MX2021010021A - Proteínas sintéticas autoensamblables. - Google Patents
Proteínas sintéticas autoensamblables.Info
- Publication number
- MX2021010021A MX2021010021A MX2021010021A MX2021010021A MX2021010021A MX 2021010021 A MX2021010021 A MX 2021010021A MX 2021010021 A MX2021010021 A MX 2021010021A MX 2021010021 A MX2021010021 A MX 2021010021A MX 2021010021 A MX2021010021 A MX 2021010021A
- Authority
- MX
- Mexico
- Prior art keywords
- self
- present disclosure
- immunogenic
- limited
- antigens
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 230000008105 immune reaction Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente divulgación prové una proteína inmunogénica sintética para uso como un agente inmunomodulador para mejorar las reacciones inmunes de mamíferos hacia proteína conjugada o péptido que contiene antígenos que son de otra manera poco inmunogénicos, incluyendo, pero no limitado a auto-antígenos. Las proteínas inmunogénicas quiméricas de la presente divulgación se pueden utilizar en el tratamiento de muchas enfermedades, incluyendo, pero no limitado a, cánceres, enfermedades infecciosas, enfermedades autoinmunes, alergias y cualquier indicación clínica que se ve implicada o afectada por la inmunorespuesta de un hospedero mamífero.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361791268P | 2013-03-15 | 2013-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021010021A true MX2021010021A (es) | 2021-12-10 |
Family
ID=51225849
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015012461A MX2015012461A (es) | 2013-03-15 | 2014-03-17 | Proteinas sintéticas autoensamblables. |
MX2021010021A MX2021010021A (es) | 2013-03-15 | 2015-09-11 | Proteínas sintéticas autoensamblables. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015012461A MX2015012461A (es) | 2013-03-15 | 2014-03-17 | Proteinas sintéticas autoensamblables. |
Country Status (14)
Country | Link |
---|---|
US (3) | US10736948B2 (es) |
EP (1) | EP2970409A2 (es) |
JP (1) | JP6873530B2 (es) |
KR (2) | KR102427429B1 (es) |
CN (2) | CN111978409B (es) |
AU (1) | AU2014229561B2 (es) |
BR (1) | BR112015023402A2 (es) |
CA (1) | CA2904506A1 (es) |
HK (1) | HK1214606A1 (es) |
IL (3) | IL286537B (es) |
MX (2) | MX2015012461A (es) |
MY (1) | MY187936A (es) |
RU (1) | RU2747857C2 (es) |
WO (1) | WO2014140894A2 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160333087A1 (en) | 2015-05-12 | 2016-11-17 | Bioven 3 Limited | Methods and compositions for inhibition of egf/egfr pathway in combination with tyrosine kinase inhibitors |
WO2019016597A2 (en) * | 2017-07-18 | 2019-01-24 | Bioven 3 Limited | SYNTHETIC PROTEINS AND THEIR THERAPEUTIC USES |
EP3990010A1 (en) * | 2019-06-25 | 2022-05-04 | In3Bio Ltd. | Stabilized chimeric synthetic proteins and therapeutic uses thereof |
MX2022005306A (es) | 2019-11-07 | 2022-08-08 | In3Bio Ltd | Metodos y composiciones para uso de anticuerpos del factor de crecimiento en combinacion con inhibidores de cinasa dirigidos a no tirosinas. |
CN114019166B (zh) * | 2021-09-27 | 2024-02-27 | 浙江省食品药品检验研究院 | 一种检测龙葵素的试纸条及其应用 |
Family Cites Families (37)
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US3238190A (en) | 1963-10-23 | 1966-03-01 | Madaus & Co K G Fa Dr | Aescin recovery |
SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
US6153203A (en) | 1993-10-08 | 2000-11-28 | Duotol Ab | Immunological tolerance-inducing agent |
EP0657175B1 (en) * | 1993-12-09 | 2005-03-02 | Centro de Inmunologia Molecular | Vaccine comprising human autologous epidermal growth factor and use thereof |
CA2261433A1 (en) * | 1993-12-09 | 1995-06-10 | Belinda Sanchez Ramirez | Composition comprising autologous epidermal growth factor |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
EP0958364A4 (en) * | 1996-10-23 | 2001-10-31 | Univ Pennsylvania | IMMUNOTHERAPY AND IMPROVED Vaccines |
CA2302522C (en) | 1997-08-29 | 2010-08-17 | Aquila Biopharmaceuticals, Inc. | Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient |
US20080249019A1 (en) * | 1998-08-25 | 2008-10-09 | Syntaxin, Ltd. | Treatment of mucus hypersecretion |
CA2370697C (en) | 1999-04-19 | 2012-03-06 | Smithkline Beecham Biologicals S.A. | Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide |
SK782002A3 (en) * | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
EP1222202A2 (en) | 1999-10-08 | 2002-07-17 | Active Biotech AB | Ab5 toxin b subunit mutants with altered chemical conjug ation characteristics |
PE20020572A1 (es) * | 2000-12-06 | 2002-07-31 | Centro Inmunologia Molecular | Preparaciones para potenciar la inmunogenicidad de antigenos poco inmunogenicos |
EP1452556B1 (en) | 2001-06-21 | 2009-06-10 | Teijin Limited | Near infrared ray shielding film |
GB0115382D0 (en) | 2001-06-22 | 2001-08-15 | Univ Bristol | Mutant |
JP2005512538A (ja) * | 2001-12-14 | 2005-05-12 | セントカー・インコーポレーテツド | 無血清培地中でタンパク質を製造するのに有用なクローン性骨髄腫細胞系 |
DK1485475T3 (da) * | 2002-03-15 | 2008-01-21 | Cellectis | Hybrid meganuklease og enkeltkædet maganuklease og brug deraf |
DE602004031341D1 (de) * | 2003-07-21 | 2011-03-24 | Transgene Sa | Multifunktionelle cytokine |
JP4623625B2 (ja) * | 2003-07-24 | 2011-02-02 | 株式会社AMBiS | ヘテロ型5量体組換えワクチン |
US7320795B2 (en) * | 2003-07-30 | 2008-01-22 | Vaccine Research Institute Of San Diego | Rodent hepatitis B virus core proteins as vaccine platforms and methods of use thereof |
AU2004296181A1 (en) * | 2003-12-05 | 2005-06-23 | Northwestern University | Self-assembling peptide amphiphiles and related methods for growth factor delivery |
NZ549048A (en) | 2004-02-11 | 2009-04-30 | Angeletti P Ist Richerche Bio | Carcinoembryonic antigen fusion proteins and uses thereof |
EP1921149A1 (en) * | 2006-11-13 | 2008-05-14 | AEterna Zentaris GmbH | Microorganisms as carriers of nucleotide sequences coding for antigens and protein toxins, process of manufacturing and uses thereof |
CN101970498A (zh) | 2007-10-25 | 2011-02-09 | 维文蒂阿生物技术公司 | 针对变体HnRNPG的癌相关表位的抗体及其应用 |
CN103768580A (zh) | 2007-12-19 | 2014-05-07 | 托勒兰泽亚股份公司 | 治疗自身免疫和过敏性疾病的组合物及方法 |
RU2509570C2 (ru) | 2008-06-09 | 2014-03-20 | Бхарат Байотек Интернэшнл Лимитед | Вакцинная композиция, пригодная при инфекциях hpv и вирусом гепатита в, и способ ее получения |
JP2010050586A (ja) | 2008-08-20 | 2010-03-04 | Nec Corp | 通信装置及びそれに用いる装置コンポーネント複合冗長化方法 |
JPWO2010050586A1 (ja) * | 2008-10-31 | 2012-03-29 | ディナベック株式会社 | 組み換え蛋白質の発現を増強する方法 |
EP2786762B1 (en) * | 2008-12-19 | 2019-01-30 | MacroGenics, Inc. | Covalent diabodies and uses thereof |
JP2011097930A (ja) * | 2009-10-07 | 2011-05-19 | Hokkaido Univ | 光活性化生理機能センサータンパク質 |
RU2480524C2 (ru) * | 2010-09-13 | 2013-04-27 | Учреждение Российской академии наук Институт биоорганической химии им. академии М.М. Шемякина и Ю.А. Овчинникова РАН | Конструкция на основе белковой пары барназа-барстар и способ ее получения |
US9499605B2 (en) * | 2011-03-03 | 2016-11-22 | Zymeworks Inc. | Multivalent heteromultimer scaffold design and constructs |
CN102604993B (zh) | 2012-01-10 | 2013-03-20 | 天津耀宇生物技术有限公司 | 免疫佐剂与幽门螺杆菌抗原融合蛋白口服疫苗及其制备方法 |
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2014
- 2014-03-17 KR KR1020207037800A patent/KR102427429B1/ko active IP Right Grant
- 2014-03-17 WO PCT/IB2014/001125 patent/WO2014140894A2/en active Application Filing
- 2014-03-17 EP EP14744148.9A patent/EP2970409A2/en active Pending
- 2014-03-17 CN CN202010734323.9A patent/CN111978409B/zh active Active
- 2014-03-17 BR BR112015023402A patent/BR112015023402A2/pt not_active Application Discontinuation
- 2014-03-17 AU AU2014229561A patent/AU2014229561B2/en active Active
- 2014-03-17 KR KR1020157026975A patent/KR102391734B1/ko active IP Right Grant
- 2014-03-17 JP JP2015562395A patent/JP6873530B2/ja active Active
- 2014-03-17 CN CN201480026671.3A patent/CN105209481B/zh active Active
- 2014-03-17 RU RU2015143217A patent/RU2747857C2/ru not_active Application Discontinuation
- 2014-03-17 MY MYPI2015703117A patent/MY187936A/en unknown
- 2014-03-17 CA CA2904506A patent/CA2904506A1/en active Pending
- 2014-03-17 IL IL286537A patent/IL286537B/en unknown
- 2014-03-17 MX MX2015012461A patent/MX2015012461A/es unknown
-
2015
- 2015-09-03 IL IL241116A patent/IL241116B/en active IP Right Grant
- 2015-09-11 MX MX2021010021A patent/MX2021010021A/es unknown
- 2015-09-15 US US14/854,224 patent/US10736948B2/en active Active
-
2016
- 2016-03-04 HK HK16102480.5A patent/HK1214606A1/zh unknown
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2020
- 2020-03-04 IL IL273051A patent/IL273051B/en unknown
- 2020-04-08 US US16/843,118 patent/US11419923B2/en active Active
-
2022
- 2022-07-12 US US17/862,952 patent/US20230042534A1/en active Pending
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