MX357018B - Method for the early diagnosis of hepatocellular carcinoma. - Google Patents

Method for the early diagnosis of hepatocellular carcinoma.

Info

Publication number
MX357018B
MX357018B MX2013015064A MX2013015064A MX357018B MX 357018 B MX357018 B MX 357018B MX 2013015064 A MX2013015064 A MX 2013015064A MX 2013015064 A MX2013015064 A MX 2013015064A MX 357018 B MX357018 B MX 357018B
Authority
MX
Mexico
Prior art keywords
hepatocellular carcinoma
early diagnosis
ptgr1
chc
novel methods
Prior art date
Application number
MX2013015064A
Other languages
Spanish (es)
Other versions
MX2013015064A (en
Inventor
Isael Pérez Carreón Julio
Sánchez Rodríguez Ricardo
Original Assignee
Instituto Nac De Medicina Genomica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto Nac De Medicina Genomica filed Critical Instituto Nac De Medicina Genomica
Priority to MX2013015064A priority Critical patent/MX357018B/en
Priority to PCT/MX2014/000207 priority patent/WO2015093932A1/en
Publication of MX2013015064A publication Critical patent/MX2013015064A/en
Publication of MX357018B publication Critical patent/MX357018B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90206—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention relates to novel methods for the early diagnosis of hepatocellular carcinoma (CHC) by means of the detection of the genic products (mRNA or protein) of prostaglandin reductase 1 (Ptgr1) in biological samples, and to novel methods for determining whether a patient with CHC is a candidate for treatment with antitumoral compounds bioactivated by the Ptgr1.
MX2013015064A 2013-12-18 2013-12-18 Method for the early diagnosis of hepatocellular carcinoma. MX357018B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MX2013015064A MX357018B (en) 2013-12-18 2013-12-18 Method for the early diagnosis of hepatocellular carcinoma.
PCT/MX2014/000207 WO2015093932A1 (en) 2013-12-18 2014-12-16 Method for the early diagnosis of hepatocellular carcinoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2013015064A MX357018B (en) 2013-12-18 2013-12-18 Method for the early diagnosis of hepatocellular carcinoma.

Publications (2)

Publication Number Publication Date
MX2013015064A MX2013015064A (en) 2015-06-18
MX357018B true MX357018B (en) 2018-06-05

Family

ID=53403172

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013015064A MX357018B (en) 2013-12-18 2013-12-18 Method for the early diagnosis of hepatocellular carcinoma.

Country Status (2)

Country Link
MX (1) MX357018B (en)
WO (1) WO2015093932A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107663539B (en) * 2017-09-29 2020-12-01 中山大学附属第三医院 Use of circular RNA circ-PTGR1

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974667B2 (en) * 2000-06-14 2005-12-13 Gene Logic, Inc. Gene expression profiles in liver cancer
DE10136273A1 (en) * 2001-07-25 2003-02-13 Sabine Debuschewitz Molecular markers in hepatocellular carcinoma
EP1540342B1 (en) * 2002-07-03 2010-12-29 Illumigen Biosciences, Inc. Methods and compositions for diagnosing hepatocellular carcinoma
WO2004108964A1 (en) * 2003-06-04 2004-12-16 Agency For Science, Technology And Research Differentially regulated hepatocellular carcinoma genes and uses thereof
ES2324128A1 (en) * 2005-09-29 2009-07-30 Proyecto De Biomedicina Cima, S.L. Molecular markers of hepatocellular carcinoma and their applications
CN102618545B (en) * 2006-06-09 2014-12-10 株式会社益力多本社 Gene involved in immortalization of human cancer cell and use thereof
EP2864791A2 (en) * 2012-06-20 2015-04-29 Leibniz - Institut für Analytische Wissenschaften - ISAS - E.V. Specific biomarkers for hepatocellular carcinoma (hcc)

Also Published As

Publication number Publication date
MX2013015064A (en) 2015-06-18
WO2015093932A1 (en) 2015-06-25

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