MX344069B - Vacuna vectorizada por el herpesvirus de los pavos contra la influenza aviar en aves de corral. - Google Patents
Vacuna vectorizada por el herpesvirus de los pavos contra la influenza aviar en aves de corral.Info
- Publication number
- MX344069B MX344069B MX2013004303A MX2013004303A MX344069B MX 344069 B MX344069 B MX 344069B MX 2013004303 A MX2013004303 A MX 2013004303A MX 2013004303 A MX2013004303 A MX 2013004303A MX 344069 B MX344069 B MX 344069B
- Authority
- MX
- Mexico
- Prior art keywords
- poultry
- avian influenza
- turkeys
- against avian
- vector
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 6
- 241001502481 Meleagrid alphaherpesvirus 1 Species 0.000 title abstract 5
- 208000002979 Influenza in Birds Diseases 0.000 title abstract 3
- 206010064097 avian influenza Diseases 0.000 title abstract 3
- 244000144977 poultry Species 0.000 title abstract 3
- 239000013598 vector Substances 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101150076489 B gene Proteins 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 239000013603 viral vector Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a al campo de las vacunas veterinarias, en particular de las vacunas para aves de corral contra la influenza aviar; la vacuna se basa en un vector viral recombinante que expresa la proteína hemaglutinina de un virus de la influenza, en donde el vector es un herpesvirus de los pavos (HVT) y el gen de hemaglutinina es activado por un promotor del gen de la glucoproteína B de un herpesvirus de mamífero; una vacuna que comprende el vector HVT-f HA puede utilizarse para inducir una respuesta inmune protectora contra la influenza aviar en aves de corral, y para reducir la dispersión del AIV; la invención también se relaciona con métodos, usos y vacunas que involucran el vector HVT+HA.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10187948 | 2010-10-18 | ||
US40772410P | 2010-10-28 | 2010-10-28 | |
PCT/EP2011/068073 WO2012052384A1 (en) | 2010-10-18 | 2011-10-17 | Herpesvirus of turkeys vectored vaccine against avian influenza in poultry |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013004303A MX2013004303A (es) | 2013-05-30 |
MX344069B true MX344069B (es) | 2016-12-02 |
Family
ID=43587599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013004303A MX344069B (es) | 2010-10-18 | 2011-10-17 | Vacuna vectorizada por el herpesvirus de los pavos contra la influenza aviar en aves de corral. |
Country Status (8)
Country | Link |
---|---|
US (1) | US8986987B2 (es) |
EP (1) | EP2629794B1 (es) |
CN (1) | CN103370079B (es) |
ES (1) | ES2635019T3 (es) |
HU (1) | HUE033739T2 (es) |
MX (1) | MX344069B (es) |
PL (1) | PL2629794T3 (es) |
WO (1) | WO2012052384A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103667351B (zh) * | 2012-09-10 | 2017-01-25 | 中国农业科学院哈尔滨兽医研究所 | 以鸭病毒性肠炎病毒疫苗株为载体的重组病毒疫苗在鸡形目禽类中的应用 |
WO2015023461A2 (en) * | 2013-08-06 | 2015-02-19 | The Trustees Of The University Of Pennsylvania | Influenza nucleic acid molecules and vaccines made therefrom |
CN106031793B (zh) * | 2015-03-13 | 2020-12-01 | 普莱柯生物工程股份有限公司 | 一种活疫苗及其制备方法和应用 |
MX2018001815A (es) * | 2015-08-10 | 2018-09-06 | Texas A & M Univ Sys | Vacunas de herpesvirus de pavo recombiante y uso de las mismas. |
MX2018015756A (es) | 2016-06-17 | 2019-05-30 | Intervet Int Bv | Construcciones de virus de la enfermedad de marek recombinantes no patogenicas codificadoras de antigenos del virus de la laringotraqueitis infecciosa y del virus de la enfermedad bursal infecciosa. |
JOP20190088A1 (ar) * | 2016-10-21 | 2019-04-21 | Us Agriculture | نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها |
CN106497893A (zh) * | 2016-10-28 | 2017-03-15 | 扬州大学 | 表达H7N9亚型禽流感病毒嵌合型血凝素蛋白的重组火鸡疱疹病毒株rHMW及构建方法 |
CN106399267A (zh) * | 2016-10-28 | 2017-02-15 | 扬州大学 | 表达H7N9亚型禽流感病毒血凝素蛋白的重组火鸡疱疹病毒株rHOH及构建方法 |
CN107296956A (zh) * | 2017-06-29 | 2017-10-27 | 青岛易邦生物工程有限公司 | 一种基因重组活载体疫苗 |
CN109666656A (zh) * | 2019-01-23 | 2019-04-23 | 北京市农林科学院 | 一种纯化重组鸡传染性法氏囊病毒vp2基因的马立克氏病病毒cvi988株的方法 |
CN110205308A (zh) * | 2019-05-24 | 2019-09-06 | 华南农业大学 | 一种表达ha基因的重组火鸡疱疹病毒及其应用 |
CN114828882A (zh) | 2019-12-20 | 2022-07-29 | 英特维特国际股份有限公司 | 多价hvt载体疫苗 |
WO2022049276A1 (en) | 2020-09-07 | 2022-03-10 | Intervet International B.V. | Ha stem vaccine for ha antibody-positive targets |
US20240058436A1 (en) | 2020-12-24 | 2024-02-22 | Intervet Inc. | Multivalent hvt vector vaccine |
JP2024525697A (ja) | 2021-07-13 | 2024-07-12 | インターベット インターナショナル ベー. フェー. | 鳥類における抗体干渉の克服 |
WO2023213946A1 (en) | 2022-05-05 | 2023-11-09 | Intervet International B.V. | New multivalent hvt vector vaccine |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5961982A (en) | 1985-09-06 | 1999-10-05 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
US5928648A (en) * | 1985-09-06 | 1999-07-27 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
ATE164885T1 (de) | 1986-01-27 | 1998-04-15 | Syntro Corp | Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten |
US5731188A (en) * | 1986-11-20 | 1998-03-24 | Syntro Corporation | Recombinant equine herpesviruses |
ES2068989T3 (es) | 1989-02-04 | 1995-05-01 | Akzo Nobel Nv | Tocoles como adyuvante en vacunas. |
US5919461A (en) * | 1989-10-18 | 1999-07-06 | Akzo Nobel N.V. | Nonpathogenic infectious bursal disease virus and vaccine |
ES2070997T3 (es) * | 1989-12-04 | 1995-06-16 | Akzo Nobel Nv | Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. |
US5690939A (en) * | 1991-05-14 | 1997-11-25 | Akzo Nobel N.V. | Recombinant vaccine against marek's disease |
ZA923041B (en) * | 1991-05-14 | 1993-04-28 | Akzo Nv | Recombinant vaccine against marek's disease |
US6183753B1 (en) * | 1994-08-09 | 2001-02-06 | Schering-Plough Veterinary Corp. | Recombinant chimeric virus and uses thereof |
US5853733A (en) * | 1993-02-26 | 1998-12-29 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
US6913751B2 (en) * | 1992-06-12 | 2005-07-05 | Schering-Plough Veterinary Corporation | Recombinant avian herpesvirus useful in vaccine production |
US5741696A (en) * | 1992-08-07 | 1998-04-21 | Syntro Corporation | Recombinant equine herpesviruses |
US6984728B2 (en) * | 1993-09-24 | 2006-01-10 | Schering Corporation | Recombinant infectious laryngotracheitis virus and uses thereof |
DK0775746T3 (da) | 1995-07-03 | 2006-04-03 | Akzo Nobel Nv | Vaccine mod fjerkræcoccidiose |
AU710080B2 (en) * | 1995-07-07 | 1999-09-16 | Nippon Zeon Co., Ltd. | Marek's disease virus genes and their use in vaccines for protection against Marek's disease |
DE69731016T2 (de) | 1996-03-04 | 2005-10-06 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Herstellung einer Trehalulose enthaltende Polysaccharidzusammensetzung. |
BR9912626B1 (pt) * | 1998-07-31 | 2010-09-08 | vacina, e, processo para atenuar geneticamente o ehv-1. | |
WO2000037101A1 (en) | 1998-12-21 | 2000-06-29 | Akzo Nobel N.V. | Method to produce inactivated w/o emulsion adjuvated vaccines |
US6299882B1 (en) * | 1999-04-09 | 2001-10-09 | Schering Corporation | UL54.5 of Marek's disease virus (MDV) |
AU6698900A (en) * | 1999-07-16 | 2001-02-05 | Agricultural Research Service | Live recombinant vaccine against avian leukosis virus using a marek's disease virus (mdv) virus as vector |
US7314715B2 (en) * | 2001-06-14 | 2008-01-01 | Schering-Plough Animal Health Corporation | Recombinant avian herpesvirus useful in vaccine production |
WO2007022151A2 (en) | 2005-08-15 | 2007-02-22 | Vaxin, Inc. | Immunization of avians by administration of non-replicating vectored vaccines |
US20080241188A1 (en) * | 2007-03-30 | 2008-10-02 | Zeon Corporation | Turkey herpesvirus vectored recombinant containing avian influenza genes |
BRPI0913216A2 (pt) | 2008-06-23 | 2016-01-19 | Intervet Int Bv | uso de um herpesvírus recombinante de perus, e, herpesvírus recombinante de perus. |
US8394384B2 (en) * | 2008-11-28 | 2013-03-12 | Merial Limited | Recombinant avian influenza vaccine and uses thereof |
CN105567648B (zh) | 2009-04-15 | 2019-09-03 | 法国诗华大药厂 | 用于免疫接种水禽物种的重组禽疱疹病毒载体和疫苗 |
-
2011
- 2011-10-17 HU HUE11771123A patent/HUE033739T2/en unknown
- 2011-10-17 WO PCT/EP2011/068073 patent/WO2012052384A1/en active Application Filing
- 2011-10-17 EP EP11771123.4A patent/EP2629794B1/en active Active
- 2011-10-17 CN CN201180061002.6A patent/CN103370079B/zh active Active
- 2011-10-17 US US13/879,822 patent/US8986987B2/en active Active
- 2011-10-17 PL PL11771123T patent/PL2629794T3/pl unknown
- 2011-10-17 MX MX2013004303A patent/MX344069B/es active IP Right Grant
- 2011-10-17 ES ES11771123.4T patent/ES2635019T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
US8986987B2 (en) | 2015-03-24 |
CN103370079B (zh) | 2016-08-10 |
CN103370079A (zh) | 2013-10-23 |
US20130230556A1 (en) | 2013-09-05 |
HUE033739T2 (en) | 2018-01-29 |
EP2629794A1 (en) | 2013-08-28 |
MX2013004303A (es) | 2013-05-30 |
PL2629794T3 (pl) | 2017-10-31 |
EP2629794B1 (en) | 2017-06-07 |
ES2635019T3 (es) | 2017-10-02 |
WO2012052384A1 (en) | 2012-04-26 |
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