MX2021009854A - Compuesto derivado heterociclico novedoso y uso del mismo. - Google Patents
Compuesto derivado heterociclico novedoso y uso del mismo.Info
- Publication number
- MX2021009854A MX2021009854A MX2021009854A MX2021009854A MX2021009854A MX 2021009854 A MX2021009854 A MX 2021009854A MX 2021009854 A MX2021009854 A MX 2021009854A MX 2021009854 A MX2021009854 A MX 2021009854A MX 2021009854 A MX2021009854 A MX 2021009854A
- Authority
- MX
- Mexico
- Prior art keywords
- derivative compound
- same
- novel
- heterotricyclic
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente descripción se relaciona con compuestos derivados heterotricíclicos novedosos y con el uso de los mismos, y más particularmente, con compuestos derivados heterotricíclicos novedosos que tienen actividad inhibitoria contra la actividad del EZH1 (potenciador de zeste homólogo 1) y/o EZH2 (potenciador de zeste homólogo 2), sales farmacéuticamente aceptables de los mismos, o composiciones farmacéuticas que contienen estos compuestos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020190019544A KR102689665B1 (ko) | 2019-02-19 | 신규한 헤테로트리시클릭 유도체 화합물 및 이의 용도 | |
PCT/KR2020/002427 WO2020171606A1 (ko) | 2019-02-19 | 2020-02-19 | 신규한 헤테로트리시클릭 유도체 화합물 및 이의 용도 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021009854A true MX2021009854A (es) | 2021-09-28 |
Family
ID=72144293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021009854A MX2021009854A (es) | 2019-02-19 | 2020-02-19 | Compuesto derivado heterociclico novedoso y uso del mismo. |
Country Status (16)
Country | Link |
---|---|
US (1) | US20220135582A1 (es) |
EP (1) | EP3929199A4 (es) |
JP (1) | JP7358491B2 (es) |
CN (1) | CN113423710B (es) |
AU (1) | AU2020226042B2 (es) |
BR (1) | BR112021016448A2 (es) |
CA (1) | CA3130456C (es) |
CL (1) | CL2021002165A1 (es) |
EA (1) | EA202191991A1 (es) |
IL (1) | IL285604A (es) |
MX (1) | MX2021009854A (es) |
PE (1) | PE20211703A1 (es) |
SG (1) | SG11202108940RA (es) |
TW (1) | TWI829869B (es) |
WO (1) | WO2020171606A1 (es) |
ZA (1) | ZA202105970B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3797108B1 (en) | 2018-05-21 | 2022-07-20 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
JP7387907B2 (ja) * | 2020-08-13 | 2023-11-28 | ハンミ ファーマシューティカル カンパニー リミテッド | 新規なジオキソロイソキノリノン誘導体化合物及びその用途{novel dioxoloisoquinolinone derivatives and use thereof} |
WO2022179584A1 (zh) * | 2021-02-26 | 2022-09-01 | 南京药石科技股份有限公司 | 新型ezh2抑制剂及其用途 |
WO2023217018A1 (zh) * | 2022-05-07 | 2023-11-16 | 贝达药业股份有限公司 | Ezh2抑制剂及其在医药上的应用 |
TW202400602A (zh) * | 2022-05-31 | 2024-01-01 | 大陸商和記黃埔醫藥(上海)有限公司 | 三環類化合物及其用途 |
WO2023244918A1 (en) | 2022-06-13 | 2023-12-21 | Treeline Biosciences, Inc. | Quinolone bcl6 bifunctional degraders |
WO2023244917A1 (en) | 2022-06-13 | 2023-12-21 | Treeline Biosciences, Inc. | 1,8-naphthyridin-2-one heterobifunctional bcl6 degraders |
WO2024038115A1 (en) | 2022-08-17 | 2024-02-22 | Morphosys Ag | Therapy comprising anti-cd19 antibody and ezh2 modulators |
CN115974856B (zh) * | 2022-12-28 | 2023-08-11 | 北京康立生医药技术开发有限公司 | 一种治疗成人t细胞白血病淋巴瘤药物伐美妥司他的制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
WO2013067302A1 (en) * | 2011-11-04 | 2013-05-10 | Glaxosmithkline Intellectual Property (No. 2) Limited | Method of treatment |
UA111305C2 (uk) * | 2012-12-21 | 2016-04-11 | Пфайзер Інк. | Конденсовані лактами арилу та гетероарилу |
WO2015077194A1 (en) * | 2013-11-22 | 2015-05-28 | Bristol-Myers Squibb Company | Inhibitors of lysine methyl transferase |
PT3121175T (pt) * | 2014-03-17 | 2020-03-05 | Daiichi Sankyo Co Ltd | Derivados de 1,3-benzodioxol como inibidores de ezh1 e/ou ezh2 |
WO2015193768A1 (en) | 2014-06-17 | 2015-12-23 | Pfizer Inc. | Aryl fused lactams as ezh2 modulators |
WO2015193765A1 (en) * | 2014-06-17 | 2015-12-23 | Pfizer Inc. | Substituted dihydroisoquinolinone compounds |
US10308638B2 (en) | 2015-03-25 | 2019-06-04 | The Regents Of The University Of California | Selective alpha-7 nicotinic receptor agonists and methods for making and using them |
EP3797108B1 (en) * | 2018-05-21 | 2022-07-20 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
JP7387907B2 (ja) * | 2020-08-13 | 2023-11-28 | ハンミ ファーマシューティカル カンパニー リミテッド | 新規なジオキソロイソキノリノン誘導体化合物及びその用途{novel dioxoloisoquinolinone derivatives and use thereof} |
-
2020
- 2020-02-19 JP JP2021548205A patent/JP7358491B2/ja active Active
- 2020-02-19 CN CN202080013624.0A patent/CN113423710B/zh active Active
- 2020-02-19 BR BR112021016448A patent/BR112021016448A2/pt unknown
- 2020-02-19 EP EP20759257.7A patent/EP3929199A4/en active Pending
- 2020-02-19 WO PCT/KR2020/002427 patent/WO2020171606A1/ko unknown
- 2020-02-19 PE PE2021001370A patent/PE20211703A1/es unknown
- 2020-02-19 SG SG11202108940RA patent/SG11202108940RA/en unknown
- 2020-02-19 EA EA202191991A patent/EA202191991A1/ru unknown
- 2020-02-19 AU AU2020226042A patent/AU2020226042B2/en active Active
- 2020-02-19 US US17/431,933 patent/US20220135582A1/en active Pending
- 2020-02-19 TW TW109105374A patent/TWI829869B/zh active
- 2020-02-19 CA CA3130456A patent/CA3130456C/en active Active
- 2020-02-19 MX MX2021009854A patent/MX2021009854A/es unknown
-
2021
- 2021-08-14 IL IL285604A patent/IL285604A/en unknown
- 2021-08-16 CL CL2021002165A patent/CL2021002165A1/es unknown
- 2021-08-19 ZA ZA2021/05970A patent/ZA202105970B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3929199A4 (en) | 2022-10-26 |
SG11202108940RA (en) | 2021-09-29 |
CL2021002165A1 (es) | 2022-04-22 |
AU2020226042B2 (en) | 2022-07-14 |
CN113423710A (zh) | 2021-09-21 |
EA202191991A1 (ru) | 2021-12-10 |
JP7358491B2 (ja) | 2023-10-10 |
AU2020226042A1 (en) | 2021-09-09 |
KR20200101219A (ko) | 2020-08-27 |
IL285604A (en) | 2021-09-30 |
EP3929199A1 (en) | 2021-12-29 |
TWI829869B (zh) | 2024-01-21 |
WO2020171606A1 (ko) | 2020-08-27 |
CN113423710B (zh) | 2024-06-14 |
JP2022522648A (ja) | 2022-04-20 |
BR112021016448A2 (pt) | 2021-11-09 |
PE20211703A1 (es) | 2021-09-01 |
CA3130456C (en) | 2023-10-03 |
ZA202105970B (en) | 2023-05-31 |
CA3130456A1 (en) | 2020-08-27 |
TW202045512A (zh) | 2020-12-16 |
US20220135582A1 (en) | 2022-05-05 |
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