MX351818B - Compuestos antivirales. - Google Patents

Compuestos antivirales.

Info

Publication number
MX351818B
MX351818B MX2014003887A MX2014003887A MX351818B MX 351818 B MX351818 B MX 351818B MX 2014003887 A MX2014003887 A MX 2014003887A MX 2014003887 A MX2014003887 A MX 2014003887A MX 351818 B MX351818 B MX 351818B
Authority
MX
Mexico
Prior art keywords
compounds
viral compounds
rig
pathway
viral infection
Prior art date
Application number
MX2014003887A
Other languages
English (en)
Other versions
MX2014003887A (es
Inventor
P Iadonato Shawn
Bedard Kristin
Wang Imanaka Myra
W Fowler Kerry
Original Assignee
Kineta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kineta Inc filed Critical Kineta Inc
Publication of MX2014003887A publication Critical patent/MX2014003887A/es
Publication of MX351818B publication Critical patent/MX351818B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

En la presente se describen los compuestos y las composiciones relacionadas para el tratamiento de una infección viral, que incluye la infección viral de ARN, y los compuestos que pueden modular la ruta de RIG-l en las células de vertebrados, que incluyen los compuestos que pueden activar la ruta de RIG-l.
MX2014003887A 2011-09-30 2012-09-27 Compuestos antivirales. MX351818B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161542049P 2011-09-30 2011-09-30
PCT/US2012/057646 WO2013049407A2 (en) 2011-09-30 2012-09-27 Anti-viral compounds

Publications (2)

Publication Number Publication Date
MX2014003887A MX2014003887A (es) 2014-11-21
MX351818B true MX351818B (es) 2017-10-30

Family

ID=47996748

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003887A MX351818B (es) 2011-09-30 2012-09-27 Compuestos antivirales.

Country Status (16)

Country Link
US (2) US9555106B2 (es)
EP (1) EP2748172B1 (es)
JP (2) JP2014528412A (es)
KR (1) KR20140070631A (es)
CN (1) CN103857683B (es)
AP (1) AP2014007595A0 (es)
AU (3) AU2012315953A1 (es)
BR (1) BR112014007599A2 (es)
CA (1) CA2859946C (es)
HK (1) HK1199029A1 (es)
IL (1) IL231780A (es)
MX (1) MX351818B (es)
SG (1) SG11201401084TA (es)
TW (1) TW201326163A (es)
WO (1) WO2013049407A2 (es)
ZA (1) ZA201401825B (es)

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WO2013049407A2 (en) 2011-09-30 2013-04-04 Kineta, Inc Anti-viral compounds
US9073946B2 (en) 2013-01-15 2015-07-07 Kineta, Inc. Anti-viral compounds
MX2016014642A (es) * 2014-05-09 2017-05-25 Kineta Inc Compuestos y composiciones farmaceuticas antivirales, asi como metodos de uso de los mismos.
KR20200006972A (ko) 2017-04-14 2020-01-21 톨나인, 인크. 면역조절 폴리뉴클레오티드, 이의 항체 접합체, 및 이의 사용 방법
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WO2020036574A1 (en) * 2018-08-17 2020-02-20 Kineta, Inc. Activators of the retinoic acid inducible gene "rig-i' pathway and methods of use thereof
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WO2022180003A1 (en) * 2021-02-24 2022-09-01 F. Hoffmann-La Roche Ag Benzothiazolyl bicyclo[1.1.1]pentane derivatives for the treatment and prophylaxis of hepatitis b virus infection

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Also Published As

Publication number Publication date
NZ622636A (en) 2016-07-29
WO2013049407A2 (en) 2013-04-04
MX2014003887A (es) 2014-11-21
US9555106B2 (en) 2017-01-31
AU2017254812B2 (en) 2018-07-19
CA2859946A1 (en) 2013-04-04
US20170258897A1 (en) 2017-09-14
CN103857683A (zh) 2014-06-11
AP2014007595A0 (en) 2014-04-30
IL231780A0 (en) 2014-05-28
AU2012315953A1 (en) 2014-04-03
AU2017210483A1 (en) 2017-08-17
CN103857683B (zh) 2016-10-12
TW201326163A (zh) 2013-07-01
JP2017222656A (ja) 2017-12-21
KR20140070631A (ko) 2014-06-10
EP2748172A2 (en) 2014-07-02
AU2017254812A1 (en) 2017-11-16
SG11201401084TA (en) 2014-04-28
EP2748172A4 (en) 2015-10-14
IL231780A (en) 2017-08-31
US9956285B2 (en) 2018-05-01
EP2748172B1 (en) 2017-12-06
US20140227320A1 (en) 2014-08-14
BR112014007599A2 (pt) 2017-04-11
ZA201401825B (en) 2017-08-30
CA2859946C (en) 2019-11-05
WO2013049407A3 (en) 2013-05-30
JP2014528412A (ja) 2014-10-27
HK1199029A1 (en) 2015-06-19

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