MX2019000263A - Metodo para reducir una cantidad de particulas subvisibles en una composicion farmaceutica. - Google Patents
Metodo para reducir una cantidad de particulas subvisibles en una composicion farmaceutica.Info
- Publication number
- MX2019000263A MX2019000263A MX2019000263A MX2019000263A MX2019000263A MX 2019000263 A MX2019000263 A MX 2019000263A MX 2019000263 A MX2019000263 A MX 2019000263A MX 2019000263 A MX2019000263 A MX 2019000263A MX 2019000263 A MX2019000263 A MX 2019000263A
- Authority
- MX
- Mexico
- Prior art keywords
- barrel
- pharmaceutical composition
- reducing
- amount
- subvisible particles
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000012906 subvisible particle Substances 0.000 title abstract 2
- 239000000314 lubricant Substances 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010999 medical injection Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31513—Piston constructions to improve sealing or sliding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D3/00—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
- B05D3/007—After-treatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D3/00—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
- B05D3/14—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by electrical means
- B05D3/141—Plasma treatment
- B05D3/145—After-treatment
- B05D3/148—After-treatment affecting the surface properties of the coating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D5/00—Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31516—Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0222—Materials for reducing friction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Materials For Medical Uses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
La invención de interés describe un método para reducir una cantidad de partículas subvisibles en una composición farmacéutica contenida en un dispositivo de inyección médico que comprende un contenedor (1) que incluye un cilindro (10) lubricado con un revestimiento lubricante (2) en contacto con la composición farmacéutica y un tapón (14) en acoplamiento deslizante dentro del cilindro (10), el contenedor comprende una región (130, 121, 123) que se extiende distalmente desde el extremo distal (100) del cilindro que no es accesible al tapón. Durante la formación de dicho recubrimiento lubricante (2) en la pared interior del cilindro, el método además comprende limitar al lubricante de depositarse en dicha región (130, 121, 123) que se extiende distalmente desde el extremo distal (100) del cilindro.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16305874 | 2016-07-11 | ||
PCT/EP2017/067368 WO2018011190A1 (en) | 2016-07-11 | 2017-07-11 | Method for reducing an amount of subvisible particles in a pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019000263A true MX2019000263A (es) | 2019-05-27 |
Family
ID=56567544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019000263A MX2019000263A (es) | 2016-07-11 | 2017-07-11 | Metodo para reducir una cantidad de particulas subvisibles en una composicion farmaceutica. |
Country Status (7)
Country | Link |
---|---|
US (2) | US11628257B2 (es) |
EP (1) | EP3481467A1 (es) |
JP (2) | JP7042792B2 (es) |
KR (1) | KR102372106B1 (es) |
CN (2) | CN107596503A (es) |
MX (1) | MX2019000263A (es) |
WO (1) | WO2018011190A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101452136B1 (ko) * | 2013-10-01 | 2014-10-16 | 주식회사 포스코건설 | 건축구조물의 방수 보호 장치 |
JP7164997B2 (ja) | 2018-08-31 | 2022-11-02 | Ntn株式会社 | 塗布針部材、塗布針部材アセンブリ、塗布部材および塗布装置 |
FR3093004B1 (fr) * | 2019-02-21 | 2023-04-07 | Dev Techniques Plastiques | Procede de preparation d’une seringue |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4022206A (en) * | 1975-08-01 | 1977-05-10 | Merck & Co., Inc. | Vaccine delivery system |
US5456940A (en) | 1994-03-28 | 1995-10-10 | Minimed Inc. | System for lubricating a syringe barrel |
DE19753766A1 (de) * | 1997-12-04 | 1999-06-17 | Schott Glas | Länglicher Kunststoff-Hohlkörper und Verfahren zu seiner Herstellung |
US6461334B1 (en) | 1998-03-06 | 2002-10-08 | Novo Nordisk A/S | Medical article with coated surfaces exhibiting low friction and protein adsorption |
DE10036832C1 (de) * | 2000-07-28 | 2001-12-13 | Schott Glas | Verfahren und Vorrichtung zum Aufbringen einer hitzefixierten Gleitmittelschicht auf die Innenwandung von zylindrischen Behältern für medizinische Zwecke |
JP2004229750A (ja) * | 2003-01-28 | 2004-08-19 | Nipro Corp | プレフィルドシリンジ及びそのバレルの製造方法 |
JP2005160888A (ja) | 2003-12-05 | 2005-06-23 | Terumo Corp | シリンジ用ガスケット、シリンジ及びシリンジ用ガスケットの製造方法 |
JP5647126B2 (ja) | 2008-09-22 | 2014-12-24 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 光分解化学的気相堆積法および/または熱化学的気相堆積法を使用して容器の内部を被覆するシステム、装置および方法 |
TWI543790B (zh) * | 2008-12-03 | 2016-08-01 | Denka Company Ltd | syringe |
WO2011052115A1 (ja) * | 2009-10-28 | 2011-05-05 | 味の素株式会社 | シリンジとシリンジ本体の製造装置とシリンジ本体の製造方法 |
WO2011092536A1 (en) * | 2010-01-26 | 2011-08-04 | Becton Dickinson France | Drug cartrigde different inner surface conditions |
CN103957966B (zh) * | 2011-09-27 | 2017-09-29 | 贝克顿迪金森法国公司 | 等离子体处理过的硅油作为医用注射装置中的涂层的用途 |
WO2013167617A2 (en) | 2012-05-07 | 2013-11-14 | Becton Dickinson France | Lubricant coating for medical container |
EP3910046B1 (en) * | 2012-05-29 | 2022-11-30 | Becton Dickinson France | Process for manufacturing a lubricant coating |
CA2949881A1 (en) | 2014-05-26 | 2015-12-03 | Becton Dickinson France | Method for storing an emulsion-adjuvanted vaccine in a lubricated medical injection device |
WO2016102068A1 (en) | 2014-12-23 | 2016-06-30 | Merz Pharma Gmbh & Co. Kgaa | Botulinum toxin prefilled container |
-
2017
- 2017-07-11 WO PCT/EP2017/067368 patent/WO2018011190A1/en unknown
- 2017-07-11 KR KR1020197003776A patent/KR102372106B1/ko active IP Right Grant
- 2017-07-11 EP EP17737283.6A patent/EP3481467A1/en active Pending
- 2017-07-11 MX MX2019000263A patent/MX2019000263A/es unknown
- 2017-07-11 CN CN201710559852.8A patent/CN107596503A/zh active Pending
- 2017-07-11 JP JP2019500789A patent/JP7042792B2/ja active Active
- 2017-07-11 CN CN202310980324.5A patent/CN116870298A/zh active Pending
- 2017-07-11 US US16/316,736 patent/US11628257B2/en active Active
-
2021
- 2021-12-28 JP JP2021214514A patent/JP2022046705A/ja active Pending
-
2023
- 2023-03-16 US US18/122,430 patent/US20230218830A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR102372106B1 (ko) | 2022-03-08 |
JP7042792B2 (ja) | 2022-03-28 |
WO2018011190A1 (en) | 2018-01-18 |
US20230218830A1 (en) | 2023-07-13 |
JP2022046705A (ja) | 2022-03-23 |
US20190290856A1 (en) | 2019-09-26 |
CN116870298A (zh) | 2023-10-13 |
JP2019521781A (ja) | 2019-08-08 |
KR20190029637A (ko) | 2019-03-20 |
CN107596503A (zh) | 2018-01-19 |
EP3481467A1 (en) | 2019-05-15 |
US11628257B2 (en) | 2023-04-18 |
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