MX2015015746A - Proceso para la preparacion de arformoterol o sal del mismo. - Google Patents

Proceso para la preparacion de arformoterol o sal del mismo.

Info

Publication number
MX2015015746A
MX2015015746A MX2015015746A MX2015015746A MX2015015746A MX 2015015746 A MX2015015746 A MX 2015015746A MX 2015015746 A MX2015015746 A MX 2015015746A MX 2015015746 A MX2015015746 A MX 2015015746A MX 2015015746 A MX2015015746 A MX 2015015746A
Authority
MX
Mexico
Prior art keywords
arformoterol
preparation
salt
tartrate
improved process
Prior art date
Application number
MX2015015746A
Other languages
English (en)
Inventor
Shekhar Bhaskar Bhirud
Suresh Mahadev Kadam
Sachin Baban Gavhane
Shailesh Shrirang Pawase
Aniket Ashokrao Deshpande
Anil Subhash Bhujbal
Original Assignee
Glenmark Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Ltd filed Critical Glenmark Pharmaceuticals Ltd
Publication of MX2015015746A publication Critical patent/MX2015015746A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se relaciona con un proceso mejorado para la preparación de L-(+)-tartrato de artormoterol. Más específicamente, la presente invención se relaciona con un proceso novedoso para la preparación de L-(+)-tartrato de arformoterol mediante D-(-)-tartrato de arformoterol.
MX2015015746A 2013-05-17 2014-05-15 Proceso para la preparacion de arformoterol o sal del mismo. MX2015015746A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1762MU2013 2013-05-17
PCT/IB2014/061444 WO2014184756A2 (en) 2013-05-17 2014-05-15 Process for the preparation of arformoterol or salt thereof

Publications (1)

Publication Number Publication Date
MX2015015746A true MX2015015746A (es) 2016-03-09

Family

ID=51898937

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015015746A MX2015015746A (es) 2013-05-17 2014-05-15 Proceso para la preparacion de arformoterol o sal del mismo.

Country Status (7)

Country Link
US (1) US9499475B2 (es)
EP (1) EP2997009A4 (es)
JP (1) JP2016523832A (es)
CN (1) CN105431409A (es)
MX (1) MX2015015746A (es)
RU (1) RU2015147242A (es)
WO (1) WO2014184756A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111909049B (zh) * 2020-09-03 2023-04-25 扬州中宝药业股份有限公司 一种酒石酸阿福特罗精制的方法
CN114456078B (zh) * 2022-01-19 2022-09-16 汉瑞药业(荆门)有限公司 一种(r)-n-苄基-1-(4-甲氧基苯基)丙-2-胺的制备方法
CN114544809B (zh) * 2022-02-16 2022-12-09 汉瑞药业(荆门)有限公司 一种阿福特罗中间体及其对映异构体手性纯度的hplc检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040344A (en) 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
US6472563B1 (en) * 2001-11-09 2002-10-29 Sepracor Inc. Formoterol tartrate process and polymorph
WO2009106997A2 (en) * 2008-02-28 2009-09-03 Actavis Group Ptc Ehf Amorphous arformoterol l-(+)-tartrate
US20120053246A1 (en) * 2010-08-26 2012-03-01 Actavis Group Ptc Ehf Purification process for preparing highly pure arformoterol tartrate substantially free of desformyl impurity
EP2825525B1 (en) * 2012-03-12 2018-04-25 Laboratorios Lesvi S.L. New polymorphic form of a long-acting beta-2 adrenoceptor agonist

Also Published As

Publication number Publication date
RU2015147242A (ru) 2017-06-22
JP2016523832A (ja) 2016-08-12
WO2014184756A3 (en) 2015-01-15
US20160083334A1 (en) 2016-03-24
WO2014184756A2 (en) 2014-11-20
US9499475B2 (en) 2016-11-22
EP2997009A4 (en) 2017-01-18
CN105431409A (zh) 2016-03-23
EP2997009A2 (en) 2016-03-23

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