MX2019007766A - Variantes de enzima con propiedades de ester sintasa mejoradas. - Google Patents
Variantes de enzima con propiedades de ester sintasa mejoradas.Info
- Publication number
- MX2019007766A MX2019007766A MX2019007766A MX2019007766A MX2019007766A MX 2019007766 A MX2019007766 A MX 2019007766A MX 2019007766 A MX2019007766 A MX 2019007766A MX 2019007766 A MX2019007766 A MX 2019007766A MX 2019007766 A MX2019007766 A MX 2019007766A
- Authority
- MX
- Mexico
- Prior art keywords
- enzyme variants
- ester synthase
- host cells
- improved ester
- recombinant host
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 2
- 108090000790 Enzymes Proteins 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- -1 fatty acid esters Chemical class 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/01—Methyltransferases (2.1.1)
- C12Y201/01015—Fatty-acid O-methyltransferase (2.1.1.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01067—Fatty-acyl-ethyl-ester synthase (3.1.1.67)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/02—Thioester hydrolases (3.1.2)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P30/00—Technologies relating to oil refining and petrochemical industry
- Y02P30/20—Technologies relating to oil refining and petrochemical industry using bio-feedstock
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La descripción se refiere a variantes de enzima con propiedades de éster sintasa mejoradas para la producción de ésteres de ácido graso. Además, se contemplan células hospederas recombinantes que expresan tales variantes, cultivos celulares que comprenden las células hospederas recombinantes y composiciones de éster de ácido graso producido por tales células hospederas recombinantes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261701191P | 2012-09-14 | 2012-09-14 | |
US201261708424P | 2012-10-01 | 2012-10-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019007766A true MX2019007766A (es) | 2019-10-15 |
Family
ID=48045767
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015003305A MX366179B (es) | 2012-09-14 | 2013-03-15 | Variantes de enzima con propiedades de ester sintasa mejoradas. |
MX2019007766A MX2019007766A (es) | 2012-09-14 | 2015-03-13 | Variantes de enzima con propiedades de ester sintasa mejoradas. |
MX2022002057A MX2022002057A (es) | 2012-09-14 | 2015-03-13 | Variantes de enzima con propiedades de ester sintasa mejoradas. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015003305A MX366179B (es) | 2012-09-14 | 2013-03-15 | Variantes de enzima con propiedades de ester sintasa mejoradas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022002057A MX2022002057A (es) | 2012-09-14 | 2015-03-13 | Variantes de enzima con propiedades de ester sintasa mejoradas. |
Country Status (11)
Country | Link |
---|---|
US (3) | US9879239B2 (es) |
EP (2) | EP2895602B1 (es) |
JP (6) | JP6401703B2 (es) |
KR (4) | KR20230020007A (es) |
CN (2) | CN112899250A (es) |
AU (3) | AU2013316124C1 (es) |
BR (1) | BR112015005782A2 (es) |
CA (2) | CA3079799A1 (es) |
ES (1) | ES2647412T3 (es) |
MX (3) | MX366179B (es) |
WO (1) | WO2014042693A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2015001780A (es) | 2012-08-10 | 2015-09-28 | Opx Biotechnologies Inc | Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos. |
WO2014146026A1 (en) | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
CN106795483A (zh) | 2013-07-19 | 2017-05-31 | 嘉吉公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
EP2993228B1 (en) * | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
WO2018144701A2 (en) | 2017-02-02 | 2018-08-09 | Cargill Incorporated | Genetically modified cells that produce c6-c10 fatty acid derivatives |
CN111094558A (zh) * | 2017-04-03 | 2020-05-01 | 基因组股份公司 | 对产生中链脂肪酸衍生物具有改善的活性的硫酯酶变体 |
MX2022002473A (es) * | 2019-08-30 | 2022-08-02 | Codexis Inc | Variantes de lipasa modificadas geneticamente. |
WO2023178193A1 (en) | 2022-03-16 | 2023-09-21 | Genomatica, Inc. | Acyl-acp thioesterase variants and uses thereof |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7791991A (en) | 1990-04-24 | 1991-11-11 | Stratagene | Methods for phenotype creation from multiple gene populations |
US6428767B1 (en) | 1995-05-12 | 2002-08-06 | E. I. Du Pont De Nemours And Company | Method for identifying the source of carbon in 1,3-propanediol |
US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
TW200510535A (en) | 2003-02-21 | 2005-03-16 | Kaneka Corp | Novel vector |
BRPI0513438A2 (pt) | 2004-07-16 | 2011-01-04 | Danisco | método enzimático para degomagem de óleo |
US7897369B2 (en) * | 2007-08-27 | 2011-03-01 | Regents Of The University Of Minnesota | Isoprenoid wax ester synthases, isoprenoid acyl CoA-synthetases, and uses thereof |
WO2010042664A2 (en) * | 2008-10-07 | 2010-04-15 | Ls9, Inc. | Method and compositions for producing fatty aldehydes |
US9175234B2 (en) * | 2008-12-23 | 2015-11-03 | REG Life Sciences, LLC | Methods and compositions related to thioesterase enzymes |
CA2774975C (en) * | 2009-09-25 | 2019-11-05 | Ls9, Inc. | Production of fatty acid derivatives in recombinant bacterial cells expressing an ester synthase variant |
JP2011103863A (ja) | 2009-11-20 | 2011-06-02 | National Institute For Agro-Environmental Science | デオキシニバレノールの分解活性を有するタンパク質をコードする遺伝子 |
US8530221B2 (en) * | 2010-01-14 | 2013-09-10 | Ls9, Inc. | Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells |
DK2601292T3 (en) * | 2010-08-06 | 2018-07-16 | Biopetrolia Ab | METHODS AND PRODUCTS FOR MANUFACTURING GROWERS |
WO2013048557A1 (en) | 2011-09-27 | 2013-04-04 | Exxonmobil Research And Engineering Company | Acyl-acp wax ester synthases |
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2013
- 2013-03-15 US US14/424,387 patent/US9879239B2/en active Active
- 2013-03-15 EP EP13714142.0A patent/EP2895602B1/en active Active
- 2013-03-15 KR KR1020237002999A patent/KR20230020007A/ko not_active Application Discontinuation
- 2013-03-15 ES ES13714142.0T patent/ES2647412T3/es active Active
- 2013-03-15 BR BR112015005782A patent/BR112015005782A2/pt not_active Application Discontinuation
- 2013-03-15 AU AU2013316124A patent/AU2013316124C1/en active Active
- 2013-03-15 CN CN202110142262.1A patent/CN112899250A/zh active Pending
- 2013-03-15 MX MX2015003305A patent/MX366179B/es active IP Right Grant
- 2013-03-15 KR KR1020157009459A patent/KR102072048B1/ko active IP Right Grant
- 2013-03-15 KR KR1020217040434A patent/KR102493733B1/ko active IP Right Grant
- 2013-03-15 KR KR1020207002289A patent/KR102339617B1/ko active IP Right Grant
- 2013-03-15 CA CA3079799A patent/CA3079799A1/en active Pending
- 2013-03-15 JP JP2015531914A patent/JP6401703B2/ja active Active
- 2013-03-15 CA CA2885041A patent/CA2885041C/en active Active
- 2013-03-15 WO PCT/US2013/032564 patent/WO2014042693A1/en active Application Filing
- 2013-03-15 EP EP17187284.9A patent/EP3299455A1/en active Pending
- 2013-03-15 CN CN201380058918.5A patent/CN104955944B/zh active Active
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2015
- 2015-03-13 MX MX2019007766A patent/MX2019007766A/es unknown
- 2015-03-13 MX MX2022002057A patent/MX2022002057A/es unknown
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2018
- 2018-01-18 US US15/873,977 patent/US10894953B2/en active Active
- 2018-09-07 JP JP2018168156A patent/JP6820888B2/ja active Active
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2019
- 2019-04-12 AU AU2019202572A patent/AU2019202572B2/en active Active
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2020
- 2020-02-12 JP JP2020021255A patent/JP7068362B2/ja active Active
- 2020-02-12 JP JP2020021247A patent/JP7030145B2/ja active Active
- 2020-10-08 JP JP2020170577A patent/JP2021003131A/ja active Pending
- 2020-12-09 US US17/116,817 patent/US20210309979A1/en not_active Abandoned
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2022
- 2022-01-11 AU AU2022200123A patent/AU2022200123A1/en active Pending
- 2022-02-07 JP JP2022016860A patent/JP2022051839A/ja not_active Withdrawn
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