MX363201B - Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico. - Google Patents

Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico.

Info

Publication number
MX363201B
MX363201B MX2013010127A MX2013010127A MX363201B MX 363201 B MX363201 B MX 363201B MX 2013010127 A MX2013010127 A MX 2013010127A MX 2013010127 A MX2013010127 A MX 2013010127A MX 363201 B MX363201 B MX 363201B
Authority
MX
Mexico
Prior art keywords
determining
pancreatic cancer
array
individual
test sample
Prior art date
Application number
MX2013010127A
Other languages
English (en)
Other versions
MX2013010127A (es
Inventor
Carl Arne Krister Borrebaeck
Lars Bertil Christer Wingren
Original Assignee
Immunovia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunovia Ab filed Critical Immunovia Ab
Publication of MX2013010127A publication Critical patent/MX2013010127A/es
Publication of MX363201B publication Critical patent/MX363201B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5406—IL-4
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5412—IL-6
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5437—IL-13

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a un procedimiento para determinar la presencia de cáncer pancreático en un individuo, que comprende o consiste en las etapas de: (a) proporcionar una muestra a ensayar del individuo y (b) determinar una firma biomarcadora de la muestra de ensayo midiendo la expresión en la muestra de ensayo de uno o más biomarcadores seleccionados del grupo definido en la Tabla III, en el que la expresión en la muestra de ensayo de uno o más biomarcadores seleccionados del grupo definido en la Tabla III es indicativa del cáncer pancreático que padece el individuo. La invención también comprende matrices y kits de partes para su uso en el procedimiento de la invención.
MX2013010127A 2011-03-04 2012-03-05 Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico. MX363201B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1103726.4A GB201103726D0 (en) 2011-03-04 2011-03-04 Method, array and use thereof
PCT/GB2012/050483 WO2012120288A2 (en) 2011-03-04 2012-03-05 Method, array and use thereof

Publications (2)

Publication Number Publication Date
MX2013010127A MX2013010127A (es) 2014-10-15
MX363201B true MX363201B (es) 2019-03-14

Family

ID=43923218

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010127A MX363201B (es) 2011-03-04 2012-03-05 Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico.

Country Status (9)

Country Link
US (4) US9863960B2 (es)
EP (1) EP2681563A2 (es)
JP (1) JP6161542B2 (es)
KR (2) KR20190101489A (es)
CN (2) CN107064518A (es)
CA (1) CA2828338A1 (es)
GB (1) GB201103726D0 (es)
MX (1) MX363201B (es)
WO (1) WO2012120288A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6115801B2 (ja) 2007-03-27 2017-04-19 イミュノヴィア・アーベー 腺癌の検出のための蛋白質シグネチャー／マーカー
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
GB201319878D0 (en) * 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof
KR101658164B1 (ko) * 2014-04-28 2016-09-21 서강대학교산학협력단 브롬 동위원소 신호를 이용한 자유 라디칼-개시 펩타이드 시퀀싱 질량분석
KR20150129932A (ko) * 2014-05-12 2015-11-23 연세대학교 산학협력단 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트
CN105572276B (zh) * 2014-11-07 2018-12-18 上海市第六人民医院 胰腺癌诊断标记物组合、应用及其测定方法
CN104698170A (zh) * 2015-03-17 2015-06-10 任传利 Il-11作为生物标记物在胰腺癌诊断和预后评价的方法
EP3073268A1 (en) 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
JP5852759B1 (ja) * 2015-04-01 2016-02-03 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
GB201516801D0 (en) 2015-09-22 2015-11-04 Immunovia Ab Method, array and use thereof
JP5970123B1 (ja) * 2015-12-04 2016-08-17 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
JP6392201B2 (ja) * 2015-12-04 2018-09-19 株式会社キュービクス 遺伝子発現解析による膵臓癌の検出
KR101594287B1 (ko) 2016-01-13 2016-02-15 연세대학교 산학협력단 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트
RU2018131560A (ru) * 2016-02-05 2020-03-04 Дана Дженетик А/С Способы диагностики и лечения злокачественной опухоли с использованием антител, которые связываются с с1-инактиватором, с-реактивным белком и/или компонентом комплемента с4
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
DE202017007366U1 (de) 2016-12-16 2021-02-17 The Brigham And Women's Hospital, Inc. Sensor-Array zum Erfassen einer relativen Proteinkonzentration
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
GB201701572D0 (en) 2017-01-31 2017-03-15 Immunovia Ab Methods, arrays and uses thereof
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
BR112021008999A2 (pt) 2018-11-07 2021-08-10 Seer, Inc. composições, métodos e sistemas para a análise de proteína corona e seus usos.
EP3903105A1 (en) 2019-02-18 2021-11-03 The University Of Liverpool Method of diagnosis
CN117233413A (zh) 2019-08-05 2023-12-15 禧尔公司 用于样品制备、数据生成和蛋白质冠分析的***和方法
GB202010970D0 (en) * 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
CN113655144A (zh) * 2021-08-09 2021-11-16 大连医科大学附属第一医院 一种基于丙酮酸激酶和α-2-HS-糖蛋白的早期预警重症急性胰腺炎的预测模型

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3169789D1 (en) 1980-05-02 1985-05-15 Edward P Davis Leg aid device
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US5856090A (en) 1994-09-09 1999-01-05 The Scripps Research Institute DNA-methylase linking reaction
GB9703369D0 (en) 1997-02-18 1997-04-09 Lindqvist Bjorn H Process
JP4194080B2 (ja) 2003-02-19 2008-12-10 茂 森村 膵癌検出用マーカー
US20050277137A1 (en) 2003-08-15 2005-12-15 University Of Pittsburgh Diagnostic multimarker serological profiling
US20060106119A1 (en) 2004-01-12 2006-05-18 Chang-Jie Guo Novel integration for CO and H2 recovery in gas to liquid processes
JP2008514205A (ja) * 2004-09-29 2008-05-08 財団法人実験動物中央研究所 Ｎｏｇマウスを用いた高転移性細胞株の樹立
US8383357B2 (en) 2005-03-16 2013-02-26 OSI Pharmaceuticals, LLC Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors
WO2006110599A2 (en) 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Cacna1e in cancer diagnosis, detection and treatment
JP2008535494A (ja) 2005-04-07 2008-09-04 サグレシュ ディスカバリー， インコーポレイテッド 癌関連遺伝子（ｐｒｌｒ）
JP2007051880A (ja) 2005-08-15 2007-03-01 Tokyo Univ Of Science 膵臓癌の検出方法、膵臓癌の診断キット
WO2007107774A2 (en) * 2006-03-22 2007-09-27 Cartela R & D Ab Integrin alpha-10 subunit as therapeutic target and diagnostic/prognostic marker for cancer
KR100819122B1 (ko) * 2006-09-30 2008-04-04 남명진 췌장암 진단용 키트
US9353415B2 (en) 2006-12-19 2016-05-31 Thomson Reuters (Scientific) Llc Methods for functional analysis of high-throughput experimental data and gene groups identified therefrom
JP6115801B2 (ja) * 2007-03-27 2017-04-19 イミュノヴィア・アーベー 腺癌の検出のための蛋白質シグネチャー／マーカー
GB0723179D0 (en) * 2007-11-27 2008-01-02 Immunovia Ab Diagnostic methods and arrays for use in the same
US20120004289A1 (en) * 2009-03-06 2012-01-05 The Johns Hopkins University Annexin a11 and associated genes as biomarkers for cancer
CN101880707A (zh) * 2009-05-05 2010-11-10 中国人民解放军第二军医大学 microRNA-21在鉴别胰腺癌中的应用
CN101613748A (zh) * 2009-06-09 2009-12-30 中国人民解放军第二军医大学 一种检测胰腺癌血清标志物的方法
SG168431A1 (en) * 2009-07-23 2011-02-28 Univ Singapore Cancer biomarker and the use thereof
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
GB201319878D0 (en) 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof

Also Published As

Publication number Publication date
KR20140040118A (ko) 2014-04-02
US20200088742A1 (en) 2020-03-19
GB201103726D0 (en) 2011-04-20
CN103534594A (zh) 2014-01-22
CA2828338A1 (en) 2012-09-13
US20210356478A1 (en) 2021-11-18
WO2012120288A2 (en) 2012-09-13
CN107064518A (zh) 2017-08-18
US20180136231A1 (en) 2018-05-17
US20140038844A1 (en) 2014-02-06
KR102014890B1 (ko) 2019-08-27
MX2013010127A (es) 2014-10-15
KR20190101489A (ko) 2019-08-30
JP2014508298A (ja) 2014-04-03
WO2012120288A3 (en) 2013-01-10
US9863960B2 (en) 2018-01-09
EP2681563A2 (en) 2014-01-08
JP6161542B2 (ja) 2017-07-12

Similar Documents

Publication Publication Date Title
MX363201B (es) Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico.
MX2016006125A (es) Procedimiento, matriz y uso de los mismos.
WO2017050939A3 (en) Method and array for diagnosing pancreatic cancer in an individual
MX2018013621A (es) Metodo, matriz y uso de estos.
WO2012096545A3 (ko) 췌장암 암줄기세포 특성을 이용한 췌장암 신규 바이오마커 및 그의 용도
MX2019008911A (es) Metodos, matrices y usos de estos.
MX357550B (es) Microarn plasmaticos para la deteccion de cancer colorrectal temprano.
IN2014CN01970A (es)
EA030186B9 (ru) Способ проведения количественных анализов
EP4249605A3 (en) Methods for analyte detection
BR112012011230A2 (pt) fatores de risco e previsão de infarto do miocárdio
GB201207297D0 (en) Analytical methods and arrays for use in the same
AR089825A1 (es) Metodo para determinar la ubicacion, tamaño y condiciones in situ en un yacimiento de hidrocarburos con ecologia, geoquimica y grupos de biomarcadores
WO2013188686A3 (en) Biomarker test for prediction or early detection of preeclampsia and/or hellp syndrome
WO2013075055A3 (en) Kits and methods for assessing appendicitis
GB201014837D0 (en) Biomarker signatures and uses thereof
WO2014186761A3 (en) Methods for determining responsiveness to an anti-cd47 agent
EP3851856A3 (en) Method, array and use thereof
WO2015189591A3 (en) Method and arrays for use in diagnosing early breast cancer
EP2558597A4 (en) EARLY DETECTION AND STADIFICATION OF COLORECTAL CANCER USING A MICRO-RNA PANEL
GB201206323D0 (en) Methods and arrays for use in the same
MX336940B (es) Uso de compuestos mejoradores de señal en deteccion de electroquimioluminiscencia.
MX2015013993A (es) Procedimientos y series para su uso en los mismos.
MX2016005313A (es) Deteccion de la actividad de corte de una enzima.
AU2011263533A8 (en) Method,array and use thereof