MX361192B - Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease. - Google Patents
Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease.Info
- Publication number
- MX361192B MX361192B MX2011008969A MX2011008969A MX361192B MX 361192 B MX361192 B MX 361192B MX 2011008969 A MX2011008969 A MX 2011008969A MX 2011008969 A MX2011008969 A MX 2011008969A MX 361192 B MX361192 B MX 361192B
- Authority
- MX
- Mexico
- Prior art keywords
- early
- treatment
- methods
- osteoarthritis
- disease
- Prior art date
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- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The present invention relates to methods of detection and treatment of osteoarthritis (OA) at early stages of development of the disease through the detection and neutralization of IL1 ß as an early biomarker of OA. The method of the invention also refers to the relationship of the expression of pro-inflammatory and anti-inflammatory cytokines in healthy cartilage and osteoarthritic cartilage as a mean to assess the role IL-1ß as a potential biomarker of early OA. The present invention also provides efficient methods for treating OA at early stages by using inhibitors of IL-1ß activity in the cartilage, thereby preventing the progression of OA to stages of difficult treatment or to reverse the damage on the cartilage by the presence of IL-1ß.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2011008969A MX361192B (en) | 2011-08-24 | 2011-08-24 | Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease. |
PCT/IB2011/053758 WO2012025910A1 (en) | 2010-08-26 | 2011-08-26 | METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2011008969A MX361192B (en) | 2011-08-24 | 2011-08-24 | Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease. |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2011008969A MX2011008969A (en) | 2013-02-25 |
MX361192B true MX361192B (en) | 2018-11-13 |
Family
ID=48740737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011008969A MX361192B (en) | 2010-08-26 | 2011-08-24 | Methods of diagnosis and treatment of osteoarthritis at early stages using interleukin il-1ss as early biomarker of the disease. |
Country Status (1)
Country | Link |
---|---|
MX (1) | MX361192B (en) |
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2011
- 2011-08-24 MX MX2011008969A patent/MX361192B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
MX2011008969A (en) | 2013-02-25 |
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