MX9204190A - Derivdos de 2-(4-hidroxipiperidino)-1-alcanol como agentes antiisquemicos. - Google Patents

Derivdos de 2-(4-hidroxipiperidino)-1-alcanol como agentes antiisquemicos.

Info

Publication number
MX9204190A
MX9204190A MX9204190A MX9204190A MX9204190A MX 9204190 A MX9204190 A MX 9204190A MX 9204190 A MX9204190 A MX 9204190A MX 9204190 A MX9204190 A MX 9204190A MX 9204190 A MX9204190 A MX 9204190A
Authority
MX
Mexico
Prior art keywords
hydroxipiperidine
alcanol
ischemical
derivatives
agents
Prior art date
Application number
MX9204190A
Other languages
English (en)
Inventor
Willard Mckowan Welch Jr
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9204190A publication Critical patent/MX9204190A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX9204190A 1991-07-17 1992-07-16 Derivdos de 2-(4-hidroxipiperidino)-1-alcanol como agentes antiisquemicos. MX9204190A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17

Publications (1)

Publication Number Publication Date
MX9204190A true MX9204190A (es) 1993-01-01

Family

ID=24940103

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204190A MX9204190A (es) 1991-07-17 1992-07-16 Derivdos de 2-(4-hidroxipiperidino)-1-alcanol como agentes antiisquemicos.

Country Status (22)

Country Link
EP (1) EP0594729A1 (es)
JP (1) JP2571904B2 (es)
KR (1) KR0165003B1 (es)
CN (1) CN1043759C (es)
AU (1) AU655840B2 (es)
BR (1) BR9206272A (es)
CA (1) CA2113568A1 (es)
CZ (1) CZ284133B6 (es)
EG (1) EG20048A (es)
FI (2) FI940192A0 (es)
HU (1) HUT70528A (es)
IE (1) IE922311A1 (es)
IL (1) IL102473A (es)
MX (1) MX9204190A (es)
NO (1) NO180445C (es)
NZ (1) NZ243580A (es)
PL (1) PL169884B1 (es)
PT (1) PT100689B (es)
RU (1) RU2065859C1 (es)
TW (1) TW201732B (es)
WO (1) WO1993002052A1 (es)
ZA (1) ZA925306B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
WO1994010166A1 (en) * 1992-10-30 1994-05-11 Pfizer Inc. Neuroprotective 3,4-dihydro-2(1h)-quinolone compounds
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
WO2000061558A1 (fr) * 1999-04-09 2000-10-19 Mochida Pharmaceutical Co., Ltd. Remedes pour douleurs neurogenes
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
AU1153601A (en) 1999-10-29 2001-05-08 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole NMDA NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
CZ20032258A3 (cs) 2001-02-23 2004-01-14 Merck & Co., Inc. N-substituované nearylové heterocyklické sloučeniny
WO2002080928A1 (en) 2001-04-03 2002-10-17 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists
US7494987B2 (en) 2002-11-25 2009-02-24 Mochida Pharmaceutical Co., Ltd. Agent for treating respiratory diseases containing 4-hydroxypiperidine derivative as active ingredient
EP1673367A1 (en) * 2003-10-08 2006-06-28 Pfizer, Inc. Fused lactam compounds
TWI409289B (zh) 2010-09-02 2013-09-21 Taiwan Union Technology Corp 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (fr) * 1983-05-19 1985-10-25 Synthelabo Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
EP0554247B1 (en) * 1990-05-10 2000-04-26 Pfizer Inc. Neuroprotective indolone and related derivatives

Also Published As

Publication number Publication date
CN1068566A (zh) 1993-02-03
CN1043759C (zh) 1999-06-23
NO180445C (no) 1997-04-23
EP0594729A1 (en) 1994-05-04
JPH06504293A (ja) 1994-05-19
TW201732B (es) 1993-03-11
IL102473A0 (en) 1993-01-14
FI981956A (fi) 1998-09-11
PL169884B1 (pl) 1996-09-30
NO940144D0 (no) 1994-01-14
JP2571904B2 (ja) 1997-01-16
IL102473A (en) 1997-07-13
CZ400892A3 (en) 1994-03-16
KR0165003B1 (en) 1999-01-15
NO940144L (no) 1994-01-14
PT100689B (pt) 1999-06-30
ZA925306B (en) 1994-01-17
NZ243580A (en) 1994-10-26
IE922311A1 (en) 1993-01-27
EG20048A (en) 1997-03-27
CZ284133B6 (cs) 1998-08-12
PT100689A (pt) 1993-10-29
FI940192A (fi) 1994-01-14
RU2065859C1 (ru) 1996-08-27
AU655840B2 (en) 1995-01-12
WO1993002052A1 (en) 1993-02-04
FI981956A0 (fi) 1998-09-11
HUT70528A (en) 1995-10-30
AU2322592A (en) 1993-02-23
BR9206272A (pt) 1995-04-11
HU9400136D0 (en) 1994-05-30
NO180445B (no) 1997-01-13
FI940192A0 (fi) 1994-01-14
CA2113568A1 (en) 1993-02-04

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