MX356846B - Compuestos de metanotiona que tienen actividad antiviral. - Google Patents

Compuestos de metanotiona que tienen actividad antiviral.

Info

Publication number
MX356846B
MX356846B MX2014014007A MX2014014007A MX356846B MX 356846 B MX356846 B MX 356846B MX 2014014007 A MX2014014007 A MX 2014014007A MX 2014014007 A MX2014014007 A MX 2014014007A MX 356846 B MX356846 B MX 356846B
Authority
MX
Mexico
Prior art keywords
methanethione
compounds
antiviral activity
compound
formula
Prior art date
Application number
MX2014014007A
Other languages
English (en)
Other versions
MX2014014007A (es
Inventor
Homman Mohammed
Kingi Ngarita
Bergman Jan
Berg Robert
Original Assignee
Vironova Influenza Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48444409&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX356846(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vironova Influenza Ab filed Critical Vironova Influenza Ab
Publication of MX2014014007A publication Critical patent/MX2014014007A/es
Publication of MX356846B publication Critical patent/MX356846B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente invención se refiere a un compuesto de la fórmula (I). El compuesto es útil como un agente antiviral, en particular para el tratamiento de la influeza. Un método de preparación del compuesto de la fórmula (I) y una composición que comprende el compuesto de la fórmula (I). (ver Fórmula).
MX2014014007A 2012-05-18 2013-05-17 Compuestos de metanotiona que tienen actividad antiviral. MX356846B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261648700P 2012-05-18 2012-05-18
US201261659516P 2012-06-14 2012-06-14
US201261666286P 2012-06-29 2012-06-29
US201361774991P 2013-03-08 2013-03-08
PCT/EP2013/060266 WO2013171334A1 (en) 2012-05-18 2013-05-17 Methanethione compounds having antiviral activity

Publications (2)

Publication Number Publication Date
MX2014014007A MX2014014007A (es) 2015-05-11
MX356846B true MX356846B (es) 2018-06-18

Family

ID=48444409

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014007A MX356846B (es) 2012-05-18 2013-05-17 Compuestos de metanotiona que tienen actividad antiviral.

Country Status (21)

Country Link
US (1) US9359310B2 (es)
EP (1) EP2870141B1 (es)
JP (2) JP6484168B2 (es)
KR (1) KR102092207B1 (es)
CN (1) CN104540810B (es)
AU (1) AU2013261735B2 (es)
BR (1) BR112014028632B1 (es)
CA (1) CA2879816C (es)
CL (1) CL2014003116A1 (es)
DK (1) DK2870141T3 (es)
EA (1) EA029044B1 (es)
ES (1) ES2657942T3 (es)
HK (1) HK1210165A1 (es)
IL (1) IL235742A0 (es)
IN (1) IN2014DN10658A (es)
MX (1) MX356846B (es)
MY (1) MY169094A (es)
NZ (1) NZ702073A (es)
SG (1) SG11201407703QA (es)
WO (1) WO2013171334A1 (es)
ZA (1) ZA201409220B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013171334A1 (en) * 2012-05-18 2013-11-21 Vironova Ab Methanethione compounds having antiviral activity
CN107056762B (zh) * 2016-12-22 2020-08-28 四川百利药业有限责任公司 一种用作抗流感病毒的双羰基类似物
WO2021204923A1 (en) 2020-04-09 2021-10-14 Vironova Medical Ab Antiviral agents
WO2021204924A1 (en) 2020-04-09 2021-10-14 Vironova Medical Ab Compounds for use in the treatment of hypercytokinemia

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642390B2 (en) 2001-07-11 2003-11-04 Lexicon Pharmaceuticals, Inc. One step synthesis of 1,2,3-triazole carboxylic acids
EP1590329A1 (fr) * 2003-01-28 2005-11-02 Aventis Pharma S.A. Produits n-aryl-heteroaromatiques, compositions les contenant et utilisation
WO2009131957A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
MX2012001504A (es) * 2009-08-05 2012-06-01 Versitech Ltd Compuestos antivirales y metodos para elaborarlos y usarlos.
CN103209977A (zh) * 2010-09-28 2013-07-17 百时美施贵宝公司 作为广谱抗流感病毒剂的带有取代的杂芳基的新的哌嗪类似物
EP2484655A1 (en) 2011-02-04 2012-08-08 Vironova AB A thionation process and a thionating agent
WO2013171334A1 (en) * 2012-05-18 2013-11-21 Vironova Ab Methanethione compounds having antiviral activity
JP6762767B2 (ja) * 2016-06-01 2020-09-30 キヤノン株式会社 撮像素子、撮像装置、および撮像信号処理方法

Also Published As

Publication number Publication date
KR20150012289A (ko) 2015-02-03
EP2870141B1 (en) 2017-11-22
NZ702073A (en) 2017-07-28
EA201401277A1 (ru) 2015-04-30
CA2879816A1 (en) 2013-11-21
MX2014014007A (es) 2015-05-11
ZA201409220B (en) 2016-08-31
US9359310B2 (en) 2016-06-07
AU2013261735A1 (en) 2015-01-22
EA029044B1 (ru) 2018-02-28
US20150133468A1 (en) 2015-05-14
EP2870141A1 (en) 2015-05-13
SG11201407703QA (en) 2015-01-29
JP2015517516A (ja) 2015-06-22
IL235742A0 (en) 2015-02-01
DK2870141T3 (da) 2018-01-29
JP2018065817A (ja) 2018-04-26
CL2014003116A1 (es) 2015-08-07
CN104540810B (zh) 2017-01-18
BR112014028632B1 (pt) 2020-01-28
CA2879816C (en) 2020-07-07
WO2013171334A1 (en) 2013-11-21
KR102092207B1 (ko) 2020-03-23
JP6484168B2 (ja) 2019-03-13
ES2657942T3 (es) 2018-03-07
BR112014028632A2 (pt) 2017-06-27
IN2014DN10658A (es) 2015-08-28
AU2013261735B2 (en) 2017-07-20
HK1210165A1 (en) 2016-04-15
BR112014028632A8 (pt) 2018-04-03
MY169094A (en) 2019-02-18
CN104540810A (zh) 2015-04-22

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Legal Events

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Owner name: VIRONOVA INFLUENZA AB

FG Grant or registration