MX2016013216A - Dispositivos mejorados para la separacion de materiales biologicos. - Google Patents

Dispositivos mejorados para la separacion de materiales biologicos.

Info

Publication number
MX2016013216A
MX2016013216A MX2016013216A MX2016013216A MX2016013216A MX 2016013216 A MX2016013216 A MX 2016013216A MX 2016013216 A MX2016013216 A MX 2016013216A MX 2016013216 A MX2016013216 A MX 2016013216A MX 2016013216 A MX2016013216 A MX 2016013216A
Authority
MX
Mexico
Prior art keywords
separation
biological materials
improved devices
devices
systems
Prior art date
Application number
MX2016013216A
Other languages
English (en)
Inventor
CHARLOT David
Pablo Hinestrosa Salazar Juan
Yang Kai
Swanson Paul
Krishnan Rajaram
V Dobrovolskaya Irina
Original Assignee
Biological dynamics inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biological dynamics inc filed Critical Biological dynamics inc
Publication of MX2016013216A publication Critical patent/MX2016013216A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Sampling And Sample Adjustment (AREA)
  • External Artificial Organs (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención incluye métodos, dispositivos y sistemas para el aislamiento de nanopartículas, que incluyen ácidos nucleicos, de muestras biológicas. En diversos aspectos, los métodos, dispositivos y sistemas pueden permitir un procedimiento rápido que requiere una cantidad mínima de material y/o resulta en aislamiento de alta pureza de componentes biológicos de fluidos complejos tales como sangre o muestras ambientales.
MX2016013216A 2014-04-08 2015-04-07 Dispositivos mejorados para la separacion de materiales biologicos. MX2016013216A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461977006P 2014-04-08 2014-04-08
US201461977249P 2014-04-09 2014-04-09
PCT/US2015/024624 WO2015157217A1 (en) 2014-04-08 2015-04-07 Improved devices for separation of biological materials

Publications (1)

Publication Number Publication Date
MX2016013216A true MX2016013216A (es) 2017-05-01

Family

ID=54208908

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016013216A MX2016013216A (es) 2014-04-08 2015-04-07 Dispositivos mejorados para la separacion de materiales biologicos.

Country Status (9)

Country Link
US (2) US9387489B2 (es)
EP (1) EP3129481A4 (es)
JP (1) JP2017512483A (es)
KR (1) KR20160144428A (es)
CN (1) CN106459966A (es)
CA (1) CA2945146A1 (es)
IL (1) IL248200A0 (es)
MX (1) MX2016013216A (es)
WO (1) WO2015157217A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11198126B2 (en) 2011-10-31 2021-12-14 Fluid-Screen, Inc. Apparatus for pathogen detection
US8932815B2 (en) 2012-04-16 2015-01-13 Biological Dynamics, Inc. Nucleic acid sample preparation
WO2015196141A1 (en) * 2014-06-20 2015-12-23 Biological Dynamics, Inc. Nucleic acid sample preparation
KR20150014925A (ko) 2012-04-16 2015-02-09 바이오로지컬 다이나믹스, 인크. 핵산 시료 제조
CA2945146A1 (en) 2014-04-08 2015-10-15 Biological Dynamics, Inc. Improved devices for separation of biological materials
KR101701618B1 (ko) * 2015-06-23 2017-02-13 국립암센터 전도성 고분자를 이용한 세포 유리 ｄｎａ 검출용 구조체 및 이의 용도
AU2017237187B2 (en) 2016-03-24 2022-12-08 Biological Dynamics, Inc. Disposable fluidic cartridge and components
SG11201808959QA (en) * 2016-04-15 2018-11-29 Fluid Screen Inc Analyte detection methods and apparatus using dielectrophoresis and electroosmosis
US9873129B1 (en) * 2016-12-19 2018-01-23 Charlot Biosciences, Inc. Multi-planar microelectrode array device and methods of making and using same
US10818379B2 (en) 2017-05-08 2020-10-27 Biological Dynamics, Inc. Methods and systems for analyte information processing
CN112041067A (zh) 2017-12-19 2020-12-04 生物动力学公司 用于从生物样品中检测多种分析物的方法和装置
WO2019195196A1 (en) * 2018-04-02 2019-10-10 Biological Dynamics, Inc. Dielectric materials
EP4058778A4 (en) 2019-11-13 2023-12-27 Fluid-Screen, Inc. METHOD AND DEVICE FOR DETECTING BACTERIA IN A SAMPLE USING DIELECTROPHORESIS
US11072810B2 (en) 2019-11-13 2021-07-27 Fluid-Screen, Inc. Apparatus and methods to rapidly detect, separate, purify, and quantify various viruses from cells, cultured medium and other fluids

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6149789A (en) 1990-10-31 2000-11-21 Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Process for manipulating microscopic, dielectric particles and a device therefor
US5632957A (en) 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US6071394A (en) 1996-09-06 2000-06-06 Nanogen, Inc. Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis
US6403367B1 (en) 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US6641708B1 (en) 1996-01-31 2003-11-04 Board Of Regents, The University Of Texas System Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation
GB9615775D0 (en) 1996-07-26 1996-09-04 British Tech Group Apparatus and method for characterising particles using dielectrophoresis
EP1089824B1 (de) 1998-06-26 2003-11-05 Evotec OAI AG Elektrodenanordnung zur dielektrophoretischen partikelablenkung
US6203683B1 (en) 1998-11-09 2001-03-20 Princeton University Electrodynamically focused thermal cycling device
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
CN1181337C (zh) 2000-08-08 2004-12-22 清华大学 微流体***中实体分子的操纵方法及相关试剂盒
US6824664B1 (en) 1999-11-04 2004-11-30 Princeton University Electrode-less dielectrophorises for polarizable particles
DE60113287D1 (de) 2000-06-14 2005-10-13 Univ Texas Systeme und verfahren zur zellteilbevölkerungsanalyse
CN100392384C (zh) 2000-10-09 2008-06-04 清华大学 芯片上分离实体分子的方法和样品溶液
US7014744B2 (en) * 2001-08-24 2006-03-21 Applera Corporation Method of purification and concentration using AC fields with a transfer tip
AU2002364177A1 (en) * 2001-12-18 2003-06-30 Massachusetts Institute Of Technology Microfluidic pumps and mixers driven by induced-charge electro-osmosis
US6887362B2 (en) 2002-02-06 2005-05-03 Nanogen, Inc. Dielectrophoretic separation and immunoassay methods on active electronic matrix devices
GB2392977A (en) 2002-09-13 2004-03-17 Suisse Electronique Microtech A fluidic dielectrophoretic system and method for analysing biomolecules
EP1583956A4 (en) 2002-12-20 2009-07-15 Univ Texas METHOD AND DEVICE FOR ELECTRIC CUTTING ANALYSIS
DE10311716A1 (de) 2003-03-17 2004-10-14 Evotec Oai Ag Verfahren und Vorrichtung zur Trennung von Partikeln in einer Flüssigkeitsströmung
WO2005012872A2 (en) 2003-07-25 2005-02-10 Platypus Technologies, Llc Liquid crystal based analyte detection
EP1721014B1 (en) 2004-02-18 2013-07-17 Trustees Of Boston University Method for detecting and quantifying rare mutations/polymorphisms
JPWO2005121767A1 (ja) 2004-05-25 2008-04-10 有限会社フルイド マイクロ流体デバイス及びこれを用いる分析分取装置
ITBO20040420A1 (it) * 2004-07-07 2004-10-07 Type S R L Macchina per taglio e formatura di piattine metalliche
JP2006047153A (ja) 2004-08-05 2006-02-16 Sony Corp Ｄｎａチップの製造方法と製造システム、ハイブリダイゼーション検出方法と検出システム、並びに基板処理装置と基板処理方法
JP4645110B2 (ja) 2004-09-15 2011-03-09 ソニー株式会社 誘電泳動を利用するハイブリダイゼーション検出部と該検出部を備えるセンサーチップ、並びにハイブリダイゼーション検出方法
EP1764418B1 (en) 2005-09-14 2012-08-22 STMicroelectronics Srl Method and device for the treatment of biological samples using dielectrophoresis
US20070080062A1 (en) * 2005-10-03 2007-04-12 Harnett Cindy K Coated metal structures and methods of making and using thereof
WO2007102839A2 (en) 2005-10-27 2007-09-13 Applera Corporation Optoelectronic separation of biomolecules
TWI304752B (en) 2005-12-09 2009-01-01 Ind Tech Res Inst Multi-sample microfluidic dielectrophoresis separator
KR100745754B1 (ko) * 2005-12-29 2007-08-02 삼성전자주식회사 금속 기둥 전극 구조를 포함하는 유전 영동을 이용하여입자를 조작하기 위한 장치 및 그를 이용하여 빠른유속으로 유전 영동에 의하여 입자를 조작할 수 있는 방법
DE102006002462A1 (de) * 2006-01-18 2007-07-19 Evotec Technologies Gmbh Elektrischer Feldkäfig und zugehöriges Betriebsverfahren
US20100163414A1 (en) 2006-03-21 2010-07-01 Koninklijke Philips Electronics N.V. Microelectronic device with field electrodes
WO2007116406A1 (en) * 2006-04-10 2007-10-18 Technion Research & Development Foundation Ltd. Method and device for electrokinetic manipulation
ITTO20060273A1 (it) * 2006-04-12 2007-10-13 Silicon Biosystem S P A Metodi ed apparati per la selezione e/o il processamento di particellle, in particolare per la lisi selettiva e/o ottimizzata di cellule
KR100813254B1 (ko) 2006-05-29 2008-03-13 삼성전자주식회사 유전 영동을 통하여 분극성 분석물을 분리하기 위한 장치및 그를 이용하여 시료 중의 분극성 물질을 분리하는 방법
JP2008298575A (ja) 2007-05-31 2008-12-11 Panasonic Corp 電極および製造方法とそれを用いた検出装置と検出方法
WO2009146143A2 (en) 2008-04-03 2009-12-03 The Regents Of The University Of California Ex-vivo multi-dimensional system for the separation and isolation of cells, vesicles, nanoparticles and biomarkers
JP5306092B2 (ja) * 2009-07-17 2013-10-02 キヤノン株式会社 流体制御装置
DE102009028493B4 (de) * 2009-08-13 2023-08-24 Robert Bosch Gmbh Mikrofluidische Zelle
WO2011057347A1 (en) 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
GB201102385D0 (en) * 2011-02-10 2011-03-30 Biocule Scotland Ltd Two-dimensional gel electrophoresis apparatus and method
CN102320559B (zh) * 2011-09-14 2014-06-18 上海交通大学 一种中空结构的微阵列电极的制备方法
KR20150014925A (ko) 2012-04-16 2015-02-09 바이오로지컬 다이나믹스, 인크. 핵산 시료 제조
US8932815B2 (en) 2012-04-16 2015-01-13 Biological Dynamics, Inc. Nucleic acid sample preparation
WO2015196141A1 (en) 2014-06-20 2015-12-23 Biological Dynamics, Inc. Nucleic acid sample preparation
WO2014015187A1 (en) 2012-07-18 2014-01-23 Biological Dynamics, Inc. Manipulation of microparticles in low field dielectrophoretic regions
WO2014028222A1 (en) 2012-07-31 2014-02-20 Crown Bioscience, Inc. Biomarkers for identifying esophageal cancer patients for treatment with an anti-egfr drug
US20140066317A1 (en) 2012-09-04 2014-03-06 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US9551665B2 (en) 2012-10-01 2017-01-24 National Cheng Kung University Method for detecting mitochondria gene alterations
WO2015038797A1 (en) 2013-09-13 2015-03-19 The Board Of Trustees Of The Leland Stanford Junior University Plasmonic beads for multiplexed analysis by flow detection systems
CA2945146A1 (en) * 2014-04-08 2015-10-15 Biological Dynamics, Inc. Improved devices for separation of biological materials
US20160327549A1 (en) 2015-05-04 2016-11-10 Biological Dynamics, Inc. Particle based immunoassay with alternating current electrokinetics

Also Published As

Publication number Publication date
EP3129481A1 (en) 2017-02-15
US9387489B2 (en) 2016-07-12
JP2017512483A (ja) 2017-05-25
EP3129481A4 (en) 2017-10-25
CA2945146A1 (en) 2015-10-15
KR20160144428A (ko) 2016-12-16
WO2015157217A1 (en) 2015-10-15
IL248200A0 (en) 2016-11-30
US20160271622A1 (en) 2016-09-22
US20150283553A1 (en) 2015-10-08
CN106459966A (zh) 2017-02-22
US9682385B2 (en) 2017-06-20

Similar Documents

Publication Publication Date Title
MX2016013216A (es) Dispositivos mejorados para la separacion de materiales biologicos.
MX2018006430A (es) Preparacion de muestras de acido nucleico.
PH12017500861A1 (en) Anti-interleukin-33 antibodies and uses thereof
EP3429752A4 (en) SYSTEMS AND METHODS FOR PERFORMING BIOLOGICAL TESTS
EP3430372A4 (en) DEVICES AND METHODS FOR PREPARING AND DELIVERING BIOLOGICAL TEST SAMPLE
EP3386391A4 (en) Specimen container and method for separating serum or plasma from whole blood
MY188940A (en) Anti-pd-l1 antibodies and diagnostic uses thereof
MX2016013156A (es) Dispositivos, sistemas y metodos fluidicos, para encapsular y dividir reactivos, y aplicaciones de los mismos.
EP3234200A4 (en) Compositions and methods for targeted depletion, enrichment, and partitioning of nucleic acids using crispr/cas system proteins
MX2019007742A (es) Metodos para aislar microvesiculas.
IL269155B (en) Systems and methods for automatic preparation of biological samples
EP3149464A4 (en) System and method for electronic biological sample analysis
EP3207163A4 (en) Apparatuses, methods and systems for automated processing of nucleic acids and electrophoretic sample preparation
EP3194343A4 (en) Process and apparatus for separating valuable or harmful liquids from slurries
WO2015196141A8 (en) Nucleic acid sample preparation
PT3634125T (pt) Sistema e método para o transporte controlado de amostras biológicas
EP3254067A4 (en) Systems and methods for detection and analysis of biological species
EP3464348A4 (en) METHODS OF PRODUCING ACTIVE ANTIBODIES FROM BIOLOGICAL FLUIDS
EP3452197A4 (en) FAST EXTRACTION OF NUCLEIC ACIDS FROM CLINICAL SAMPLES FOR DOWNSTREAM APPLICATIONS
MX2016016233A (es) Anticuerpos anti-lgr5 y sus usos.
EP3631414A4 (en) ASSAY SYSTEMS AND METHODS FOR PROCESSING SAMPLE ENTITIES
EP3250919A4 (en) METHOD AND DEVICE FOR QUANTIZING BLOOD SAMPLES
WO2016055647A3 (fr) Procede de preparation de plasma universel
EP3122903A4 (en) System and method for processing biological samples
GB201402347D0 (en) Fixative solution for materials or samples of biological origin