MX2019008872A - Prevencion y tratamiento de da?o o enfermedad osea y cartilago. - Google Patents
Prevencion y tratamiento de da?o o enfermedad osea y cartilago.Info
- Publication number
- MX2019008872A MX2019008872A MX2019008872A MX2019008872A MX2019008872A MX 2019008872 A MX2019008872 A MX 2019008872A MX 2019008872 A MX2019008872 A MX 2019008872A MX 2019008872 A MX2019008872 A MX 2019008872A MX 2019008872 A MX2019008872 A MX 2019008872A
- Authority
- MX
- Mexico
- Prior art keywords
- bone
- prevention
- treatment
- disease
- cartilage damage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Botany (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
Abstract
Se describen composiciones y métodos para la prevención y/o tratamiento de condiciones que involucran enfermedad o daño en cartílago y hueso de mamífero, utilizando células madre mesenquimales aisladas con anticuerpos anti-integrina a10.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762451372P | 2017-01-27 | 2017-01-27 | |
PCT/EP2018/052104 WO2018138322A1 (en) | 2017-01-27 | 2018-01-29 | Prevention and treatment of bone and cartilage damage or disease |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019008872A true MX2019008872A (es) | 2019-09-18 |
Family
ID=61168072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019008872A MX2019008872A (es) | 2017-01-27 | 2018-01-29 | Prevencion y tratamiento de da?o o enfermedad osea y cartilago. |
Country Status (17)
Country | Link |
---|---|
US (2) | US11517593B2 (es) |
EP (2) | EP3573630B1 (es) |
JP (1) | JP7210829B2 (es) |
KR (1) | KR102580320B1 (es) |
CN (1) | CN110234329A (es) |
AU (1) | AU2018211504B2 (es) |
BR (1) | BR112019013508A2 (es) |
CA (1) | CA3050099C (es) |
DK (1) | DK3573630T3 (es) |
ES (1) | ES2870776T3 (es) |
IL (1) | IL266772B (es) |
LT (1) | LT3573630T (es) |
MX (1) | MX2019008872A (es) |
PL (1) | PL3573630T3 (es) |
PT (1) | PT3573630T (es) |
SG (1) | SG11201904535VA (es) |
WO (1) | WO2018138322A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112019025888A2 (pt) | 2017-06-07 | 2020-06-30 | Regeneron Pharmaceuticals, Inc. | polinucleotídeo que codifica uma proteína terapêutica multidomínio, vetor de terapia gênica, proteína terapêutica multidomínio recombinante, método de expressão, métodos para reduzir o acúmulo de glicogênio em um tecido em um paciente em necessidade, para reduzir o acúmulo de glicogênio em um tecido em um paciente em necessidade epara tratar a deficiência enzimática em um paciente em necessidade e/ou tolerar o paciente à enzima para a qual é deficiente, anticorpo anti-cd63 ou fragmento de ligação a antígeno, e, composição farmacêutica |
BR112020016005A2 (pt) | 2018-02-07 | 2020-12-15 | Regeneron Pharmaceuticals, Inc. | Método de administração de uma proteína terapêutica ao sistema nervoso central, proteína terapêutica multidomínio, polinucleotídeo, vetor de terapia gênica, e, uso de um nucleotídeo que codifica a proteína terapêutica multidomínio |
US20220380731A1 (en) * | 2019-11-08 | 2022-12-01 | Kansas State University Research Foundation | Isolation, preservation, and expansion of canine umbilical cord mesenchymal stromal cells |
CN112941021A (zh) * | 2020-03-13 | 2021-06-11 | 深圳市第二人民医院(深圳市转化医学研究院) | 一种骨关节炎关节液来源的间充质干细胞的培养方法 |
IL297902A (en) | 2020-05-07 | 2023-01-01 | Xintela Ab | Stem cells for the treatment of respiratory disorders |
CN113667635A (zh) * | 2020-05-14 | 2021-11-19 | 梦芊科技知识产权有限公司 | 无异源培养基及使用其扩增间充质干细胞的方法 |
CN112430269B (zh) * | 2021-01-28 | 2021-04-20 | 中赛干细胞基因工程有限公司 | 一种促进脐带血干细胞成骨分化的组合物及其应用 |
AU2022277806A1 (en) | 2021-05-20 | 2023-11-16 | Xintela Ab | Mesenchymal stem cells for use in the treatment of skin defects |
CN114540298A (zh) * | 2022-03-25 | 2022-05-27 | 北京瑷格干细胞科技有限公司 | 一种干细胞无血清培养基及其制备方法 |
WO2024077116A1 (en) * | 2022-10-05 | 2024-04-11 | Brim Biotechnology, Inc. | Compositions comprising pedf-derived short peptides and mesenchymal stem cells for bone/cartilage regeneration |
CN115651076B (zh) * | 2022-12-09 | 2023-09-29 | 北京大学口腔医学院 | 人骨髓间充质干细胞来源凋亡囊泡的表面标志物及其应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2353061T5 (es) * | 2000-04-25 | 2014-04-07 | Osiris Therapeutics, Inc. | Reparación de articulaciones utilizando células madre mesenquimatosas |
JP4399533B2 (ja) * | 2002-06-14 | 2010-01-20 | キシンテラ、アクチボラグ | 幹細胞のマーカーおよびその使用 |
SE0301087D0 (sv) * | 2003-04-14 | 2003-04-14 | Cartela Ab | New monoclonal antibody |
WO2007099337A1 (en) * | 2006-03-01 | 2007-09-07 | Cartela R&D Ab | Expansion and differentiation of mesenchymal stem cells |
WO2008072000A2 (en) | 2006-12-15 | 2008-06-19 | Xintela Ab (Se) | Use of integrin alpha 10 binding antibody to modulate extracellular matrix ( cartilage) turnover |
WO2009015343A2 (en) * | 2007-07-25 | 2009-01-29 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to chondrocytes |
-
2018
- 2018-01-29 DK DK18703531.6T patent/DK3573630T3/da active
- 2018-01-29 EP EP18703531.6A patent/EP3573630B1/en active Active
- 2018-01-29 LT LTEP18703531.6T patent/LT3573630T/lt unknown
- 2018-01-29 WO PCT/EP2018/052104 patent/WO2018138322A1/en active Search and Examination
- 2018-01-29 BR BR112019013508-1A patent/BR112019013508A2/pt unknown
- 2018-01-29 CA CA3050099A patent/CA3050099C/en active Active
- 2018-01-29 SG SG11201904535VA patent/SG11201904535VA/en unknown
- 2018-01-29 ES ES18703531T patent/ES2870776T3/es active Active
- 2018-01-29 MX MX2019008872A patent/MX2019008872A/es unknown
- 2018-01-29 PT PT187035316T patent/PT3573630T/pt unknown
- 2018-01-29 JP JP2019535889A patent/JP7210829B2/ja active Active
- 2018-01-29 KR KR1020197022614A patent/KR102580320B1/ko active IP Right Grant
- 2018-01-29 AU AU2018211504A patent/AU2018211504B2/en active Active
- 2018-01-29 CN CN201880008965.1A patent/CN110234329A/zh active Pending
- 2018-01-29 PL PL18703531T patent/PL3573630T3/pl unknown
- 2018-01-29 EP EP21162806.0A patent/EP3919064A1/en not_active Withdrawn
-
2019
- 2019-05-21 IL IL266772A patent/IL266772B/en unknown
- 2019-07-23 US US16/519,179 patent/US11517593B2/en active Active
-
2022
- 2022-11-01 US US17/978,300 patent/US20230128397A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2018211504B2 (en) | 2022-08-18 |
KR102580320B1 (ko) | 2023-09-19 |
CN110234329A (zh) | 2019-09-13 |
WO2018138322A1 (en) | 2018-08-02 |
BR112019013508A2 (pt) | 2020-01-07 |
JP7210829B2 (ja) | 2023-01-24 |
KR20190107686A (ko) | 2019-09-20 |
DK3573630T3 (da) | 2021-06-07 |
SG11201904535VA (en) | 2019-08-27 |
PT3573630T (pt) | 2021-05-06 |
PL3573630T3 (pl) | 2021-09-13 |
JP2020505916A (ja) | 2020-02-27 |
US20230128397A1 (en) | 2023-04-27 |
IL266772B (en) | 2022-04-01 |
ES2870776T3 (es) | 2021-10-27 |
AU2018211504A1 (en) | 2019-07-04 |
EP3919064A1 (en) | 2021-12-08 |
IL266772A (en) | 2019-07-31 |
CA3050099A1 (en) | 2018-08-02 |
EP3573630A1 (en) | 2019-12-04 |
EP3573630B1 (en) | 2021-03-17 |
US20200038449A1 (en) | 2020-02-06 |
US11517593B2 (en) | 2022-12-06 |
LT3573630T (lt) | 2021-05-25 |
CA3050099C (en) | 2024-04-16 |
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