MX345293B - Proceso para la preparacion de 4-amino-5-fluoro-3-halo-6-picolinat os (sustituidos). - Google Patents

Proceso para la preparacion de 4-amino-5-fluoro-3-halo-6-picolinat os (sustituidos).

Info

Publication number
MX345293B
MX345293B MX2013008605A MX2013008605A MX345293B MX 345293 B MX345293 B MX 345293B MX 2013008605 A MX2013008605 A MX 2013008605A MX 2013008605 A MX2013008605 A MX 2013008605A MX 345293 B MX345293 B MX 345293B
Authority
MX
Mexico
Prior art keywords
picolinates
halo
fluoro
amino
preparation
Prior art date
Application number
MX2013008605A
Other languages
English (en)
Other versions
MX2013008605A (es
Inventor
Zhu Yuanming
M Renga James
E Arndt Kim
L Siddall Thomas
T Whiteker Gregory
E Podhorez David
T Lowe Christian
Alan Roth Gary
P West Scott
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of MX2013008605A publication Critical patent/MX2013008605A/es
Publication of MX345293B publication Critical patent/MX345293B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/83—Thioacids; Thioesters; Thioamides; Thioimides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se preparan convenientemente 4-amino-5-fluoro-3-halo-6-picolinatos (sustituidos) a partir de 4,5,6-tricloropicolinatos por medio de una serie de etapas que incluyen intercambio de flúor, aminación, intercambio de halógeno, halogenación y acoplamiento asistido por metal de transición.
MX2013008605A 2011-01-25 2012-01-24 Proceso para la preparacion de 4-amino-5-fluoro-3-halo-6-picolinat os (sustituidos). MX345293B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161435958P 2011-01-25 2011-01-25
PCT/US2012/022291 WO2012103047A1 (en) 2011-01-25 2012-01-24 Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates

Publications (2)

Publication Number Publication Date
MX2013008605A MX2013008605A (es) 2013-08-12
MX345293B true MX345293B (es) 2017-01-24

Family

ID=46544651

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013008605A MX345293B (es) 2011-01-25 2012-01-24 Proceso para la preparacion de 4-amino-5-fluoro-3-halo-6-picolinat os (sustituidos).

Country Status (19)

Country Link
US (2) US8609855B2 (es)
EP (1) EP2667714B9 (es)
JP (1) JP5736059B2 (es)
KR (1) KR101547044B1 (es)
CN (1) CN103429081B (es)
AR (1) AR085021A1 (es)
AU (1) AU2012209283B8 (es)
BR (2) BR112013018975A2 (es)
CA (1) CA2825390A1 (es)
CO (1) CO6731130A2 (es)
IL (1) IL227648B (es)
MX (1) MX345293B (es)
PL (1) PL2667714T3 (es)
RU (1) RU2545074C1 (es)
SG (1) SG192094A1 (es)
TW (1) TWI529163B (es)
UA (1) UA109697C2 (es)
WO (1) WO2012103047A1 (es)
ZA (1) ZA201305578B (es)

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LT3460056T (lt) 2009-11-02 2020-12-28 University Of Washington Terapinės nukleazės kompozicijos ir būdai
US8774158B2 (en) 2010-09-02 2014-07-08 Intel Corporation Method and apparatus to shorten the duration of initial network selection and handover decisions in multicomm platforms by utilizing alternate fragmented scanning
TWI596088B (zh) * 2011-01-25 2017-08-21 陶氏農業科學公司 ４－胺基－６－（經取代的苯基）吡啶甲酸酯及６－胺基－２－（經取代的苯基）－４－嘧啶羧酸酯之芳烷酯以及其等作為除草劑之用途
KR102596953B1 (ko) 2011-04-29 2023-11-02 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 치료적 뉴클레아제 조성물 및 방법
AR091856A1 (es) 2012-07-24 2015-03-04 Dow Agrosciences Llc Proceso para la preparacion de 4-amino-5-fluor-3-halo-6-(substituido) picolinatos
AR092355A1 (es) 2012-07-24 2015-04-15 Dow Agrosciences Llc Fluoruros de fluoropicolinoilo y procesos para su preparacion
TW201427596A (zh) * 2012-08-07 2014-07-16 Dow Agrosciences Llc 除草性組成物
JP6239003B2 (ja) * 2012-12-13 2017-11-29 ダウ アグロサイエンシィズ エルエルシー ４−アミノ−５−フルオロ−３−クロロ−６−（置換）ピコリネートの調製方法
BR102013032078A2 (pt) * 2012-12-13 2014-10-21 Dow Agrosciences Llc Processos para a preparação de 4-amino-3-halo-6-(substituído)picolinatos e 4-amino-5-fluoro-3-halo-6-(substituído)picolinatos
US20140170058A1 (en) * 2012-12-13 2014-06-19 Dow Agrosciences Llc Process for the removal of palladium from 4-amino-3-halo-5-fluoro-6-(aryl) pyridine-2-carboxylates and 4-amino-3-halo-6-(aryl)pyridine-2-carboxylates
CA2895180A1 (en) * 2012-12-13 2014-06-19 Dow Agrosciences Llc Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates
EP2967057B1 (en) * 2013-03-15 2018-11-21 Dow AgroSciences LLC Novel 4-aminopyridine and 6-aminopyrimidine carboxylates as herbicides
TW201609651A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程（一）
BR102014028164A2 (pt) * 2013-11-12 2015-09-08 Dow Agrosciences Llc processo para fluoração de compostos
TW201609652A (zh) * 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程（三）
US9603364B2 (en) * 2013-12-12 2017-03-28 Dow Agrosciences Llc 4-amino-6-(halo-substituted-alkyl)-picolinates and their use as herbicides
CA2957187A1 (en) 2014-08-06 2016-02-11 Dow Agrosciences Llc Process for the preparation of 4,5,6-trichloropicolinic acid
TWI726900B (zh) 2015-08-04 2021-05-11 美商陶氏農業科學公司 用於氟化化合物之過程
WO2017201377A1 (en) * 2016-05-19 2017-11-23 Dow Agrosciences Llc Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
WO2018111639A1 (en) * 2016-12-13 2018-06-21 Dow Agrosciences Llc Method of preparing benzy 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate
KR102627532B1 (ko) * 2018-02-02 2024-01-19 칸토 덴카 코교 가부시키가이샤 수소 및 불소 및/또는 염소를 함유한 부타디엔 골격을 갖는 화합물의 제조 방법
EP3853205A1 (en) 2018-09-19 2021-07-28 Corteva Agriscience LLC Preparation of halogen analogs of picloram
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EP4121414A1 (en) 2020-03-18 2023-01-25 Corteva Agriscience LLC Improved synthesis of 4-amino-6-(heterocyclic)picolinates

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Also Published As

Publication number Publication date
US8609855B2 (en) 2013-12-17
PL2667714T3 (pl) 2017-08-31
TW201249799A (en) 2012-12-16
UA109697C2 (uk) 2015-09-25
EP2667714A4 (en) 2014-07-30
EP2667714A1 (en) 2013-12-04
AU2012209283B2 (en) 2015-10-29
KR20130121949A (ko) 2013-11-06
TWI529163B (zh) 2016-04-11
AR085021A1 (es) 2013-08-07
MX2013008605A (es) 2013-08-12
JP5736059B2 (ja) 2015-06-17
US20120190860A1 (en) 2012-07-26
AU2012209283B8 (en) 2015-11-05
CO6731130A2 (es) 2013-08-15
EP2667714B1 (en) 2017-03-01
IL227648B (en) 2019-01-31
ZA201305578B (en) 2014-09-25
BR102012001633A2 (pt) 2014-01-28
BR112013018975A2 (pt) 2016-07-12
US20140039196A1 (en) 2014-02-06
CA2825390A1 (en) 2012-08-02
CN103429081A (zh) 2013-12-04
WO2012103047A1 (en) 2012-08-02
EP2667714B9 (en) 2017-06-21
KR101547044B1 (ko) 2015-08-24
RU2545074C1 (ru) 2015-03-27
US8927731B2 (en) 2015-01-06
RU2013139338A (ru) 2015-03-10
CN103429081B (zh) 2016-07-20
IL227648A0 (en) 2013-09-30
AU2012209283A8 (en) 2015-11-05
SG192094A1 (en) 2013-08-30
JP2014508143A (ja) 2014-04-03

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