels d'addition avec des acides ainsi que des 2-halonicergolines nouvelles, compositions comportant des 2-halonicergolines et procede de preparation
SE8005309L (sv)	1981-02-18	Nya 5alfa-pregnan-20-ol-derivat och salter derav med syror, sett for framstellning samt anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar
ES2086395T3 (es)	1996-07-01	Fosfolipidos para el tratamiento de esclerosis multiple.