MX2023001120A - Composicion farmaceutica que comprende una celula que expresa un receptor quimerico. - Google Patents

Composicion farmaceutica que comprende una celula que expresa un receptor quimerico.

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Publication number
MX2023001120A
MX2023001120A MX2023001120A MX2023001120A MX2023001120A MX 2023001120 A MX2023001120 A MX 2023001120A MX 2023001120 A MX2023001120 A MX 2023001120A MX 2023001120 A MX2023001120 A MX 2023001120A MX 2023001120 A MX2023001120 A MX 2023001120A
Authority
MX
Mexico
Prior art keywords
chimeric receptor
pharmaceutical composition
immunoreceptor
extracellular domain
composition including
Prior art date
Application number
MX2023001120A
Other languages
English (en)
Inventor
Shun Shimizu
Kanako Tatsumi
Mika Sakurai
Koji Tamada
Yukimi Sakoda
Takashi Suzuki
Tomoyuki Igawa
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2023001120A publication Critical patent/MX2023001120A/es

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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Abstract

La presente invención se refiere a una composición farmacéutica que comprende células que expresan un receptor quimérico, para uso en combinación con la administración de una molécula de unión al antígeno, en donde el receptor quimérico comprende un dominio extracelular, el dominio extracelular comprende un dominio extracelular de un inmunorreceptor, una variante del dominio extracelular de un inmunorreceptor, o una porción del mismo, y la molécula de unión al antígeno es una molécula de unión al antígeno multiespecífica que tiene un sitio de reconocimiento al antígeno y un sitio de reconocimiento del inmunorreceptor el cual reconoce el inmunorreceptor.
MX2023001120A 2020-07-31 2021-07-30 Composicion farmaceutica que comprende una celula que expresa un receptor quimerico. MX2023001120A (es)

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IL300225A (en) 2023-03-01
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US20230322898A1 (en) 2023-10-12
TW202220677A (zh) 2022-06-01
BR112023000537A2 (pt) 2023-01-31
AU2021317974A1 (en) 2023-03-16
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CA3190649A1 (en) 2022-02-03
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