MX2023002421A - Variantes de amilasa modificadas geneticamente. - Google Patents

Variantes de amilasa modificadas geneticamente.

Info

Publication number
MX2023002421A
MX2023002421A MX2023002421A MX2023002421A MX2023002421A MX 2023002421 A MX2023002421 A MX 2023002421A MX 2023002421 A MX2023002421 A MX 2023002421A MX 2023002421 A MX2023002421 A MX 2023002421A MX 2023002421 A MX2023002421 A MX 2023002421A
Authority
MX
Mexico
Prior art keywords
engineered
amylase polypeptides
amylase variants
amylase
compositions
Prior art date
Application number
MX2023002421A
Other languages
English (en)
Inventor
Nikki Dellas
Ravi David Garcia
Harvinder Chagger Maniar
Chinping Chng
Da Duan
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of MX2023002421A publication Critical patent/MX2023002421A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención proporciona polipéptidos de amilasa modificados genéticamente y composiciones de los mismos; los polipéptidos de amilasa diseñados genéticamente se han optimizado para proporcionar termoestabilidad, estabilidad de proteasa y estabilidad mejoradas en una variedad de condiciones de pH, incluidas condiciones ácidas (pH.
MX2023002421A 2020-08-28 2021-08-27 Variantes de amilasa modificadas geneticamente. MX2023002421A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063071641P 2020-08-28 2020-08-28
PCT/US2021/048108 WO2022047264A1 (en) 2020-08-28 2021-08-27 Engineered amylase variants

Publications (1)

Publication Number Publication Date
MX2023002421A true MX2023002421A (es) 2023-05-18

Family

ID=80354112

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002421A MX2023002421A (es) 2020-08-28 2021-08-27 Variantes de amilasa modificadas geneticamente.

Country Status (11)

Country Link
US (2) US11767519B2 (es)
EP (1) EP4204552A1 (es)
JP (1) JP2023539634A (es)
KR (1) KR20230145027A (es)
CN (1) CN116897205A (es)
AU (1) AU2021331493A1 (es)
BR (1) BR112023003643A2 (es)
CA (1) CA3191900A1 (es)
IL (1) IL300533A (es)
MX (1) MX2023002421A (es)
WO (1) WO2022047264A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

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Also Published As

Publication number Publication date
JP2023539634A (ja) 2023-09-15
US20220090038A1 (en) 2022-03-24
CA3191900A1 (en) 2022-03-03
KR20230145027A (ko) 2023-10-17
WO2022047264A1 (en) 2022-03-03
BR112023003643A2 (pt) 2023-03-28
AU2021331493A1 (en) 2023-03-09
US11767519B2 (en) 2023-09-26
IL300533A (en) 2023-04-01
CN116897205A (zh) 2023-10-17
US20240026326A1 (en) 2024-01-25
EP4204552A1 (en) 2023-07-05

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