MX2021008867A - Composiciones reactantes marcadas de intensidad alta y metodos de secuenciamiento. - Google Patents
Composiciones reactantes marcadas de intensidad alta y metodos de secuenciamiento.Info
- Publication number
- MX2021008867A MX2021008867A MX2021008867A MX2021008867A MX2021008867A MX 2021008867 A MX2021008867 A MX 2021008867A MX 2021008867 A MX2021008867 A MX 2021008867A MX 2021008867 A MX2021008867 A MX 2021008867A MX 2021008867 A MX2021008867 A MX 2021008867A
- Authority
- MX
- Mexico
- Prior art keywords
- sequencing
- methods
- high intensity
- labeled reactant
- reactant compositions
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/301—Hairpin oligonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/103—Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Composiciones útiles para la detección de moléculas individuales en una muestra se proveen; en algunos aspectos, la divulgación proporciona un nucleótido conectado a un ácido nucleico que comprende un marcador FRET que comprende al menos tres moléculas luminiscentes; en las modalidades, los ácidos nucleicos descritos en la presente comprenden una o más características que proveen intensidad de fluorescencia mejorada; en algunos aspectos, se proveen métodos de secuenciamiento usando los nucleótidos marcados de la descripción.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962795932P | 2019-01-23 | 2019-01-23 | |
PCT/US2020/014856 WO2020154546A1 (en) | 2019-01-23 | 2020-01-23 | High intensity labeled reactant compositions and methods for sequencing |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021008867A true MX2021008867A (es) | 2021-08-19 |
Family
ID=69743907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021008867A MX2021008867A (es) | 2019-01-23 | 2020-01-23 | Composiciones reactantes marcadas de intensidad alta y metodos de secuenciamiento. |
Country Status (10)
Country | Link |
---|---|
US (2) | US11613772B2 (es) |
EP (1) | EP3914603A1 (es) |
JP (1) | JP2022518056A (es) |
KR (1) | KR20210118862A (es) |
CN (1) | CN113614097A (es) |
AU (1) | AU2020210940A1 (es) |
BR (1) | BR112021013787A2 (es) |
CA (1) | CA3127102A1 (es) |
MX (1) | MX2021008867A (es) |
WO (1) | WO2020154546A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102626317B1 (ko) | 2017-07-24 | 2024-01-18 | 퀀텀-에스아이 인코포레이티드 | 고강도 표지된 반응물 조성물 및 서열분석 방법 |
WO2022159193A1 (en) * | 2021-01-20 | 2022-07-28 | The Regents Of The University Of California | Proximity-dependent photoactivation |
JPWO2023032995A1 (es) * | 2021-08-31 | 2023-03-09 | ||
US20230221330A1 (en) * | 2022-01-12 | 2023-07-13 | Quantum-Si Incorporated | Labeled binding reagents and methods of use thereof |
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US10836798B2 (en) | 2018-11-08 | 2020-11-17 | Government Of The United States Of America, As Represented By The Secretary Of Commerce | Amino acid-specific binder and selectively identifying an amino acid |
-
2020
- 2020-01-23 WO PCT/US2020/014856 patent/WO2020154546A1/en unknown
- 2020-01-23 US US16/751,138 patent/US11613772B2/en active Active
- 2020-01-23 CA CA3127102A patent/CA3127102A1/en active Pending
- 2020-01-23 KR KR1020217026131A patent/KR20210118862A/ko unknown
- 2020-01-23 MX MX2021008867A patent/MX2021008867A/es unknown
- 2020-01-23 JP JP2021542532A patent/JP2022518056A/ja active Pending
- 2020-01-23 CN CN202080023453.XA patent/CN113614097A/zh active Pending
- 2020-01-23 BR BR112021013787-4A patent/BR112021013787A2/pt not_active Application Discontinuation
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2023
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CN113614097A (zh) | 2021-11-05 |
AU2020210940A1 (en) | 2021-07-29 |
CA3127102A1 (en) | 2020-07-30 |
WO2020154546A1 (en) | 2020-07-30 |
JP2022518056A (ja) | 2022-03-11 |
US11613772B2 (en) | 2023-03-28 |
BR112021013787A2 (pt) | 2021-10-05 |
US20200232017A1 (en) | 2020-07-23 |
KR20210118862A (ko) | 2021-10-01 |
US20240124918A1 (en) | 2024-04-18 |
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