MX2019008390A - Compounds useful for treating cancer. - Google Patents

Compounds useful for treating cancer.

Info

Publication number
MX2019008390A
MX2019008390A MX2019008390A MX2019008390A MX2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A MX 2019008390 A MX2019008390 A MX 2019008390A
Authority
MX
Mexico
Prior art keywords
group
alkyl
treating cancer
hydroxyl
compounds useful
Prior art date
Application number
MX2019008390A
Other languages
Spanish (es)
Inventor
Roux Pierre
Mahuteau Florence
Najman Romain
Scherrer Didier
Brock Carsten
Cahuzac Nathalie
Gadea Gilles
Tazi Jamal
Original Assignee
Abivax
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP20090305540 external-priority patent/EP2266972A1/en
Priority claimed from EP09162630A external-priority patent/EP2261214A1/en
Application filed by Abivax filed Critical Abivax
Publication of MX2019008390A publication Critical patent/MX2019008390A/en

Links

Abstract

The present invention relates to compound (I) wherein: means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a CN group, a hydroxyl group, a COOR1 group, a (C1-C3)fluoroalkyl group, a (C1-C3)fluoroalkoxy group, a NO2 group, a NR1R2 group, a (C1-C4)alkoxy group, a phenoxy group and a (C1-C3)alkyl group, said alkyl being optionally mono-substituted by a hydroxyl group, n is 1, 2 or 3, n is 1 or 2, R is a hydrogen atom, a halogen atom or a group chosen among a (C1-C3)alkyl group,, a hydroxyl group, a COOR1 group, a NO2 group, a NR1R2 group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C1-C3)fluoroalkyl group, a (C1-C4)alkoxy group and a CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating cancer. Some of said compounds are new and also form part of the invention.
MX2019008390A 2009-06-12 2011-12-07 Compounds useful for treating cancer. MX2019008390A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18654409P 2009-06-12 2009-06-12
US18655209P 2009-06-12 2009-06-12
EP20090305540 EP2266972A1 (en) 2009-06-12 2009-06-12 New chemical molecules that inhibit the splicing mechanism for treating diseases resulting from splicing anomalies
EP09162630A EP2261214A1 (en) 2009-06-12 2009-06-12 Compounds useful to treat premature aging and in particular progeria

Publications (1)

Publication Number Publication Date
MX2019008390A true MX2019008390A (en) 2019-09-09

Family

ID=56384060

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019008390A MX2019008390A (en) 2009-06-12 2011-12-07 Compounds useful for treating cancer.

Country Status (3)

Country Link
JP (11) JP6149128B2 (en)
HR (1) HRP20191460T1 (en)
MX (1) MX2019008390A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253020B2 (en) 2009-06-12 2019-04-09 Abivax Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging
KR102016892B1 (en) * 2009-06-12 2019-08-30 아비박스 Compounds useful for treating premature aging in particular progeria
MX2019008390A (en) * 2009-06-12 2019-09-09 Abivax Compounds useful for treating cancer.
EP2757161A1 (en) 2013-01-17 2014-07-23 Splicos miRNA-124 as a biomarker of viral infection
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
WO2021070384A1 (en) 2019-10-11 2021-04-15 日本製鉄株式会社 High-strength steel member
TW202333698A (en) * 2022-01-24 2023-09-01 大陸商江蘇恆瑞醫藥股份有限公司 Quinoline amine compounds, preparation method and medical use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE958647C (en) * 1952-12-28 1957-02-21 Hoechst Ag Process for the preparation of 7-amino-2-oxy-4-methyl-quinolines
US6177401B1 (en) * 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
PL373301A1 (en) * 2001-01-22 2005-08-22 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors
AU2002950217A0 (en) * 2002-07-16 2002-09-12 Prana Biotechnology Limited 8- Hydroxy Quinoline Derivatives
FR2912745A1 (en) * 2007-02-19 2008-08-22 Centre Nat Rech Scient NEW INDOLE-DERIVED COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO2008115870A2 (en) * 2007-03-16 2008-09-25 Mount Sinai School Of Medicine Induction and/or maintenance of tumor dormancy by disruption of urokinase plasminogen activator receptor-integrin interaction
KR102016892B1 (en) * 2009-06-12 2019-08-30 아비박스 Compounds useful for treating premature aging in particular progeria
MX2019008390A (en) * 2009-06-12 2019-09-09 Abivax Compounds useful for treating cancer.

Also Published As

Publication number Publication date
JP2017137342A (en) 2017-08-10
HRP20191460T1 (en) 2019-11-15
JP6149128B2 (en) 2017-06-14
JP2016128462A (en) 2016-07-14
JP6419243B2 (en) 2018-11-07
JP6378802B2 (en) 2018-08-22
JP2016135776A (en) 2016-07-28
JP2018162290A (en) 2018-10-18
JP6149129B2 (en) 2017-06-14
JP2016128463A (en) 2016-07-14
JP6149127B2 (en) 2017-06-14
JP2017222639A (en) 2017-12-21
JP2016147850A (en) 2016-08-18
JP2018162291A (en) 2018-10-18
JP6336650B2 (en) 2018-06-06
JP6694476B2 (en) 2020-05-13
JP6606577B2 (en) 2019-11-13
JP6150445B2 (en) 2017-06-21
JP2016128461A (en) 2016-07-14
JP2017137341A (en) 2017-08-10
JP6154922B2 (en) 2017-06-28
JP2018162292A (en) 2018-10-18

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