MX2018006610A - Nuevos peptidos que tienen actividad antimicrobiana y nueva enzima capaces de convertir un residuo de configuracion l en un aminoacido de configuracion d en un peptido. - Google Patents

Nuevos peptidos que tienen actividad antimicrobiana y nueva enzima capaces de convertir un residuo de configuracion l en un aminoacido de configuracion d en un peptido.

Info

Publication number
MX2018006610A
MX2018006610A MX2018006610A MX2018006610A MX2018006610A MX 2018006610 A MX2018006610 A MX 2018006610A MX 2018006610 A MX2018006610 A MX 2018006610A MX 2018006610 A MX2018006610 A MX 2018006610A MX 2018006610 A MX2018006610 A MX 2018006610A
Authority
MX
Mexico
Prior art keywords
new
peptide
amino acid
residue
converting
Prior art date
Application number
MX2018006610A
Other languages
English (en)
Inventor
Benjdia Alhosna
Guillot Alain
Berteau Olivier
Original Assignee
Inst Nat De La Rech Agronomique Inra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat De La Rech Agronomique Inra filed Critical Inst Nat De La Rech Agronomique Inra
Publication of MX2018006610A publication Critical patent/MX2018006610A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a una nueva clase de péptidos que tienen actividad antibacteriana y presentes en aminoácidos D y a sus usos. También se refiere a una nueva enzima que presenta actividad epimerasa peptídica in vitro e in vivo, siendo útil para modificar péptidos con el fin de cambiar la configuración del aminoácido de L a D.
MX2018006610A 2015-12-02 2016-12-01 Nuevos peptidos que tienen actividad antimicrobiana y nueva enzima capaces de convertir un residuo de configuracion l en un aminoacido de configuracion d en un peptido. MX2018006610A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15306909 2015-12-02
EP16183955 2016-08-12
PCT/EP2016/079362 WO2017093366A1 (en) 2015-12-02 2016-12-01 New peptides having antimicrobial activity and new enzyme capable of converting l-configured residue in d-configured amino acid in a peptide

Publications (1)

Publication Number Publication Date
MX2018006610A true MX2018006610A (es) 2019-05-27

Family

ID=57482394

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018006610A MX2018006610A (es) 2015-12-02 2016-12-01 Nuevos peptidos que tienen actividad antimicrobiana y nueva enzima capaces de convertir un residuo de configuracion l en un aminoacido de configuracion d en un peptido.

Country Status (7)

Country Link
US (1) US10981957B2 (es)
JP (1) JP2019500338A (es)
CN (1) CN108368158A (es)
BR (1) BR112018011096A2 (es)
CA (1) CA3006403A1 (es)
MX (1) MX2018006610A (es)
WO (1) WO2017093366A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71691A (en) 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
US5047335A (en) 1988-12-21 1991-09-10 The Regents Of The University Of Calif. Process for controlling intracellular glycosylation of proteins
FR2704860B1 (fr) 1993-05-05 1995-07-13 Pasteur Institut Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire.
WO1996000787A1 (en) 1994-06-30 1996-01-11 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
US5955310A (en) 1998-02-26 1999-09-21 Novo Nordisk Biotech, Inc. Methods for producing a polypeptide in a bacillus cell
DE69932345T2 (de) 1998-10-26 2007-07-19 Novozymes A/S Erstellung und durchmusterung von interessierenden dna-banken in zellen von filamentösen pilzen
WO2000056900A2 (en) 1999-03-22 2000-09-28 Novo Nordisk Biotech, Inc. Promoter sequences derived from fusarium venenatum and uses thereof
US20060121083A1 (en) 2003-07-18 2006-06-08 Technion Research & Development Foundation Ltd. Anti-microbial medical implants and uses thereof
US7148404B2 (en) * 2004-05-04 2006-12-12 Novozymes A/S Antimicrobial polypeptides
US20070184015A1 (en) 2006-02-03 2007-08-09 Soonkap Hahn Novel PEGylation agent
KR102274003B1 (ko) * 2007-01-19 2021-07-08 카이 파마슈티컬즈 안정성 및 전달 효율을 증가시키기 위한 펩타이드 조성물의 변형

Also Published As

Publication number Publication date
JP2019500338A (ja) 2019-01-10
CN108368158A (zh) 2018-08-03
US10981957B2 (en) 2021-04-20
BR112018011096A2 (pt) 2018-12-04
WO2017093366A1 (en) 2017-06-08
CA3006403A1 (en) 2017-06-08
US20180346526A1 (en) 2018-12-06

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