MX361192B - Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease. - Google Patents

Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease.

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Publication number
MX361192B
MX361192B MX2011008969A MX2011008969A MX361192B MX 361192 B MX361192 B MX 361192B MX 2011008969 A MX2011008969 A MX 2011008969A MX 2011008969 A MX2011008969 A MX 2011008969A MX 361192 B MX361192 B MX 361192B
Authority
MX
Mexico
Prior art keywords
early
treatment
methods
osteoarthritis
disease
Prior art date
Application number
MX2011008969A
Other languages
Spanish (es)
Other versions
MX2011008969A (en
Inventor
Bautista Kouri Flores Juan
Raymundo Cruz Pérez José
Original Assignee
Centro De Investig Y De Estudios Avanzados Del I P N
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro De Investig Y De Estudios Avanzados Del I P N filed Critical Centro De Investig Y De Estudios Avanzados Del I P N
Priority to MX2011008969A priority Critical patent/MX361192B/en
Priority to PCT/IB2011/053758 priority patent/WO2012025910A1/en
Publication of MX2011008969A publication Critical patent/MX2011008969A/en
Publication of MX361192B publication Critical patent/MX361192B/en

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  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to methods of detection and treatment of osteoarthritis (OA) at early stages of development of the disease through the detection and neutralization of IL1 ß as an early biomarker of OA. The method of the invention also refers to the relationship of the expression of pro-inflammatory and anti-inflammatory cytokines in healthy cartilage and osteoarthritic cartilage as a mean to assess the role IL-1ß as a potential biomarker of early OA. The present invention also provides efficient methods for treating OA at early stages by using inhibitors of IL-1ß activity in the cartilage, thereby preventing the progression of OA to stages of difficult treatment or to reverse the damage on the cartilage by the presence of IL-1ß.
MX2011008969A 2010-08-26 2011-08-24 Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease. MX361192B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MX2011008969A MX361192B (en) 2011-08-24 2011-08-24 Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease.
PCT/IB2011/053758 WO2012025910A1 (en) 2010-08-26 2011-08-26 METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2011008969A MX361192B (en) 2011-08-24 2011-08-24 Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease.

Publications (2)

Publication Number Publication Date
MX2011008969A MX2011008969A (en) 2013-02-25
MX361192B true MX361192B (en) 2018-11-13

Family

ID=48740737

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011008969A MX361192B (en) 2010-08-26 2011-08-24 Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease.

Country Status (1)

Country Link
MX (1) MX361192B (en)

Also Published As

Publication number Publication date
MX2011008969A (en) 2013-02-25

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