MX346749B - Uso de intercambio de medio liquido por filtracion de flujo cruzado en la preparacion de suspensiones de farmaco. - Google Patents
Uso de intercambio de medio liquido por filtracion de flujo cruzado en la preparacion de suspensiones de farmaco.Info
- Publication number
- MX346749B MX346749B MX2013008118A MX2013008118A MX346749B MX 346749 B MX346749 B MX 346749B MX 2013008118 A MX2013008118 A MX 2013008118A MX 2013008118 A MX2013008118 A MX 2013008118A MX 346749 B MX346749 B MX 346749B
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- liquid medium
- cross flow
- particles
- flow filtration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Se describe un método para hacer partículas de un fármaco, en donde se hace uso de la diafiltración; la diafiltración puede ser con un antisolvente, en cuyo caso se obtiene un precipitado de partículas como tales; la diafiltración también puede ser con un medio de suspensión farmacéuticamente aceptable; en ese caso se pueden evitar varios pasos del proceso de aislar, secar, transportar partículas, porque la suspensión que resulta de la síntesis de las partículas se dirige directamente a una formulación final del producto del fármaco.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161431942P | 2011-01-12 | 2011-01-12 | |
PCT/EP2012/050336 WO2012095439A1 (en) | 2011-01-12 | 2012-01-11 | Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013008118A MX2013008118A (es) | 2013-08-12 |
MX346749B true MX346749B (es) | 2017-03-29 |
Family
ID=45478323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013008118A MX346749B (es) | 2011-01-12 | 2012-01-11 | Uso de intercambio de medio liquido por filtracion de flujo cruzado en la preparacion de suspensiones de farmaco. |
Country Status (10)
Country | Link |
---|---|
US (1) | US9066864B2 (es) |
EP (1) | EP2663287A1 (es) |
JP (1) | JP5934719B2 (es) |
CN (1) | CN103347499B (es) |
AU (1) | AU2012206621B2 (es) |
BR (1) | BR112013016851B1 (es) |
CA (1) | CA2823972C (es) |
MX (1) | MX346749B (es) |
SG (2) | SG191963A1 (es) |
WO (1) | WO2012095439A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6478959B2 (ja) * | 2016-09-07 | 2019-03-06 | 株式会社富士薬品 | 粒子含有組成物を製造するためのシステム及び方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60019098T2 (de) | 1999-05-12 | 2006-02-02 | Metabolix, Inc., Cambridge | Verfahren zur reinigung von polyhydroxyalkanoaten |
DE69930768T2 (de) | 1999-09-17 | 2007-04-12 | Alfa Laval Nakskov A/S | Verfahren und vorrichtung zur kontinuierlichen kreuzfluss-diafiltration |
US20040256749A1 (en) * | 2000-12-22 | 2004-12-23 | Mahesh Chaubal | Process for production of essentially solvent-free small particles |
JP2005513145A (ja) * | 2001-12-21 | 2005-05-12 | セラター テクノロジーズ インコーポレイテッド | 改変されたポリマー脂質送達ビヒクル |
WO2003063877A1 (en) * | 2002-02-01 | 2003-08-07 | Akzo Nobel N.V. | Cefquinome composition for intra-mammary administration in cattle |
MXPA05004219A (es) * | 2002-10-25 | 2005-06-08 | Akzo Nobel Nv | Composicion farmaceutica de liberacion prolongada. |
ITMI20022674A1 (it) | 2002-12-18 | 2004-06-19 | Chiesi Farma Spa | Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione. |
TR201906255T4 (tr) * | 2009-12-11 | 2019-05-21 | Pfizer | Terapötik partiküllerin liyofilize edilmesine yönelik stabil formülasyonlar. |
-
2012
- 2012-01-11 MX MX2013008118A patent/MX346749B/es active IP Right Grant
- 2012-01-11 CN CN201280005390.0A patent/CN103347499B/zh active Active
- 2012-01-11 SG SG2013053764A patent/SG191963A1/en unknown
- 2012-01-11 AU AU2012206621A patent/AU2012206621B2/en active Active
- 2012-01-11 US US13/979,231 patent/US9066864B2/en active Active
- 2012-01-11 BR BR112013016851-0A patent/BR112013016851B1/pt active IP Right Grant
- 2012-01-11 SG SG10201807631SA patent/SG10201807631SA/en unknown
- 2012-01-11 CA CA2823972A patent/CA2823972C/en active Active
- 2012-01-11 JP JP2013548820A patent/JP5934719B2/ja active Active
- 2012-01-11 WO PCT/EP2012/050336 patent/WO2012095439A1/en active Application Filing
- 2012-01-11 EP EP12700273.1A patent/EP2663287A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2012206621A1 (en) | 2013-07-04 |
EP2663287A1 (en) | 2013-11-20 |
JP2014502624A (ja) | 2014-02-03 |
CA2823972C (en) | 2019-05-28 |
CA2823972A1 (en) | 2012-07-19 |
CN103347499B (zh) | 2017-04-05 |
SG10201807631SA (en) | 2018-10-30 |
WO2012095439A1 (en) | 2012-07-19 |
BR112013016851A2 (pt) | 2016-10-04 |
CN103347499A (zh) | 2013-10-09 |
SG191963A1 (en) | 2013-08-30 |
BR112013016851B1 (pt) | 2021-08-31 |
US9066864B2 (en) | 2015-06-30 |
AU2012206621B2 (en) | 2017-04-27 |
MX2013008118A (es) | 2013-08-12 |
US20130281425A1 (en) | 2013-10-24 |
JP5934719B2 (ja) | 2016-06-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1200207A1 (en) | Process line for the production of freeze-dried particles | |
SE0800304L (sv) | Förfarande för framställning av etanol utifrån sockerartshaltig lösning/suspension medelst fermentering | |
WO2014100779A8 (en) | Methods for production of platelets from pluripotent stem cells and compositions thereof | |
TN2013000411A1 (en) | Branched 3-phenylpropionic acid derivatives and the use thereof | |
WO2012094425A3 (en) | Biological methods for preparing adipic acid | |
PH12015500644A1 (en) | Novel rig-i ligands and methods for producing them | |
PL2665826T3 (pl) | Sposób fermentacyjnego wytwarzania aminokwasów zawierających siarkę | |
MX2014000753A (es) | Procedimiento para producir antigeno viral y vacunas. | |
MY180633A (en) | Solid particles, containing lactam, activator, and catalyst, method for producing said solid particles, and use of said solid particles | |
WO2012096458A3 (en) | Process for preparation of phenyl carbamate derivatives | |
EA201270409A1 (ru) | Способ производства промежуточных продуктов артемизинина | |
IT1399862B1 (it) | Macchina ad asse verticale per la produzione di sacchetti-filtro con prodotti da infusione | |
PL2797863T5 (pl) | Sposób wytwarzania 1,3-butadienu | |
EP3199518A4 (en) | Process for producing high-purity aqueous urea solution in urea production process | |
MX2013008118A (es) | Uso de intercambio de medio liquido por filtracion de flujo cruzado en la preparacion de suspensiones de farmaco. | |
WO2012166822A3 (en) | Method to produce polyhydroxyalkanoates from water-based feedstock streams | |
MY169503A (en) | Preparation method of new recombinant antibacterial polypeptide medicine | |
PL2596783T3 (pl) | Kompozycja farmaceutyczna do przygotowania roztworów preparatów przeciwdrobnoustrojowych do wlewu, sposób jej wytwarzania | |
WO2015124683A3 (de) | Filter, verwendung des filters und dessen herstellungsverfahren | |
WO2013046233A3 (en) | Process for the preparation of octreotide acetate | |
RU2012133403A (ru) | Способ получения микрокапсул лекарственных препаратов группы цефалоспоринов в конжаковой камеди в бутиловом спирте | |
JP2014502624A5 (es) | ||
WO2013080221A3 (en) | Process for alvimopan | |
CA2862520A1 (en) | Method for stereoselective synthesis of 1,4-protected 9-hydroxy-5-oxo-1,4-diaza-spiro[5.5]undecanes | |
WO2013048169A3 (en) | Method for preparing taxane derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |