MX366915B - Métodos para preparar rotavirus inactivado. - Google Patents
Métodos para preparar rotavirus inactivado.Info
- Publication number
- MX366915B MX366915B MX2016000783A MX2016000783A MX366915B MX 366915 B MX366915 B MX 366915B MX 2016000783 A MX2016000783 A MX 2016000783A MX 2016000783 A MX2016000783 A MX 2016000783A MX 366915 B MX366915 B MX 366915B
- Authority
- MX
- Mexico
- Prior art keywords
- rotavirus
- inactivated
- bovine
- methods
- temperature
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12361—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a métodos para producir rotavirus inactivado directamente a partir de sobrenadantes de cultivo celular que contienen rotavirus activos o infecciosos (por ejemplo, rotavirus de origen bovino), sin un aislamiento o purificación previos de dicho rotavirus a partir de los sobrenadantes de cultivo celular. En algunas modalidades, el rotavirus inactivado (por ejemplo, rotavirus de origen bovino) se produce al calentar un volumen de sobrenadante de cultivo a al menos una temperatura a la cual el rotavirus se inactiva. En algunas modalidades, el rotavirus (por ejemplo, rotavirus de origen bovino) se inactiva una vez que el volumen entero se calienta a al menos una temperatura a la cual el rotavirus se inactiva. En algunas modalidades, la temperatura del sobrenadante de cultivo celular se mantiene durante una cantidad de tiempo adecuada, la cual puede determinarse usando cualquiera de las pruebas descritas en la presente. El rotavirus inactivado (por ejemplo, rotavirus de origen bovino) puede posteriormente aislarse del sobrenadante de cultivo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361856294P | 2013-07-19 | 2013-07-19 | |
PCT/US2014/047164 WO2015010002A1 (en) | 2013-07-19 | 2014-07-18 | Methods for preparing inactivated rotavirus |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2016000783A MX2016000783A (es) | 2016-04-27 |
MX366915B true MX366915B (es) | 2019-07-30 |
Family
ID=51293170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016000783A MX366915B (es) | 2013-07-19 | 2014-07-18 | Métodos para preparar rotavirus inactivado. |
Country Status (16)
Country | Link |
---|---|
US (1) | US10030232B2 (es) |
EP (1) | EP3021867B1 (es) |
JP (1) | JP6089150B2 (es) |
CN (1) | CN105451764B (es) |
AU (1) | AU2014290523B2 (es) |
BR (1) | BR112015032773A8 (es) |
CA (1) | CA2913662C (es) |
EA (1) | EA038610B1 (es) |
ES (1) | ES2732301T3 (es) |
HK (1) | HK1217174A1 (es) |
MX (1) | MX366915B (es) |
NZ (1) | NZ714544A (es) |
PL (1) | PL3021867T3 (es) |
PT (1) | PT3021867T (es) |
WO (1) | WO2015010002A1 (es) |
ZA (1) | ZA201508666B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109355263A (zh) * | 2018-12-11 | 2019-02-19 | 中国医学科学院医学生物学研究所 | 利用生物反应器生产轮状病毒的方法 |
CN114410592B (zh) * | 2021-12-30 | 2024-05-24 | 苏州百源基因技术有限公司 | 一种轮状病毒培养基及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101051986B1 (ko) | 2006-09-28 | 2011-07-26 | 중앙대학교 산학협력단 | 인간로타바이러스 및 이를 이용한 백신 조성물 |
CN101835488B (zh) * | 2007-09-04 | 2018-10-26 | 美国政府(由卫生和人类服务部、疾病控制和预防中心的部长所代表) | 轮状病毒的热灭活 |
CN103442730B (zh) * | 2011-01-05 | 2016-08-17 | 巴拉特生物技术国际有限公司 | 组合七价疫苗 |
-
2014
- 2014-07-18 NZ NZ714544A patent/NZ714544A/en unknown
- 2014-07-18 JP JP2016527120A patent/JP6089150B2/ja active Active
- 2014-07-18 EA EA201592175A patent/EA038610B1/ru unknown
- 2014-07-18 CN CN201480039910.9A patent/CN105451764B/zh active Active
- 2014-07-18 PT PT14748051T patent/PT3021867T/pt unknown
- 2014-07-18 MX MX2016000783A patent/MX366915B/es active IP Right Grant
- 2014-07-18 US US14/898,506 patent/US10030232B2/en active Active
- 2014-07-18 CA CA2913662A patent/CA2913662C/en active Active
- 2014-07-18 AU AU2014290523A patent/AU2014290523B2/en active Active
- 2014-07-18 PL PL14748051T patent/PL3021867T3/pl unknown
- 2014-07-18 WO PCT/US2014/047164 patent/WO2015010002A1/en active Application Filing
- 2014-07-18 EP EP14748051.1A patent/EP3021867B1/en active Active
- 2014-07-18 BR BR112015032773A patent/BR112015032773A8/pt not_active Application Discontinuation
- 2014-07-18 ES ES14748051T patent/ES2732301T3/es active Active
-
2015
- 2015-11-25 ZA ZA2015/08666A patent/ZA201508666B/en unknown
-
2016
- 2016-05-06 HK HK16105185.6A patent/HK1217174A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
HK1217174A1 (zh) | 2016-12-30 |
BR112015032773A2 (pt) | 2017-07-25 |
ZA201508666B (en) | 2017-07-26 |
JP2016525120A (ja) | 2016-08-22 |
CA2913662C (en) | 2021-05-04 |
PT3021867T (pt) | 2019-06-24 |
CN105451764A (zh) | 2016-03-30 |
WO2015010002A1 (en) | 2015-01-22 |
EP3021867B1 (en) | 2019-04-17 |
EA201592175A1 (ru) | 2016-08-31 |
EA038610B1 (ru) | 2021-09-22 |
CA2913662A1 (en) | 2015-01-22 |
US20160145583A1 (en) | 2016-05-26 |
CN105451764B (zh) | 2021-04-02 |
BR112015032773A8 (pt) | 2018-01-23 |
AU2014290523B2 (en) | 2016-12-08 |
NZ714544A (en) | 2016-11-25 |
PL3021867T3 (pl) | 2019-09-30 |
JP6089150B2 (ja) | 2017-03-01 |
ES2732301T3 (es) | 2019-11-21 |
MX2016000783A (es) | 2016-04-27 |
AU2014290523A1 (en) | 2015-12-24 |
EP3021867A1 (en) | 2016-05-25 |
US10030232B2 (en) | 2018-07-24 |
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Legal Events
Date | Code | Title | Description |
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HC | Change of company name or juridical status |
Owner name: NOXELL CORPORATION |
|
FG | Grant or registration |