MX359669B - Microorganismos modificados genéticamente capaces de producir beta-glucanos, y métodos para la producción de beta-glucanos. - Google Patents
Microorganismos modificados genéticamente capaces de producir beta-glucanos, y métodos para la producción de beta-glucanos.Info
- Publication number
- MX359669B MX359669B MX2014015733A MX2014015733A MX359669B MX 359669 B MX359669 B MX 359669B MX 2014015733 A MX2014015733 A MX 2014015733A MX 2014015733 A MX2014015733 A MX 2014015733A MX 359669 B MX359669 B MX 359669B
- Authority
- MX
- Mexico
- Prior art keywords
- glucans
- polypeptide
- producing beta
- activity
- genetically modified
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01034—1,3-Beta-glucan synthase (2.4.1.34)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a microorganismos modificados genéticamente capaces de producir beta-glucanos, caracterizados porque dicho microorganismo modificado genéticamente sobreexpresa: (i) un polinucleótido que codifica un polipéptido que tiene actividad de 1 ,3-ß-D-glucano sintasa, y/o (ii) un polipéptido que tiene actividad de 1 ,3-ß-D-glucano sintasa, en comparación con un microorganismo de control no modificado correspondiente de la misma cepa. La presente invención también se refiere al uso de un polinucleótido que codifica un polipéptido que tiene actividad de 1 ,3- ß -D-glucano sintasa o el uso de un polipéptido tal para producir ß-glucanos. Además, la presente invención se refiere a métodos para producir ß -glucanos que comprende introducir un promotor corriente arriba de un polinucleótido que codifica un polipéptido que tiene actividad de 1 ,3-ß-D-glucano sintasa que aumenta la expresión de dicho polinucleótido, o un polinucleótido que codifica un polipéptido que tiene actividad de 1 ,3-ß-D-glucano sintasa en un microorganismo capaz de sintetizar ß-glucanos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12174882 | 2012-07-04 | ||
| PCT/EP2013/064024 WO2014006088A1 (en) | 2012-07-04 | 2013-07-03 | Genetically modified microorganisms capable of producing beta-glucans and methods for producing beta-glucans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014015733A MX2014015733A (es) | 2015-11-16 |
| MX359669B true MX359669B (es) | 2018-10-05 |
Family
ID=48746510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014015733A MX359669B (es) | 2012-07-04 | 2013-07-03 | Microorganismos modificados genéticamente capaces de producir beta-glucanos, y métodos para la producción de beta-glucanos. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20150152453A1 (es) |
| EP (1) | EP2870239B1 (es) |
| CN (1) | CN104781397A (es) |
| AU (1) | AU2013285476A1 (es) |
| BR (1) | BR112015000032A2 (es) |
| CA (1) | CA2875603A1 (es) |
| CL (1) | CL2015000015A1 (es) |
| DK (1) | DK2870239T3 (es) |
| EA (1) | EA032367B1 (es) |
| ES (1) | ES2708199T3 (es) |
| MX (1) | MX359669B (es) |
| WO (1) | WO2014006088A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10208324B2 (en) | 2013-12-13 | 2019-02-19 | Basf Se | Recombinant microorganism for improved production of fine chemicals |
| CA2937359A1 (en) * | 2014-01-23 | 2015-07-30 | Wintershall Holding GmbH | Process for producing a beta-glucan polymer and genetically modified microorganisms useful in this process |
| CN109609525A (zh) * | 2019-01-10 | 2019-04-12 | 江苏大学 | 灰树花葡聚糖合成酶、其编码基因及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| CA1223831A (en) | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| JP2911554B2 (ja) | 1990-06-25 | 1999-06-23 | 台糖株式会社 | 抗ウィルス剤 |
| US5792608A (en) | 1991-12-12 | 1998-08-11 | Gilead Sciences, Inc. | Nuclease stable and binding competent oligomers and methods for their use |
| US5525711A (en) | 1994-05-18 | 1996-06-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Pteridine nucleotide analogs as fluorescent DNA probes |
-
2013
- 2013-07-03 US US14/412,212 patent/US20150152453A1/en not_active Abandoned
- 2013-07-03 CA CA2875603A patent/CA2875603A1/en not_active Abandoned
- 2013-07-03 EP EP13734062.6A patent/EP2870239B1/en active Active
- 2013-07-03 AU AU2013285476A patent/AU2013285476A1/en not_active Abandoned
- 2013-07-03 DK DK13734062.6T patent/DK2870239T3/en active
- 2013-07-03 WO PCT/EP2013/064024 patent/WO2014006088A1/en active Application Filing
- 2013-07-03 ES ES13734062T patent/ES2708199T3/es active Active
- 2013-07-03 EA EA201590148A patent/EA032367B1/ru not_active IP Right Cessation
- 2013-07-03 MX MX2014015733A patent/MX359669B/es active IP Right Grant
- 2013-07-03 BR BR112015000032A patent/BR112015000032A2/pt not_active Application Discontinuation
- 2013-07-03 CN CN201380035334.6A patent/CN104781397A/zh active Pending
-
2015
- 2015-01-05 CL CL2015000015A patent/CL2015000015A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2870239A1 (en) | 2015-05-13 |
| CL2015000015A1 (es) | 2015-03-06 |
| EA032367B1 (ru) | 2019-05-31 |
| EA201590148A1 (ru) | 2015-06-30 |
| WO2014006088A1 (en) | 2014-01-09 |
| MX2014015733A (es) | 2015-11-16 |
| DK2870239T3 (en) | 2019-02-25 |
| CN104781397A (zh) | 2015-07-15 |
| US20150152453A1 (en) | 2015-06-04 |
| EP2870239B1 (en) | 2018-10-31 |
| AU2013285476A1 (en) | 2015-01-22 |
| BR112015000032A2 (pt) | 2017-08-08 |
| ES2708199T3 (es) | 2019-04-09 |
| CA2875603A1 (en) | 2014-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |