MX2017003366A - Regimenes de dosificacion y métodos especificos para el tratamiento de la depresión con el genotipo val66met (snp rs6265). - Google Patents

Regimenes de dosificacion y métodos especificos para el tratamiento de la depresión con el genotipo val66met (snp rs6265).

Info

Publication number
MX2017003366A
MX2017003366A MX2017003366A MX2017003366A MX2017003366A MX 2017003366 A MX2017003366 A MX 2017003366A MX 2017003366 A MX2017003366 A MX 2017003366A MX 2017003366 A MX2017003366 A MX 2017003366A MX 2017003366 A MX2017003366 A MX 2017003366A
Authority
MX
Mexico
Prior art keywords
treatment
depression
val66met
methods
dosing regimens
Prior art date
Application number
MX2017003366A
Other languages
English (en)
Inventor
Jaskaran Singh
Lodewijk Ivo Caers
SALVADORE Giacomo
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54200096&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017003366(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2017003366A publication Critical patent/MX2017003366A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención está dirigida a métodos y regímenes de dosificación para el tratamiento de la depresión (preferentemente, la depresión resistente al tratamiento), para el tratamiento de la depresión en un paciente suicida y/o para el tratamiento y/o la prevención de la tendencia al suicidio (p. ej., ideaciones suicidas), que comprenden el genotipaje de un paciente para determinar su polimorfismo Va166Met rs6265 en el BDNF y la administración de una ketamina, preferentemente esketamina, preferentemente esketamina intranasal, de conformidad con un régimen de dosificación adaptado al genotipo del paciente.
MX2017003366A 2014-09-15 2015-09-14 Regimenes de dosificacion y métodos especificos para el tratamiento de la depresión con el genotipo val66met (snp rs6265). MX2017003366A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462050439P 2014-09-15 2014-09-15
PCT/US2015/049961 WO2016044150A1 (en) 2014-09-15 2015-09-14 VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION

Publications (1)

Publication Number Publication Date
MX2017003366A true MX2017003366A (es) 2018-02-01

Family

ID=54200096

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017003366A MX2017003366A (es) 2014-09-15 2015-09-14 Regimenes de dosificacion y métodos especificos para el tratamiento de la depresión con el genotipo val66met (snp rs6265).

Country Status (11)

Country Link
US (5) US20160074340A1 (es)
EP (2) EP3193853A1 (es)
JP (2) JP2017528483A (es)
KR (1) KR20170054470A (es)
CN (1) CN107208133A (es)
AU (1) AU2015318123A1 (es)
CA (1) CA2961208A1 (es)
IL (2) IL251068A0 (es)
MA (1) MA40620A (es)
MX (1) MX2017003366A (es)
WO (1) WO2016044150A1 (es)

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JP2022546456A (ja) * 2019-08-28 2022-11-04 ヤンセン ファーマシューティカルズ，インコーポレーテッド 自殺傾向を含む大うつ病性障害を有する患者の治療のためのエスケタミン
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Also Published As

Publication number Publication date
AU2015318123A1 (en) 2017-03-30
US20230089113A1 (en) 2023-03-23
US20200246279A1 (en) 2020-08-06
US20210106545A1 (en) 2021-04-15
EP3725307A1 (en) 2020-10-21
IL279119A (en) 2021-01-31
WO2016044150A1 (en) 2016-03-24
JP2017528483A (ja) 2017-09-28
CN107208133A (zh) 2017-09-26
KR20170054470A (ko) 2017-05-17
US11311500B2 (en) 2022-04-26
JP2021054829A (ja) 2021-04-08
US20210308076A1 (en) 2021-10-07
CA2961208A1 (en) 2016-03-24
US11173134B2 (en) 2021-11-16
IL251068A0 (en) 2017-04-30
US20160074340A1 (en) 2016-03-17
US10869844B2 (en) 2020-12-22
EP3193853A1 (en) 2017-07-26
MA40620A (fr) 2016-03-24

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