MX2017000630A - Regimenes de sensibilización-refuerzo con un adyuvante de agonista tlr4 y un vector lentiviral. - Google Patents
Regimenes de sensibilización-refuerzo con un adyuvante de agonista tlr4 y un vector lentiviral.Info
- Publication number
- MX2017000630A MX2017000630A MX2017000630A MX2017000630A MX2017000630A MX 2017000630 A MX2017000630 A MX 2017000630A MX 2017000630 A MX2017000630 A MX 2017000630A MX 2017000630 A MX2017000630 A MX 2017000630A MX 2017000630 A MX2017000630 A MX 2017000630A
- Authority
- MX
- Mexico
- Prior art keywords
- prime
- lentiviral vector
- tlr4 agonist
- immune response
- boost regimens
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 230000028996 humoral immune response Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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Abstract
La presente invención se refiere a composiciones y métodos para estrategias de inmunización dual mejoradas que inducen en un sujeto, una respuesta inmune robusta. Los métodos descritos son por lo tanto, útiles para tratar y/o prevenir (es decir, reducir la probabilidad o riesgo de aparición) diferentes enfermedades, trastornos y condiciones tales como cánceres y enfermedades infecciosas para las cuales se desea y es benéfica, la inducción de una respuesta inmune humoral y/o respuesta inmune celular. 15.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462024792P | 2014-07-15 | 2014-07-15 | |
US201462024797P | 2014-07-15 | 2014-07-15 | |
PCT/US2015/040453 WO2016011083A1 (en) | 2014-07-15 | 2015-07-14 | Prime-boost regimens with a tlr4 agonist adjuvant and a lentiviral vector |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017000630A true MX2017000630A (es) | 2017-04-27 |
Family
ID=53776968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017000630A MX2017000630A (es) | 2014-07-15 | 2015-07-14 | Regimenes de sensibilización-refuerzo con un adyuvante de agonista tlr4 y un vector lentiviral. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20170196954A1 (es) |
EP (1) | EP3169352A1 (es) |
JP (1) | JP2017522312A (es) |
KR (1) | KR20170032373A (es) |
AU (1) | AU2015289773A1 (es) |
CA (1) | CA2955015A1 (es) |
MX (1) | MX2017000630A (es) |
WO (1) | WO2016011083A1 (es) |
Families Citing this family (23)
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MA43552A (fr) | 2016-04-15 | 2018-11-07 | Alpine Immune Sciences Inc | Protéines immunomodulatrices à variants de cd80 et leurs utilisations |
MX2018012472A (es) | 2016-04-15 | 2019-08-12 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras variantes de ligando icos y sus usos. |
CA3032120A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd155 variant immunomodulatory proteins and uses thereof |
US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
WO2018022945A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd112 variant immunomodulatory proteins and uses thereof |
WO2018148180A2 (en) * | 2017-02-07 | 2018-08-16 | Immune Design Corp. | Materials and methods for identifying and treating cancer patients |
JP2020511144A (ja) | 2017-03-16 | 2020-04-16 | アルパイン イミューン サイエンシズ インコーポレイテッド | Pd−l2バリアント免疫調節タンパク質及びその使用 |
NZ756395A (en) | 2017-03-16 | 2024-01-26 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
FI3596116T3 (fi) | 2017-03-16 | 2023-11-09 | Alpine Immune Sciences Inc | Immunomodulatorisia pd-l1-varianttiproteiineja ja niiden käyttöjä |
MA50360A (fr) | 2017-10-10 | 2020-08-19 | Alpine Immune Sciences Inc | Protéines immunomodulatrices de variants de ctla-4 et leurs utilisations |
KR20200085777A (ko) | 2017-10-18 | 2020-07-15 | 알파인 이뮨 사이언시즈, 인코포레이티드 | 변이체 icos 리간드 면역조절 단백질 및 관련 조성물 및 방법 |
AU2019205273B2 (en) | 2018-01-03 | 2024-04-04 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
US20210046130A1 (en) * | 2018-01-24 | 2021-02-18 | Virogin Biotech Canada Ltd | Recombinant viral vaccines |
WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
JP2022500034A (ja) * | 2018-09-10 | 2022-01-04 | トルク セラピューティクス, インコーポレイテッド | 抗原特異的tリンパ球ならびに抗原特異的tリンパ球を作製および使用する方法 |
CN113544144A (zh) | 2018-09-19 | 2021-10-22 | 高山免疫科学股份有限公司 | 变体cd80融合蛋白和相关构建体的方法和用途 |
EP3628735A1 (en) | 2018-09-25 | 2020-04-01 | Centre National De La Recherche Scientifique | Antisense rna targeting pmp22 for the treatment of charcot-marie-tooth 1a disease |
AU2019389151A1 (en) | 2018-11-30 | 2021-06-10 | Alpine Immune Sciences, Inc. | CD86 variant immunomodulatory proteins and uses thereof |
JP2022529059A (ja) | 2019-04-17 | 2022-06-16 | アルパイン イミューン サイエンシズ インコーポレイテッド | バリアントicosリガンド(icosl)融合タンパク質の方法および使用 |
CN116903727A (zh) | 2020-05-08 | 2023-10-20 | 高山免疫科学股份有限公司 | 具有和不具有t细胞抑制蛋白的april和baff抑制性免疫调节蛋白及其使用方法 |
KR20240019124A (ko) | 2021-05-07 | 2024-02-14 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Taci-fc 융합 면역조절 단백질의 투여 및 치료 방법 |
WO2023172883A1 (en) | 2022-03-07 | 2023-09-14 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses |
WO2024077018A2 (en) | 2022-10-04 | 2024-04-11 | Alpine Immune Sciences, Inc. | Methods and uses of taci-fc fusion immunomodulatory protein |
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-
2015
- 2015-07-14 CA CA2955015A patent/CA2955015A1/en not_active Abandoned
- 2015-07-14 MX MX2017000630A patent/MX2017000630A/es unknown
- 2015-07-14 WO PCT/US2015/040453 patent/WO2016011083A1/en active Application Filing
- 2015-07-14 AU AU2015289773A patent/AU2015289773A1/en not_active Abandoned
- 2015-07-14 EP EP15745647.6A patent/EP3169352A1/en not_active Withdrawn
- 2015-07-14 JP JP2017502194A patent/JP2017522312A/ja active Pending
- 2015-07-14 US US15/326,052 patent/US20170196954A1/en not_active Abandoned
- 2015-07-14 KR KR1020177003844A patent/KR20170032373A/ko unknown
Also Published As
Publication number | Publication date |
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JP2017522312A (ja) | 2017-08-10 |
AU2015289773A1 (en) | 2017-02-02 |
WO2016011083A1 (en) | 2016-01-21 |
US20170196954A1 (en) | 2017-07-13 |
EP3169352A1 (en) | 2017-05-24 |
CA2955015A1 (en) | 2016-01-21 |
KR20170032373A (ko) | 2017-03-22 |
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