MX2022006229A - Composiciones y metodos para el tratamiento de resistencia a la insulina. - Google Patents

Composiciones y metodos para el tratamiento de resistencia a la insulina.

Info

Publication number
MX2022006229A
MX2022006229A MX2022006229A MX2022006229A MX2022006229A MX 2022006229 A MX2022006229 A MX 2022006229A MX 2022006229 A MX2022006229 A MX 2022006229A MX 2022006229 A MX2022006229 A MX 2022006229A MX 2022006229 A MX2022006229 A MX 2022006229A
Authority
MX
Mexico
Prior art keywords
insulin resistance
treatment
compositions
methods
insulin
Prior art date
Application number
MX2022006229A
Other languages
English (en)
Inventor
Salim Merali
Carlos A Barrero
Wayne E Childers
George C Morton
Original Assignee
Univ Temple
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Temple filed Critical Univ Temple
Publication of MX2022006229A publication Critical patent/MX2022006229A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Abstract

Los compuestos de la fórmula I, y sales farmacéuticamente efectivas del mismo (ver Fórmula) en donde R1 - R14, m, n, o, p, q y r son como se definen en la presente, se proporcionan para el tratamiento de incrementar la sensibilidad a la insulina, reducir la resistencia a la insulina, prevenir la resistencia a la insulina y tratar los trastornos de resistencia a la insulina.
MX2022006229A 2016-09-07 2019-03-06 Composiciones y metodos para el tratamiento de resistencia a la insulina. MX2022006229A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662384390P 2016-09-07 2016-09-07

Publications (1)

Publication Number Publication Date
MX2022006229A true MX2022006229A (es) 2022-06-22

Family

ID=61561578

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019002607A MX2019002607A (es) 2016-09-07 2017-09-07 Composiciones y metodos para el tratamiento de resistencia a la insulina.
MX2022006229A MX2022006229A (es) 2016-09-07 2019-03-06 Composiciones y metodos para el tratamiento de resistencia a la insulina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2019002607A MX2019002607A (es) 2016-09-07 2017-09-07 Composiciones y metodos para el tratamiento de resistencia a la insulina.

Country Status (10)

Country Link
US (2) US10729670B2 (es)
EP (1) EP3509575A4 (es)
JP (1) JP7235312B2 (es)
CN (1) CN110139644B (es)
AU (2) AU2017324510B2 (es)
BR (1) BR112019004405A2 (es)
CA (1) CA3035972A1 (es)
MX (2) MX2019002607A (es)
WO (1) WO2018049019A1 (es)
ZA (1) ZA201902155B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10729670B2 (en) * 2016-09-07 2020-08-04 Temple University—Of The Commonwealth Systems Of Higher Education Compositions and methods for treatment of insulin resistance
WO2019173633A1 (en) * 2018-03-07 2019-09-12 Temple University - Of The Commonwealth System Of Higher Education Compositions and methods for treatment of insulin resistance
EP3761984A4 (en) * 2018-03-07 2021-12-22 Temple University - Of The Commonwealth System of Higher Education COMPOSITIONS AND METHODS OF TREATMENT FOR INSULIN RESISTANCE
TW202206062A (zh) 2020-04-24 2022-02-16 美國坦普大學 高等教育聯邦系統 治療非酒精性脂肪肝炎的方法

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US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
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US5344846A (en) 1992-12-30 1994-09-06 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
IT1283218B1 (it) * 1996-03-08 1998-04-16 Bracco Spa Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi
IL140844A0 (en) 2001-01-10 2002-02-10 Polygene Ltd Cationic polysaccharide compositions
US7135575B2 (en) * 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
US20080260703A1 (en) 2007-04-23 2008-10-23 Medistem Labortories Treatment of Insulin Resistance and Diabetes
SI2252312T1 (sl) 2008-02-07 2014-08-29 Cornell University, Postopki za preprečevanje ali zdravljenje insulinske rezistence
WO2011083150A2 (en) * 2010-01-07 2011-07-14 Akron Molecules Gmbh Obesity small molecules
JP6116568B2 (ja) 2011-08-30 2017-04-19 アカデミッシュ メディッシュ セントラム インスリン抵抗性を予防および／または処置する方法
PT2768314E (pt) 2011-10-18 2016-02-17 Nestec Sa Composição para utilização no aumento de sensibilidade à insulina e/ou redução da resistência à insulina
WO2015187942A1 (en) 2014-06-04 2015-12-10 Case Western Reserve University Compositions and methods of treating diabetic retinopathy
EP2909216B1 (en) 2012-10-17 2016-12-21 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Compositions and methods for improving glucose uptake
US20150182483A1 (en) * 2014-01-02 2015-07-02 Joel Steven Goldberg Glycation of l-lysine to lower blood glucose and treat complications of diabetes
CN103833623B (zh) * 2014-03-03 2016-07-06 河南大学 一种氨基酸-胺缀合物及其制备方法和应用
WO2015161448A1 (en) * 2014-04-22 2015-10-29 Wuhan Ll Science And Technology Development Co., Ltd. Ornithine-containing or aspartate-containing compositions and the uses thereof
WO2017044933A1 (en) 2015-09-13 2017-03-16 The Research Foundation for State University of New York Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same
US11207285B2 (en) 2016-06-02 2021-12-28 Syndromex Ltd. Diabetes treatment regimens using alpha, alpha-substituted long-chain amphipathic carboxylates
US10729670B2 (en) * 2016-09-07 2020-08-04 Temple University—Of The Commonwealth Systems Of Higher Education Compositions and methods for treatment of insulin resistance
EP3761984A4 (en) 2018-03-07 2021-12-22 Temple University - Of The Commonwealth System of Higher Education COMPOSITIONS AND METHODS OF TREATMENT FOR INSULIN RESISTANCE
WO2019173633A1 (en) 2018-03-07 2019-09-12 Temple University - Of The Commonwealth System Of Higher Education Compositions and methods for treatment of insulin resistance
AU2019345297A1 (en) 2018-09-18 2021-04-29 1 Globe Biomedical Co., Ltd. Treatment for non-alcoholic fatty liver disease

Also Published As

Publication number Publication date
US11596615B2 (en) 2023-03-07
ZA201902155B (en) 2023-12-20
US10729670B2 (en) 2020-08-04
AU2017324510B2 (en) 2023-08-31
US20190192462A1 (en) 2019-06-27
CA3035972A1 (en) 2018-03-15
AU2017324510A1 (en) 2019-04-11
JP7235312B2 (ja) 2023-03-08
EP3509575A1 (en) 2019-07-17
MX2019002607A (es) 2019-09-18
CN110139644B (zh) 2023-05-23
EP3509575A4 (en) 2020-04-22
AU2023274183A1 (en) 2023-12-21
BR112019004405A2 (pt) 2020-06-23
JP2019526600A (ja) 2019-09-19
WO2018049019A1 (en) 2018-03-15
CN110139644A (zh) 2019-08-16
US20210046030A1 (en) 2021-02-18

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