MX2022005644A - Vectores vegetales, composiciones y usos relacionados con los mismos. - Google Patents

Vectores vegetales, composiciones y usos relacionados con los mismos.

Info

Publication number
MX2022005644A
MX2022005644A MX2022005644A MX2022005644A MX2022005644A MX 2022005644 A MX2022005644 A MX 2022005644A MX 2022005644 A MX2022005644 A MX 2022005644A MX 2022005644 A MX2022005644 A MX 2022005644A MX 2022005644 A MX2022005644 A MX 2022005644A
Authority
MX
Mexico
Prior art keywords
compositions
protein
uses relating
plant vectors
host plant
Prior art date
Application number
MX2022005644A
Other languages
English (en)
Inventor
Anne Elizabeth Simon
Georgios Vidalakis
Sohrab Bodaghi
Jingyuan Liu
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/060945 external-priority patent/WO2020102210A1/en
Application filed by Univ Maryland filed Critical Univ Maryland
Publication of MX2022005644A publication Critical patent/MX2022005644A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8281—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for bacterial resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/26011—Flexiviridae
    • C12N2770/26041—Use of virus, viral particle or viral elements as a vector
    • C12N2770/26043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un vector de ARN monocatenario adecuado para introducir un agente terapéutico, tal como un péptido, una proteína o un ARN pequeño, en una planta anfitriona. El vector no codifica para ninguna proteína de movimiento o proteína de cubierta, pero es capaz de replicación y movimiento sistémico y limitado por el floema dentro de la planta anfitriona.
MX2022005644A 2019-11-12 2020-11-12 Vectores vegetales, composiciones y usos relacionados con los mismos. MX2022005644A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2019/060945 WO2020102210A1 (en) 2018-11-13 2019-11-12 Plant vectors, compositions and uses relating thereto
US202063023712P 2020-05-12 2020-05-12
PCT/US2020/060228 WO2021097086A1 (en) 2019-11-12 2020-11-12 Plant vectors, compositions and uses relating thereto

Publications (1)

Publication Number Publication Date
MX2022005644A true MX2022005644A (es) 2022-12-13

Family

ID=75912827

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022005644A MX2022005644A (es) 2019-11-12 2020-11-12 Vectores vegetales, composiciones y usos relacionados con los mismos.

Country Status (7)

Country Link
US (2) US20240279675A1 (es)
EP (1) EP4058568A4 (es)
CN (1) CN115052979A (es)
AU (1) AU2020381450A1 (es)
BR (1) BR112022009127A2 (es)
MX (1) MX2022005644A (es)
WO (1) WO2021097086A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210101227A (ko) * 2018-11-13 2021-08-18 유니버시티 오브 매릴랜드, 칼리지 파크 식물 벡터, 조성물 및 그것들과 관련된 용도
AU2022203005A1 (en) * 2021-05-21 2022-12-08 Silvec Biologics Inc. Plant vectors, compositions and uses relating thereto
CN117802164A (zh) * 2023-12-29 2024-04-02 华中农业大学 基于植物内原核生物基因沉默***的黄龙病防治方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0253491A (ja) * 1988-08-17 1990-02-22 Japan Tobacco Inc ベクター及びその利用方法
US7045685B2 (en) * 1992-08-14 2006-05-16 Commonwealth Scientific And Industrial Research Organisation Insect viruses and their uses in protecting plants
WO2000005379A1 (en) * 1998-07-24 2000-02-03 Scottish Crop Research Institute Polynucleotide transporter protein
EP1686176A1 (en) * 2005-01-28 2006-08-02 Icon Genetics AG Production of antibodies in plants with plus-sense single-stranded viral RNA vectors
US20110288147A1 (en) * 2008-09-22 2011-11-24 Bob Dale Brown Compositions and methods for the specific inhibition of gene expression by DSRNA containing a tetraloop
US10017747B2 (en) * 2011-09-21 2018-07-10 University Of Florida Research Foundation, Inc. Citrus tristeza virus based vectors for foreign gene/s expression
CN105358695B (zh) * 2013-01-01 2019-07-12 A.B.种子有限公司 将dsRNA引入植物种子以调节基因表达的方法
CN108064133A (zh) * 2014-05-04 2018-05-22 佛利斯特创新有限公司 用于蚊虫控制的组合物和所述组合物的用途
US11208638B2 (en) * 2015-01-12 2021-12-28 The Regents Of The University Of California Heterodimeric Cas9 and methods of use thereof
CN105567728B (zh) * 2016-01-18 2019-01-29 中国农业科学院郑州果树研究所 一种携带gfp基因的甜瓜坏死斑点病毒侵染性克隆载体
CA3071440C (en) * 2017-07-31 2023-09-26 R. J. Reynolds Tobacco Company Methods and compositions for viral-based gene editing in plants
JP2021534817A (ja) * 2018-08-17 2021-12-16 サントル ナショナル ドゥ ラ ルシェルシュ シアンティフィック 動物を病原性細菌から保護するならびに／または相利共生および片利共生細菌の有益な効果を促進するためのｒｎａベースの治療方法
KR20210101227A (ko) * 2018-11-13 2021-08-18 유니버시티 오브 매릴랜드, 칼리지 파크 식물 벡터, 조성물 및 그것들과 관련된 용도

Also Published As

Publication number Publication date
BR112022009127A2 (pt) 2022-08-16
EP4058568A4 (en) 2024-04-03
US20210355499A1 (en) 2021-11-18
US20240279675A1 (en) 2024-08-22
WO2021097086A1 (en) 2021-05-20
AU2020381450A1 (en) 2022-06-02
EP4058568A1 (en) 2022-09-21
CN115052979A (zh) 2022-09-13

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