MX2020005100A - Cultivo de placenta para aislar exosomas. - Google Patents
Cultivo de placenta para aislar exosomas.Info
- Publication number
- MX2020005100A MX2020005100A MX2020005100A MX2020005100A MX2020005100A MX 2020005100 A MX2020005100 A MX 2020005100A MX 2020005100 A MX2020005100 A MX 2020005100A MX 2020005100 A MX2020005100 A MX 2020005100A MX 2020005100 A MX2020005100 A MX 2020005100A
- Authority
- MX
- Mexico
- Prior art keywords
- placenta
- exosomes
- cultivation
- isolate
- isolate exosomes
- Prior art date
Links
- 210000001808 exosome Anatomy 0.000 title abstract 5
- 210000002826 placenta Anatomy 0.000 title abstract 4
- 238000013459 approach Methods 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
- C12N2502/025—Coculture with; Conditioned medium produced by embryonic cells extra-embryonic cells, e.g. amniotic epithelium, placental cells, Wharton's jelly
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
- C12N2509/10—Mechanical dissociation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Abstract
Se proporcionan varios enfoques para producir, aislar y caracterizar exosomas recuperados a partir de un cultivo de placenta o una parte de esta. Las alternativas que se describen en la presente facilitan la producción, aislamiento y caracterización de exosomas, los cuales se pueden usar como agentes terapéuticos y herramientas biotecnológicas. También se proporcionan en la presente poblaciones de exosomas derivados de cultivo de placenta o cultivo de partes de la placenta. Además, se proporcionan composiciones que comprenden las poblaciones de exosomas y métodos para usarlas en el tratamiento de sujetos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762587335P | 2017-11-16 | 2017-11-16 | |
PCT/US2018/061697 WO2019099955A1 (en) | 2017-11-16 | 2018-11-16 | Cultivation of placenta to isolate exosomes |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020005100A true MX2020005100A (es) | 2020-11-24 |
Family
ID=65279618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020005100A MX2020005100A (es) | 2017-11-16 | 2018-11-16 | Cultivo de placenta para aislar exosomas. |
Country Status (13)
Country | Link |
---|---|
US (2) | US20190307686A1 (es) |
EP (1) | EP3710575A1 (es) |
JP (2) | JP2021503301A (es) |
KR (1) | KR20200083596A (es) |
CN (1) | CN111433352A (es) |
AU (1) | AU2018370157A1 (es) |
CA (1) | CA3082880A1 (es) |
EA (1) | EA202091219A1 (es) |
MA (1) | MA51649A (es) |
MX (1) | MX2020005100A (es) |
PH (1) | PH12020550660A1 (es) |
SG (1) | SG11202004523SA (es) |
WO (1) | WO2019099955A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2021015528A (es) * | 2019-06-19 | 2022-02-03 | Celularity Inc | Exosomas para el tratamiento de enfermedades. |
EP4123019A4 (en) * | 2020-03-18 | 2024-04-17 | The Catholic University Of Korea Industry-Academic Cooperation Foundation | EXOSOME OR MIMETIC FROM UMBILICAL CORD BLOOD PLASMA AND PHARMACEUTICAL USE THEREOF |
EP4136456A1 (en) * | 2020-04-17 | 2023-02-22 | Therawis Diagnostics GmbH | Method for enriching exosomes |
AU2021261384A1 (en) * | 2020-04-22 | 2022-12-22 | Direct Biologics Llc | Methods and compositions for treating inflammatory conditions associated with infectious disease |
KR102317052B1 (ko) * | 2020-05-04 | 2021-10-25 | 주식회사 티에스셀바이오 | 태반 유래의 세포외 소포의 항염증 항바이러스 효과 조성물 |
TW202146034A (zh) * | 2020-05-05 | 2021-12-16 | 美國商加速生物科學有限公司 | 包含有分泌蛋白體的藥學與化妝品組成物 |
KR102316777B1 (ko) * | 2020-06-26 | 2021-10-25 | 주식회사 씨케이엑소젠 | 엑소좀 생산 조절 세포, 이를 포함하는 조성물, 이로부터 얻은 엑소좀 및 엑소좀 생산 방법 |
CN112903999A (zh) * | 2021-01-20 | 2021-06-04 | 蚌埠医学院第一附属医院(蚌埠医学院附属肿瘤医院) | 一种用于纳米流式细胞仪检测的外泌体的制备方法及应用 |
JP7044429B1 (ja) * | 2021-12-20 | 2022-03-30 | 株式会社 バイオミメティクスシンパシーズ | 腫瘍を縮小、又は消失させるための組成物 |
CN117987350B (zh) * | 2024-04-03 | 2024-06-21 | 优智嘉(天津)生物科技有限公司 | 一种人胎盘绒毛外泌体快速提取试剂盒、提取方法、胎盘外泌体及应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2687219A1 (en) * | 2012-07-18 | 2014-01-22 | Universität Duisburg-Essen | Use of preparations comprising exosomes derived from mesenchymal stem cells (MSCs) in the prevention and therapy of inflammatory conditions |
AU2015330855A1 (en) * | 2014-10-09 | 2017-04-27 | Celularity Inc. | Placenta-derived adherent cell exosomes and uses thereof |
CN106282107A (zh) * | 2016-08-30 | 2017-01-04 | 章毅 | 人胎盘间充质干细胞源分离外泌体的方法及其应用 |
-
2018
- 2018-11-16 CA CA3082880A patent/CA3082880A1/en active Pending
- 2018-11-16 MA MA051649A patent/MA51649A/fr unknown
- 2018-11-16 WO PCT/US2018/061697 patent/WO2019099955A1/en unknown
- 2018-11-16 MX MX2020005100A patent/MX2020005100A/es unknown
- 2018-11-16 AU AU2018370157A patent/AU2018370157A1/en active Pending
- 2018-11-16 SG SG11202004523SA patent/SG11202004523SA/en unknown
- 2018-11-16 KR KR1020207016887A patent/KR20200083596A/ko active Search and Examination
- 2018-11-16 CN CN201880079103.8A patent/CN111433352A/zh active Pending
- 2018-11-16 JP JP2020545051A patent/JP2021503301A/ja active Pending
- 2018-11-16 EP EP18845327.8A patent/EP3710575A1/en active Pending
- 2018-11-16 US US16/194,278 patent/US20190307686A1/en not_active Abandoned
- 2018-11-16 EA EA202091219A patent/EA202091219A1/ru unknown
-
2020
- 2020-05-15 PH PH12020550660A patent/PH12020550660A1/en unknown
-
2023
- 2023-06-02 US US18/205,303 patent/US20230310319A1/en not_active Abandoned
- 2023-10-25 JP JP2023183102A patent/JP2024023185A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EA202091219A1 (ru) | 2020-08-18 |
AU2018370157A1 (en) | 2020-05-28 |
JP2021503301A (ja) | 2021-02-12 |
US20230310319A1 (en) | 2023-10-05 |
PH12020550660A1 (en) | 2021-04-26 |
JP2024023185A (ja) | 2024-02-21 |
EP3710575A1 (en) | 2020-09-23 |
SG11202004523SA (en) | 2020-06-29 |
US20190307686A1 (en) | 2019-10-10 |
CN111433352A (zh) | 2020-07-17 |
MA51649A (fr) | 2020-09-23 |
WO2019099955A1 (en) | 2019-05-23 |
CA3082880A1 (en) | 2019-05-23 |
KR20200083596A (ko) | 2020-07-08 |
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