MX2023001557A - Sistemas y metodos para la eliminacion de conservantes de formulaciones oftalmaticas. - Google Patents

Sistemas y metodos para la eliminacion de conservantes de formulaciones oftalmaticas.

Info

Publication number
MX2023001557A
MX2023001557A MX2023001557A MX2023001557A MX2023001557A MX 2023001557 A MX2023001557 A MX 2023001557A MX 2023001557 A MX2023001557 A MX 2023001557A MX 2023001557 A MX2023001557 A MX 2023001557A MX 2023001557 A MX2023001557 A MX 2023001557A
Authority
MX
Mexico
Prior art keywords
preservative
systems
methods
ophthalmic formulations
emulsion
Prior art date
Application number
MX2023001557A
Other languages
English (en)
Inventor
Michael Williams
Michael T Malanga
Srini Venkatesh
Original Assignee
Tearclear Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tearclear Corp filed Critical Tearclear Corp
Publication of MX2023001557A publication Critical patent/MX2023001557A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • B01D69/147—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes containing embedded adsorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28047—Gels

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

En el presente documento se describen sistemas y métodos para eliminar un conservante de una solución, emulsión o suspensión que comprende un agente oftálmico. Dichos sistemas comprenden una matriz polimérica que elimina los conservantes que comprende un componente de matriz activo y un componente de matriz inactivo. Un método para administrar un agente oftálmico comprende proporcionar una solución, emulsión o suspensión que comprende un agente oftálmico y un conservante; y proporcionar una matriz polimérica que elimina el conservante que comprende un componente de matriz activo y un componente de matriz inactivo, y en donde la matriz polimérica está configurada para absorber selectivamente el conservante cuando la solución, emulsión o suspensión pasa a través de ella.
MX2023001557A 2020-08-05 2021-08-04 Sistemas y metodos para la eliminacion de conservantes de formulaciones oftalmaticas. MX2023001557A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063061561P 2020-08-05 2020-08-05
PCT/US2021/044533 WO2022031841A1 (en) 2020-08-05 2021-08-04 Systems and methods for preservative removal from ophthalmic formulations

Publications (1)

Publication Number Publication Date
MX2023001557A true MX2023001557A (es) 2023-03-08

Family

ID=80114633

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023001557A MX2023001557A (es) 2020-08-05 2021-08-04 Sistemas y metodos para la eliminacion de conservantes de formulaciones oftalmaticas.

Country Status (10)

Country Link
US (2) US11478378B2 (es)
EP (1) EP4192405A1 (es)
JP (1) JP2023536900A (es)
KR (1) KR20230071121A (es)
CN (1) CN116322597A (es)
AU (1) AU2021322232A1 (es)
CA (1) CA3188012A1 (es)
IL (1) IL300333A (es)
MX (1) MX2023001557A (es)
WO (1) WO2022031841A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11723838B2 (en) 2019-05-02 2023-08-15 TearClear Corp. Preservative removal from eye drops
WO2022031841A1 (en) 2020-08-05 2022-02-10 TearClear Corp. Systems and methods for preservative removal from ophthalmic formulations

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3293112A (en) 1963-05-06 1966-12-20 Grace W R & Co Amino-cross linked oxidized alpha-olefin polymer
US3322711A (en) 1963-10-17 1967-05-30 Allied Chem Polymer oxidation process and emulsion therefrom
DE1570652A1 (de) 1964-03-09 1970-03-26 Allied Chem Verfahren zur Herstellung von oxydiertem Polyaethylen
DE3112163A1 (de) 1981-03-27 1982-10-14 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von emulgierbarem polyethylen durch oxidation von polyethylen im wirbelbettreaktor
DE3720953A1 (de) 1987-06-25 1989-01-05 Basf Ag Verfahren zur oxidation von polyethylen
US5080800A (en) 1990-01-08 1992-01-14 Ciba-Geigy Corporation Process for removing components from solutions
US5056689A (en) 1990-01-08 1991-10-15 Ciba-Geigy Corporation Apparatus for removing components from solutions
US5401811A (en) 1994-05-03 1995-03-28 Eastman Chemical Company Continuous process for the oxidation of polyethylene
WO2005066219A1 (en) 2003-04-01 2005-07-21 Honeywell International Inc. Process for oxidizing linear low molecular weight polyethylene
US7622031B2 (en) 2007-01-15 2009-11-24 Honeywell International Inc Method for preparing oxidized polyolefin waxes
US20100285192A1 (en) 2008-01-29 2010-11-11 Universite Catholique De Louvain Method for filtering a liquid
EP2435526A4 (en) 2009-05-29 2012-10-31 Exxonmobil Chem Patents Inc POLYOLEFINIC ADHESIVE COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME
JP5923942B2 (ja) 2011-11-18 2016-05-25 日立化成株式会社 半導体封止用エポキシ樹脂組成物およびそれを用いた半導体装置
GB2544213B (en) * 2014-08-13 2017-09-27 Univ Florida Preservative removal from eye drops
AU2015353701B2 (en) * 2014-11-25 2021-03-25 Allergan, Inc. Stabilized omega-3 ophthalmic compositions
AU2017366761B2 (en) 2016-12-02 2023-06-15 University Of Florida Research Foundation, Inc. Preservative removal from eye drops
CN116392389A (zh) 2017-09-25 2023-07-07 佛罗里达大学研究基金会股份有限公司 从含亲水药物的滴眼剂中除去防腐剂
TW202005623A (zh) * 2018-04-06 2020-02-01 美商蒂克利爾公司 用於輸送治療劑之系統及方法
JP2022519580A (ja) * 2019-02-06 2022-03-24 ティアークリアー コープ． 複合体化剤を含む眼科用製剤から防腐剤を除去するためのシステムおよび方法
US11723838B2 (en) 2019-05-02 2023-08-15 TearClear Corp. Preservative removal from eye drops
WO2022031841A1 (en) 2020-08-05 2022-02-10 TearClear Corp. Systems and methods for preservative removal from ophthalmic formulations

Also Published As

Publication number Publication date
JP2023536900A (ja) 2023-08-30
US11478378B2 (en) 2022-10-25
WO2022031841A1 (en) 2022-02-10
KR20230071121A (ko) 2023-05-23
CN116322597A (zh) 2023-06-23
AU2021322232A1 (en) 2023-03-23
US20220409430A1 (en) 2022-12-29
IL300333A (en) 2023-04-01
CA3188012A1 (en) 2022-02-10
EP4192405A1 (en) 2023-06-14
US20220039997A1 (en) 2022-02-10

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