MX9203763A - THERAPEUTIC POLYPEPTIDES BASED ON THE VON WILLEBRAND FACTOR - Google Patents

THERAPEUTIC POLYPEPTIDES BASED ON THE VON WILLEBRAND FACTOR

Info

Publication number
MX9203763A
MX9203763A MX9203763A MX9203763A MX9203763A MX 9203763 A MX9203763 A MX 9203763A MX 9203763 A MX9203763 A MX 9203763A MX 9203763 A MX9203763 A MX 9203763A MX 9203763 A MX9203763 A MX 9203763A
Authority
MX
Mexico
Prior art keywords
von willebrand
willebrand factor
therapeutic polypeptides
polypeptides based
therapeutic
Prior art date
Application number
MX9203763A
Other languages
Spanish (es)
Inventor
Michael N Chang
Daniel G Mcgarry
John R Regan
Zaverio M Ruggeri
Jerry L Ware
Original Assignee
Rhone Poulenc Rorer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Int filed Critical Rhone Poulenc Rorer Int
Publication of MX9203763A publication Critical patent/MX9203763A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un polipéptido como patrón sobre un fragmento de subunidad de factor de von Willebrand (vWF) madura, de tipo salvaje, que tiene uno o más sitios de unión o afinidad predeterminada para uno o más de los ligandos del grupo que consiste de colágeno.A polypeptide as a template on a mature, wild-type, von Willebrand factor subunit (vWF) fragment having one or more binding or predetermined affinity sites for one or more of the ligands from the group consisting of collagen.

MX9203763A 1991-06-28 1992-06-29 THERAPEUTIC POLYPEPTIDES BASED ON THE VON WILLEBRAND FACTOR MX9203763A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72058891A 1991-06-28 1991-06-28

Publications (1)

Publication Number Publication Date
MX9203763A true MX9203763A (en) 1993-08-01

Family

ID=24894560

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203763A MX9203763A (en) 1991-06-28 1992-06-29 THERAPEUTIC POLYPEPTIDES BASED ON THE VON WILLEBRAND FACTOR

Country Status (3)

Country Link
AU (1) AU2297792A (en)
MX (1) MX9203763A (en)
WO (1) WO1993000357A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900476A (en) * 1986-05-30 1999-05-04 The Scripps Research Institute Therapeutic domains of van Willebrand factor
WO1992017192A1 (en) * 1991-03-27 1992-10-15 The Scripps Research Institute Therapeutic fragments of von willebrand factor
FR2686901A1 (en) * 1992-01-31 1993-08-06 Rhone Poulenc Rorer Sa NOVEL ANTITHROMBOTIC POLYPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
IL109383A0 (en) * 1993-04-23 1994-07-31 Bio Technology General Corp Method for enhancing thrombolysis
US5709180A (en) * 1997-02-06 1998-01-20 General Motors Corporation Narrow cam two-step lifter
US7349393B2 (en) * 1999-12-02 2008-03-25 Verizon Business Global Llc Method and system for implementing an improved universal packet switching capability in a data switch
ES2434035T3 (en) 2004-12-27 2013-12-13 Baxter International Inc. Polymer-von Willebrand factor conjugates
CA2647314A1 (en) 2006-03-31 2007-11-08 Baxter International Inc. Pegylated factor viii
US7645860B2 (en) 2006-03-31 2010-01-12 Baxter Healthcare S.A. Factor VIII polymer conjugates

Also Published As

Publication number Publication date
AU2297792A (en) 1993-01-25
WO1993000357A1 (en) 1993-01-07

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