MX2017011838A - Composiciones y metodos para tratar carcinoma hepatocelular. - Google Patents

Composiciones y metodos para tratar carcinoma hepatocelular.

Info

Publication number
MX2017011838A
MX2017011838A MX2017011838A MX2017011838A MX2017011838A MX 2017011838 A MX2017011838 A MX 2017011838A MX 2017011838 A MX2017011838 A MX 2017011838A MX 2017011838 A MX2017011838 A MX 2017011838A MX 2017011838 A MX2017011838 A MX 2017011838A
Authority
MX
Mexico
Prior art keywords
methods
hepatocellular carcinoma
compositions
treating hepatocellular
treating
Prior art date
Application number
MX2017011838A
Other languages
English (en)
Inventor
Chen Zhi
Huang Sui
Lou Guohua
Green Richard
Wang Chen
Norton John
Liu Yanning
Original Assignee
Univ Northwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern filed Critical Univ Northwestern
Publication of MX2017011838A publication Critical patent/MX2017011838A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporcionan en la presente composiciones y métodos para tratar, mejorar, o prevenir carcinoma hepatocelular en pacientes. En particular, la invención se refiere a métodos para tratar, mejorar, o prevenir carcinoma hepatocelular en un paciente, que comprende la administración al paciente de 6-metoxietilamino-numon afida sola o en combinación con sorafenib.
MX2017011838A 2015-03-19 2016-03-18 Composiciones y metodos para tratar carcinoma hepatocelular. MX2017011838A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562135435P 2015-03-19 2015-03-19
PCT/US2016/023212 WO2016149647A1 (en) 2015-03-19 2016-03-18 Compositions and methods for treating hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
MX2017011838A true MX2017011838A (es) 2018-06-06

Family

ID=56919582

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017011838A MX2017011838A (es) 2015-03-19 2016-03-18 Composiciones y metodos para tratar carcinoma hepatocelular.

Country Status (7)

Country Link
US (2) US20180110743A1 (es)
EP (1) EP3270919A4 (es)
JP (1) JP2018508546A (es)
AU (1) AU2016232775A1 (es)
CA (1) CA2979843A1 (es)
MX (1) MX2017011838A (es)
WO (1) WO2016149647A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5341081B2 (ja) * 2007-07-25 2013-11-13 アルマ マーテル ステューディオラム − ウニヴェルスィタ ディ ボローニャ 肝細胞癌処置用医薬組成物および医薬キット
JP6205373B2 (ja) * 2012-02-03 2017-09-27 ザ・ジョンズ・ホプキンス・ユニバーシティ Ndga誘導体およびソラフェニブを含む組成物、ならびにがんの処置におけるこれらの使用
CN104257655B (zh) * 2014-08-31 2016-06-22 浙江大学 化合物mean在制备抑制hcv复制的药物中的用途

Also Published As

Publication number Publication date
JP2018508546A (ja) 2018-03-29
AU2016232775A1 (en) 2017-10-12
US20190374485A1 (en) 2019-12-12
CA2979843A1 (en) 2016-09-22
EP3270919A1 (en) 2018-01-24
WO2016149647A1 (en) 2016-09-22
US20180110743A1 (en) 2018-04-26
EP3270919A4 (en) 2018-10-24

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