MX351340B - Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este. - Google Patents

Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este.

Info

Publication number
MX351340B
MX351340B MX2014010492A MX2014010492A MX351340B MX 351340 B MX351340 B MX 351340B MX 2014010492 A MX2014010492 A MX 2014010492A MX 2014010492 A MX2014010492 A MX 2014010492A MX 351340 B MX351340 B MX 351340B
Authority
MX
Mexico
Prior art keywords
fibrinogen
production
improved process
produced
paste
Prior art date
Application number
MX2014010492A
Other languages
English (en)
Other versions
MX2014010492A (es
Inventor
Römisch Jürgen
Schulz Petra
Gehringer Werner
Schön Friedrich
Leitinger Caroline
Pape Rainer
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49160276&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX351340(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of MX2014010492A publication Critical patent/MX2014010492A/es
Publication of MX351340B publication Critical patent/MX351340B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a el proceso para purificar fibrinógeno de un fibrinógeno de una fuente que contiene fibrinógeno por precipitación de fibrinógeno por un agente de precipitación de una solución que contiene fibrinógeno en presencia de uno o más agente(s) quelante(s) y remoción del sobrenadante de la pasta de fibrinógeno, caracterizado porque el fibrinógeno se extrae de la pasta que forma una fracción líquida que contiene fibrinógeno y un residuo no disuelto, que se separa del líquido.
MX2014010492A 2012-03-13 2013-03-12 Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este. MX351340B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261610030P 2012-03-13 2012-03-13
EP12159276 2012-03-13
PCT/EP2013/054983 WO2013135684A1 (en) 2012-03-13 2013-03-12 Improved process for production of fibrinogen and fibrinogen produced thereby

Publications (2)

Publication Number Publication Date
MX2014010492A MX2014010492A (es) 2014-11-14
MX351340B true MX351340B (es) 2017-10-11

Family

ID=49160276

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014010492A MX351340B (es) 2012-03-13 2013-03-12 Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este.

Country Status (8)

Country Link
US (2) US10112972B2 (es)
EP (1) EP2825555B1 (es)
CN (1) CN104321340B (es)
AU (1) AU2013231321B2 (es)
ES (1) ES2642383T3 (es)
MX (1) MX351340B (es)
RU (1) RU2663792C2 (es)
WO (1) WO2013135684A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9371355B2 (en) 2010-09-20 2016-06-21 Octapharma Ag Process for production of fibrinogen
AU2013231321B2 (en) 2012-03-13 2017-05-25 Octapharma Ag Improved process for production of fibrinogen and fibrinogen produced thereby
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
US20140154233A1 (en) 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
CN104231072B (zh) * 2014-10-09 2017-03-22 江西博雅生物制药股份有限公司 一种从冷沉淀提取凝血因子ⅷ的废料中提取人纤维蛋白原的制备工艺
KR101841587B1 (ko) 2016-01-12 2018-05-14 주식회사 녹십자홀딩스 피브리노겐의 정제방법
CN109111043B (zh) * 2018-09-16 2021-11-09 苏州渭中科技发展有限公司 一种高盐高cod废水的处理方法
CN113214384B (zh) * 2021-04-26 2023-10-10 泰州博莱得利生物科技有限公司 犬纤维蛋白原的制备方法及其产品

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4116635A (en) 1977-03-14 1978-09-26 Jaeger Mark A General purpose in vitro anticoagulant
DE3203775A1 (de) 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
DE3230849A1 (de) 1982-08-19 1984-02-23 Behringwerke Ag, 3550 Marburg Pasteurisiertes human-fibrinogen (hf) und verfahren zu dessen herstellung
US4540573A (en) 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
FR2686883B1 (fr) 1992-02-04 1994-05-13 Aquitaine Develop Transf Sanguin Procede de fabrication de fibrinogene de tres haute purete, fibrinogene de tres haute purete obtenu ainsi qu'une composition pharmaceutique le contenant.
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
EP0748215B1 (en) 1994-02-17 2003-05-28 New York Blood Center, Inc. Biologic bioadhesive compositions containing fibrin glue and liposomes, methods of preparation and use
ES2139227T5 (es) 1994-07-14 2011-05-04 Caf-Dcf Département Central De Fractionnement De La Croix Rouge S.C.R.L. Concentrado de fibrinógeno obtenido de plasma sanguíneo, procedimiento e instalación para su preparación.
US6037457A (en) * 1997-01-31 2000-03-14 The University Of North Carolina At Chapel Hill Method for recombinant fibrinogen production
WO2000017239A1 (en) 1998-09-24 2000-03-30 Ppl Therapeutics (Scotland) Limited Purification of fibrinogen from fluids by precipitation and hydrophobic chromatography
KR100858830B1 (ko) 1998-11-18 2008-09-17 체에스엘 베링 게엠베하 조직 접합제용의 안정화된 단백질 제제
US7572769B2 (en) 1998-12-23 2009-08-11 Csl Behring Gmbh Fibrin adhesive granulate and method for its preparation
CA2362513C (en) 1999-02-12 2011-04-26 Baxter Aktiengesellschaft A method for producing a preparation based on fibrinogen and fibronectin as well as protein compositions obtainable according to this method
RU2158130C1 (ru) * 1999-12-17 2000-10-27 Нижегородское государственное предприятие по производству бактерийных препаратов фирма "ИмБио" Способ получения фибриногена
EP1250929A4 (en) 1999-12-20 2004-12-29 Mitsubishi Pharma Corp BY POROUS MEMBRANE-TREATED, VIRUS-FREE PLASMA PROTEIN COMPOUND AND ITS MANUFACTURING PROCESS
WO2001048016A1 (en) 1999-12-23 2001-07-05 Csl Limited Separation of fibrinogen from plasma proteases
EP1148063A1 (de) 2000-04-18 2001-10-24 Octapharma AG Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung
IL136552A (en) 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
IL144446A0 (en) 2001-07-19 2002-05-23 Prochon Biotech Ltd Plasma protein matrices and methods for their preparation
DE10211632A1 (de) 2002-03-15 2003-10-09 Aventis Behring Gmbh Verfahren zur Abtrennung von Viren aus einer Proteinlösung durch Nanofiltration
GB0216001D0 (en) 2002-07-10 2002-08-21 Nat Blood Authority Process and composition
DE10231757A1 (de) 2002-07-13 2004-01-22 Creavis Gesellschaft Für Technologie Und Innovation Mbh Verfahren zur Herstellung einer tensidfreien Suspension auf wässriger basis von nanostrukturierten, hydrophoben Partikeln und deren Verwendung
DE10261126A1 (de) 2002-08-13 2004-03-04 Aventis Behring Gmbh Lagerungsstabile, flüssige Fibrinogen-Formulierung
AT501088A2 (de) 2002-12-18 2006-06-15 Bio Prod & Bio Eng Ag Stabile therapeutische proteine
ES2214967B1 (es) 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
DK1888537T3 (da) 2005-05-26 2013-12-09 Janssen R & D Ireland Fremgangsmåde til fremstilling af 4[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino]benzonitril
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
US7968682B2 (en) 2006-12-12 2011-06-28 Oregon Health & Science University Degradation-resistant fibrinogen sealants
EP2293776B8 (de) 2008-06-23 2016-05-11 Bio-Products & Bio-Engineering Aktiengesellschaft Lagerstabiles, funktionell intaktes virus-inaktiviertes fibrinogen
CN101703763B (zh) 2009-11-05 2012-07-11 绿十字(中国)生物制品有限公司 人纤维蛋白原的生产方法
US9371355B2 (en) 2010-09-20 2016-06-21 Octapharma Ag Process for production of fibrinogen
AU2013231321B2 (en) 2012-03-13 2017-05-25 Octapharma Ag Improved process for production of fibrinogen and fibrinogen produced thereby
US20140154233A1 (en) 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins

Also Published As

Publication number Publication date
RU2014139974A (ru) 2016-05-10
EP2825555A1 (en) 2015-01-21
AU2013231321B2 (en) 2017-05-25
EP2825555B1 (en) 2017-07-12
US20190016755A1 (en) 2019-01-17
MX2014010492A (es) 2014-11-14
CN104321340B (zh) 2018-11-09
US10112972B2 (en) 2018-10-30
US11401300B2 (en) 2022-08-02
AU2013231321A1 (en) 2014-09-11
CN104321340A (zh) 2015-01-28
RU2663792C2 (ru) 2018-08-09
ES2642383T3 (es) 2017-11-16
US20150045539A1 (en) 2015-02-12
WO2013135684A1 (en) 2013-09-19

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