MX2015014568A - Composiciones y metodos para tratar y prevenir la degeneracion macular. - Google Patents
Composiciones y metodos para tratar y prevenir la degeneracion macular.Info
- Publication number
- MX2015014568A MX2015014568A MX2015014568A MX2015014568A MX2015014568A MX 2015014568 A MX2015014568 A MX 2015014568A MX 2015014568 A MX2015014568 A MX 2015014568A MX 2015014568 A MX2015014568 A MX 2015014568A MX 2015014568 A MX2015014568 A MX 2015014568A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compositions
- macular degeneration
- treating
- preventing macular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Se describen composiciones y métodos para tratar la degeneración macular. Los métodos usan inhibidores de IL17, tales como receptores de lL17, así como proteínas de fusión que incluyen un receptor de lL17 fusionado con un dominio de multimerización, y vectores víricos recombinantes que codifican dichas fusiones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361813014P | 2013-04-17 | 2013-04-17 | |
PCT/US2014/034538 WO2014172560A1 (en) | 2013-04-17 | 2014-04-17 | Compositions and methods for treating and preventing macular degeneration |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015014568A true MX2015014568A (es) | 2016-12-02 |
Family
ID=50942311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015014568A MX2015014568A (es) | 2013-04-17 | 2014-04-17 | Composiciones y metodos para tratar y prevenir la degeneracion macular. |
Country Status (8)
Country | Link |
---|---|
US (2) | US10640771B2 (es) |
EP (2) | EP3741385A1 (es) |
CN (2) | CN115715797A (es) |
AU (1) | AU2014253919B2 (es) |
CA (2) | CA2909706C (es) |
MX (1) | MX2015014568A (es) |
SG (3) | SG10201708547YA (es) |
WO (1) | WO2014172560A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140044731A1 (en) * | 2011-01-04 | 2014-02-13 | Robert Nussenblatt | Methods of treating age-related macular degeneration |
CN106163573A (zh) * | 2014-02-06 | 2016-11-23 | 建新公司 | 用于治疗和预防黄斑变性的组合物及方法 |
GB201519086D0 (en) * | 2015-10-28 | 2015-12-09 | Syncona Partners Llp | Gene Therapy |
CA3073137A1 (en) | 2016-08-19 | 2018-02-22 | Jeffrey S. Bartlett | Methods and compositions for treating conditions using recombinant self-complementary adeno-associated virus |
US20200318080A1 (en) * | 2016-08-19 | 2020-10-08 | Colorado State University Research Foundation | Methods and compositions for treating equine conditions using recombinant self-complementary adeno-associated virus |
KR20190088561A (ko) | 2016-12-07 | 2019-07-26 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 인터류킨-1 수용체 길항제(IL-1RA) cDNA |
WO2021026294A1 (en) * | 2019-08-06 | 2021-02-11 | Children's Medical Center Corporation | Methods and compositions for reconstituting microglia |
CA3238451A1 (en) * | 2021-11-19 | 2023-05-25 | Ying Kai CHAN | Materials and methods for treatment of macular degeneration |
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US4657760A (en) | 1979-03-20 | 1987-04-14 | Ortho Pharmaceutical Corporation | Methods and compositions using monoclonal antibody to human T cells |
US5206344A (en) | 1985-06-26 | 1993-04-27 | Cetus Oncology Corporation | Interleukin-2 muteins and polymer conjugation thereof |
US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
DE10399032I1 (de) | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US6673776B1 (en) | 1989-03-21 | 2004-01-06 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human |
US6214804B1 (en) | 1989-03-21 | 2001-04-10 | Vical Incorporated | Induction of a protective immune response in a mammal by injecting a DNA sequence |
US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
US5225212A (en) | 1989-10-20 | 1993-07-06 | Liposome Technology, Inc. | Microreservoir liposome composition and method |
FR2658432B1 (fr) | 1990-02-22 | 1994-07-01 | Medgenix Group Sa | Microspheres pour la liberation controlee des substances hydrosolubles et procede de preparation. |
AU8200191A (en) | 1990-07-09 | 1992-02-04 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | High efficiency packaging of mutant adeno-associated virus using amber suppressions |
MY109299A (en) | 1990-08-15 | 1996-12-31 | Virogenetics Corp | Recombinant pox virus encoding flaviviral structural proteins |
US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
JP3534749B2 (ja) | 1991-08-20 | 2004-06-07 | アメリカ合衆国 | アデノウイルスが介在する胃腸管への遺伝子の輸送 |
US5834441A (en) | 1993-09-13 | 1998-11-10 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Adeno-associated viral (AAV) liposomes and methods related thereto |
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US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
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ATE278794T1 (de) | 1995-06-15 | 2004-10-15 | Crucell Holland Bv | Verpackungssysteme für humane, menschliche adenoviren, zur verwendung in die gentherapie |
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JP2003505020A (ja) | 1999-07-02 | 2003-02-12 | ジェネンテック・インコーポレーテッド | ペプチドリガンドドメイン及び多量体化ドメインを含む融合ペプチド |
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-
2014
- 2014-04-17 US US14/785,159 patent/US10640771B2/en active Active
- 2014-04-17 AU AU2014253919A patent/AU2014253919B2/en active Active
- 2014-04-17 CN CN202211294302.5A patent/CN115715797A/zh active Pending
- 2014-04-17 CA CA2909706A patent/CA2909706C/en active Active
- 2014-04-17 CN CN201480034291.4A patent/CN105682674A/zh active Pending
- 2014-04-17 CA CA3182572A patent/CA3182572A1/en active Pending
- 2014-04-17 SG SG10201708547YA patent/SG10201708547YA/en unknown
- 2014-04-17 EP EP20181596.6A patent/EP3741385A1/en active Pending
- 2014-04-17 EP EP14729998.6A patent/EP2986310B1/en active Active
- 2014-04-17 MX MX2015014568A patent/MX2015014568A/es active IP Right Grant
- 2014-04-17 SG SG10201912901YA patent/SG10201912901YA/en unknown
- 2014-04-17 WO PCT/US2014/034538 patent/WO2014172560A1/en active Application Filing
- 2014-04-17 SG SG11201508297YA patent/SG11201508297YA/en unknown
-
2020
- 2020-03-31 US US16/835,913 patent/US20210040484A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN105682674A (zh) | 2016-06-15 |
CA2909706C (en) | 2023-02-14 |
AU2014253919B2 (en) | 2019-06-20 |
SG10201912901YA (en) | 2020-02-27 |
CN115715797A (zh) | 2023-02-28 |
WO2014172560A1 (en) | 2014-10-23 |
EP2986310A1 (en) | 2016-02-24 |
US10640771B2 (en) | 2020-05-05 |
EP3741385A1 (en) | 2020-11-25 |
EP2986310B1 (en) | 2020-08-05 |
AU2014253919A1 (en) | 2015-11-12 |
SG11201508297YA (en) | 2015-11-27 |
CA2909706A1 (en) | 2014-10-23 |
SG10201708547YA (en) | 2017-11-29 |
US20160068844A1 (en) | 2016-03-10 |
CA3182572A1 (en) | 2014-10-23 |
US20210040484A1 (en) | 2021-02-11 |
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