MX2015017485A - Uso de moleculas inhibidoras de semaforina-4d en combinacion con una terapia de modulacion inmune para inhibir crecimiento tumoral y metastasis. - Google Patents

Uso de moleculas inhibidoras de semaforina-4d en combinacion con una terapia de modulacion inmune para inhibir crecimiento tumoral y metastasis.

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Publication number
MX2015017485A
MX2015017485A MX2015017485A MX2015017485A MX2015017485A MX 2015017485 A MX2015017485 A MX 2015017485A MX 2015017485 A MX2015017485 A MX 2015017485A MX 2015017485 A MX2015017485 A MX 2015017485A MX 2015017485 A MX2015017485 A MX 2015017485A
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Mexico
Prior art keywords
semaphorin
metastases
combination
tumor growth
immune modulating
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Application number
MX2015017485A
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English (en)
Inventor
Ernest S Smith
Elizabeth E Evans
Maurice Zauderer
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Vaccinex Inc
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Publication date
Application filed by Vaccinex Inc filed Critical Vaccinex Inc
Publication of MX2015017485A publication Critical patent/MX2015017485A/es

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Abstract

En la presente se proporcionan métodos para inhibir, retrasar o reducir crecimiento de tumor y metástasis de células cancerosas que expresan plexina-B1 en un sujeto, que comprenden administrar al sujeto una cantidad eficaz de una molécula de unión aislada que se une específicamente a semaforina-4D (SEMA4D) en combinación con una cantidad eficaz de al menos otra terapia de modulación inmune.
MX2015017485A 2013-06-25 2014-06-20 Uso de moleculas inhibidoras de semaforina-4d en combinacion con una terapia de modulacion inmune para inhibir crecimiento tumoral y metastasis. MX2015017485A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361839170P 2013-06-25 2013-06-25
US201361874241P 2013-09-05 2013-09-05
US201361884771P 2013-09-30 2013-09-30
US201361907845P 2013-11-22 2013-11-22
PCT/US2014/043466 WO2014209802A1 (en) 2013-06-25 2014-06-20 Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases

Publications (1)

Publication Number Publication Date
MX2015017485A true MX2015017485A (es) 2016-03-31

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MX2015017485A MX2015017485A (es) 2013-06-25 2014-06-20 Uso de moleculas inhibidoras de semaforina-4d en combinacion con una terapia de modulacion inmune para inhibir crecimiento tumoral y metastasis.

Country Status (18)

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US (5) US9828435B2 (es)
EP (2) EP3013350B1 (es)
JP (3) JP6611709B2 (es)
KR (2) KR102291971B1 (es)
CN (1) CN105492016A (es)
AU (2) AU2014302812B2 (es)
BR (1) BR112015032690B1 (es)
CA (2) CA2916245C (es)
DK (1) DK3013350T3 (es)
EA (1) EA036591B1 (es)
ES (1) ES2782834T3 (es)
IL (1) IL243301B (es)
MX (1) MX2015017485A (es)
NZ (1) NZ631015A (es)
PL (1) PL3013350T3 (es)
PT (1) PT3013350T (es)
SG (2) SG10201902380SA (es)
WO (1) WO2014209802A1 (es)

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