MX2022000889A - Composiciones solidas que comprenden un derivado de egf(a) y una sal de acido n-(8-(2-hidroxibenzoil)amino)caprilico. - Google Patents
Composiciones solidas que comprenden un derivado de egf(a) y una sal de acido n-(8-(2-hidroxibenzoil)amino)caprilico.Info
- Publication number
- MX2022000889A MX2022000889A MX2022000889A MX2022000889A MX2022000889A MX 2022000889 A MX2022000889 A MX 2022000889A MX 2022000889 A MX2022000889 A MX 2022000889A MX 2022000889 A MX2022000889 A MX 2022000889A MX 2022000889 A MX2022000889 A MX 2022000889A
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxybenzoyl
- egf
- amino
- salt
- caprylic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se refiere a composiciones farmacéuticas que comprenden un inhibidor de PCSK9, tal como un péptido de EGF(A), y una sal de ácido N-(8-(2-hidroxibenzoil)amino)caprílico. La invención se refiere además a procesos para la preparación de las composiciones, y a su uso en medicina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19190506 | 2019-08-07 | ||
PCT/EP2020/072227 WO2021023855A1 (en) | 2019-08-07 | 2020-08-07 | Solid compositions comprising an egf(a) derivative and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022000889A true MX2022000889A (es) | 2022-02-14 |
Family
ID=67551283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022000889A MX2022000889A (es) | 2019-08-07 | 2020-08-07 | Composiciones solidas que comprenden un derivado de egf(a) y una sal de acido n-(8-(2-hidroxibenzoil)amino)caprilico. |
Country Status (14)
Country | Link |
---|---|
US (1) | US20220323544A1 (es) |
EP (1) | EP4009958A1 (es) |
KR (1) | KR20220046565A (es) |
CN (1) | CN114222581A (es) |
AR (1) | AR122299A1 (es) |
AU (1) | AU2020326265A1 (es) |
BR (1) | BR112022000529A2 (es) |
CA (1) | CA3144618A1 (es) |
CO (1) | CO2022000575A2 (es) |
IL (1) | IL289505A (es) |
MX (1) | MX2022000889A (es) |
PE (1) | PE20220486A1 (es) |
TW (1) | TW202120118A (es) |
WO (1) | WO2021023855A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20240036563A (ko) * | 2021-07-15 | 2024-03-20 | 노보 노르디스크 에이/에스 | N-(8-(2-하이드록시벤조일)아미노)카프릴산의 염을 포함하는 정제 |
WO2023012263A1 (en) | 2021-08-04 | 2023-02-09 | Novo Nordisk A/S | Solid oral peptide formulations |
WO2024110614A1 (en) | 2022-11-25 | 2024-05-30 | Novo Nordisk A/S | Oral administration of peptide therapeutics, such as glp-1 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
EP1149066B1 (en) | 1999-02-05 | 2005-11-09 | Emisphere Technologies, Inc. | Method of preparing alkylated salicylamides |
US7262325B2 (en) | 2000-06-02 | 2007-08-28 | Emisphere Technologies, Inc. | Method of preparing salicylamides |
US8927015B2 (en) | 2006-04-12 | 2015-01-06 | Emisphere Technologies, Inc. | Formulations for delivering insulin |
CN101506147B (zh) | 2006-09-07 | 2012-03-21 | 霍夫曼-拉罗奇有限公司 | 用于制备snac(n-(8-[2-羟基苯甲酰基]-氨基)辛酸钠)的方法 |
DK3326620T3 (da) | 2010-12-16 | 2020-05-25 | Novo Nordisk As | Faste sammensætninger omfattende en glp-1-agonist og et salt af n-(8-(2- hydroxybenzoyl)amino)caprylsyre |
CN103717615A (zh) | 2011-06-20 | 2014-04-09 | 霍夫曼-拉罗奇有限公司 | 结合pcsk9的多肽及使用方法 |
HUE062740T2 (hu) | 2012-03-22 | 2023-12-28 | Novo Nordisk As | GLP-1 peptidek készítményei és elõállításuk |
US10335369B2 (en) * | 2012-03-22 | 2019-07-02 | Novo Nordisk A/S | Compositions comprising a delivery agent and preparation thereof |
MX2018008681A (es) | 2016-01-13 | 2018-09-17 | Novo Nordisk As | Analogos del dominio a similar al factor de crecimiento epidermico (egf(a)) con sustituyentes de acidos grasos. |
MX2018016057A (es) * | 2016-06-24 | 2019-05-06 | Hoffmann La Roche | Composiciones y metodos para tratar enfermedades cardiovasculares. |
US20200165313A1 (en) | 2017-07-19 | 2020-05-28 | Novo Nordisk A/S | Egf(a) analogues, preparation, formulations and uses thereof |
-
2020
- 2020-08-07 MX MX2022000889A patent/MX2022000889A/es unknown
- 2020-08-07 AU AU2020326265A patent/AU2020326265A1/en not_active Withdrawn
- 2020-08-07 PE PE2022000111A patent/PE20220486A1/es unknown
- 2020-08-07 BR BR112022000529A patent/BR112022000529A2/pt not_active Application Discontinuation
- 2020-08-07 TW TW109126752A patent/TW202120118A/zh unknown
- 2020-08-07 CN CN202080055600.1A patent/CN114222581A/zh not_active Withdrawn
- 2020-08-07 US US17/628,697 patent/US20220323544A1/en not_active Abandoned
- 2020-08-07 WO PCT/EP2020/072227 patent/WO2021023855A1/en unknown
- 2020-08-07 EP EP20750288.1A patent/EP4009958A1/en not_active Withdrawn
- 2020-08-07 KR KR1020227004059A patent/KR20220046565A/ko unknown
- 2020-08-07 AR ARP200102265A patent/AR122299A1/es unknown
- 2020-08-07 CA CA3144618A patent/CA3144618A1/en not_active Withdrawn
-
2021
- 2021-12-29 IL IL289505A patent/IL289505A/en unknown
-
2022
- 2022-01-24 CO CONC2022/0000575A patent/CO2022000575A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2020326265A1 (en) | 2022-02-03 |
KR20220046565A (ko) | 2022-04-14 |
IL289505A (en) | 2022-02-01 |
CN114222581A (zh) | 2022-03-22 |
CO2022000575A2 (es) | 2022-04-29 |
EP4009958A1 (en) | 2022-06-15 |
TW202120118A (zh) | 2021-06-01 |
CA3144618A1 (en) | 2021-02-11 |
WO2021023855A1 (en) | 2021-02-11 |
US20220323544A1 (en) | 2022-10-13 |
AR122299A1 (es) | 2022-08-31 |
BR112022000529A2 (pt) | 2022-03-03 |
PE20220486A1 (es) | 2022-04-04 |
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