MX2023012728A - Esteroide neuroactivo para el tratamiento del trastorno depresivo mayor y la depresion posparto en una mujer lactante. - Google Patents
Esteroide neuroactivo para el tratamiento del trastorno depresivo mayor y la depresion posparto en una mujer lactante.Info
- Publication number
- MX2023012728A MX2023012728A MX2023012728A MX2023012728A MX2023012728A MX 2023012728 A MX2023012728 A MX 2023012728A MX 2023012728 A MX2023012728 A MX 2023012728A MX 2023012728 A MX2023012728 A MX 2023012728A MX 2023012728 A MX2023012728 A MX 2023012728A
- Authority
- MX
- Mexico
- Prior art keywords
- depressive disorder
- major depressive
- subject
- postpartum depression
- neuroactive steroid
- Prior art date
Links
- 201000009916 Postpartum depression Diseases 0.000 title abstract 3
- 208000024714 major depressive disease Diseases 0.000 title abstract 3
- 150000003431 steroids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
La presente descripción se refiere a métodos para tratar la depresión pos-parto (PPD) en una mujer durante el período pos-natal de la mujer, el método está que comprende administrar a la mujer una cantidad terapéuticamente eficaz del Compuesto (1), o una sal farmacéuticamente aceptable del mismo, durante un período de tratamiento, en donde la mujer amamanta a un niño durante el período de tratamiento. La descripción también se refiere a métodos para tratar el trastorno depresivo mayor (MDD) en una mujer, el método está que comprende administrar a la mujer una cantidad terapéuticamente eficaz del Compuesto (1), o una sal farmacéuticamente aceptable del mismo, durante un período de tratamiento, en donde la mujer amamanta a un niño durante el período de tratamiento.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163181807P | 2021-04-29 | 2021-04-29 | |
| PCT/US2022/026908 WO2022232494A1 (en) | 2021-04-29 | 2022-04-29 | Neuroactive steroid for use in treating major depressive disorder and postpartum depression in a lactating female |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023012728A true MX2023012728A (es) | 2023-11-08 |
Family
ID=81748326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023012728A MX2023012728A (es) | 2021-04-29 | 2022-04-29 | Esteroide neuroactivo para el tratamiento del trastorno depresivo mayor y la depresion posparto en una mujer lactante. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240216396A1 (es) |
| EP (1) | EP4329769A1 (es) |
| JP (1) | JP2024515830A (es) |
| CN (1) | CN117580580A (es) |
| AU (1) | AU2022267304A1 (es) |
| CA (1) | CA3217866A1 (es) |
| IL (1) | IL307980A (es) |
| MX (1) | MX2023012728A (es) |
| WO (1) | WO2022232494A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US10774108B2 (en) | 2014-11-27 | 2020-09-15 | Sage Therapeutics, Inc. | Compositions and methods for treating CNS disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9512165B2 (en) | 2013-04-17 | 2016-12-06 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof |
| AU2017315682B2 (en) | 2016-08-23 | 2021-11-11 | Sage Therapeutics, Inc. | A crystalline 19-nor C3, 3-disubstituted C21-n-pyrazolyl steroid |
| JP2021527092A (ja) * | 2018-06-12 | 2021-10-11 | セージ セラピューティクス， インコーポレイテッド | １９−ノルｃ３，３−二置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| JP2022514510A (ja) * | 2018-12-14 | 2022-02-14 | プラクシス プレシジョン メディスンズ，インコーポレイテッド | うつ病の治療方法 |
| US20230285417A1 (en) | 2020-07-20 | 2023-09-14 | Sage Therapeutics, Inc. | Formulations of 19-nor c3,3-disubstituted c21-n-pyrazolyl steroid and methods of use thereof |
-
2022
- 2022-04-29 WO PCT/US2022/026908 patent/WO2022232494A1/en active Application Filing
- 2022-04-29 AU AU2022267304A patent/AU2022267304A1/en active Pending
- 2022-04-29 CA CA3217866A patent/CA3217866A1/en active Pending
- 2022-04-29 IL IL307980A patent/IL307980A/en unknown
- 2022-04-29 EP EP22724194.0A patent/EP4329769A1/en active Pending
- 2022-04-29 JP JP2023566515A patent/JP2024515830A/ja active Pending
- 2022-04-29 CN CN202280045723.6A patent/CN117580580A/zh active Pending
- 2022-04-29 MX MX2023012728A patent/MX2023012728A/es unknown
- 2022-04-29 US US18/557,705 patent/US20240216396A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240216396A1 (en) | 2024-07-04 |
| AU2022267304A1 (en) | 2023-11-02 |
| CA3217866A1 (en) | 2022-11-03 |
| JP2024515830A (ja) | 2024-04-10 |
| WO2022232494A1 (en) | 2022-11-03 |
| IL307980A (en) | 2023-12-01 |
| CN117580580A (zh) | 2024-02-20 |
| EP4329769A1 (en) | 2024-03-06 |
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