MX2015000668A - Procedimiento de preparacion de 5-fluoro-1h-pirazoles. - Google Patents

Procedimiento de preparacion de 5-fluoro-1h-pirazoles.

Info

Publication number
MX2015000668A
MX2015000668A MX2015000668A MX2015000668A MX2015000668A MX 2015000668 A MX2015000668 A MX 2015000668A MX 2015000668 A MX2015000668 A MX 2015000668A MX 2015000668 A MX2015000668 A MX 2015000668A MX 2015000668 A MX2015000668 A MX 2015000668A
Authority
MX
Mexico
Prior art keywords
pyrazoles
fluoro
preparation
iii
general formula
Prior art date
Application number
MX2015000668A
Other languages
English (en)
Other versions
MX360114B (es
Inventor
Sergii Pazenok
Norbert Lui
Vadim Mikhailovich Timoshenko
Elena Ivanovna Kaminskaya
Yuriy Grigorievich Shermo-Lovich
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2015000668A publication Critical patent/MX2015000668A/es
Publication of MX360114B publication Critical patent/MX360114B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se describe un nuevo procedimiento de preparación de 5-fluoro-1H-pirazoles de fórmula general (I) (ver Fórmula) resultantes de la reacción de una olefina de fórmula general (II) (ver Fórmula) con hidrazinas de fórmula (III) R1-NH-NH2 (III), en la que R1 es seleccionado entre alquilo C1-C6, arilo C5-C10 R2 es un resto trihalometilo con al menos un átomo de flúor; y R3 es seleccionado entre haloalquilo C1-C5, CF3, C2F5, C3F7, CF2CF2CI, CFCICF3, en presencia de agua y una base.
MX2015000668A 2012-07-19 2013-07-17 Procedimiento de preparacion de 5-fluoro-1h-pirazoles. MX360114B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12177058 2012-07-19
PCT/EP2013/065094 WO2014012975A1 (en) 2012-07-19 2013-07-17 Process for the preparation of 5-fluoro-1h-pyrazoles

Publications (2)

Publication Number Publication Date
MX2015000668A true MX2015000668A (es) 2015-04-08
MX360114B MX360114B (es) 2018-10-23

Family

ID=48803540

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015000668A MX360114B (es) 2012-07-19 2013-07-17 Procedimiento de preparacion de 5-fluoro-1h-pirazoles.

Country Status (17)

Country Link
US (1) US9302994B2 (es)
EP (1) EP2885277B1 (es)
JP (1) JP6148730B2 (es)
KR (1) KR102044202B1 (es)
CN (1) CN104470900B (es)
BR (1) BR112015000987B1 (es)
DK (1) DK2885277T3 (es)
ES (1) ES2605382T3 (es)
HR (1) HRP20161563T1 (es)
HU (1) HUE029803T2 (es)
IL (1) IL236450A (es)
MX (1) MX360114B (es)
PL (1) PL2885277T3 (es)
PT (1) PT2885277T (es)
SI (1) SI2885277T1 (es)
TW (1) TWI609856B (es)
WO (1) WO2014012975A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016011890B1 (pt) * 2013-11-27 2021-11-16 Bayer Animal Health Gmbh Processo para preparação de 5-fluoro-1h-pirazóis
TWI694066B (zh) * 2014-05-27 2020-05-21 德商拜耳動物保健有限公司 始於六氟丙烯之製備５-氟-１ｈ-吡唑的方法
ES2750353T3 (es) * 2014-08-19 2020-03-25 Bayer Animal Health Gmbh Procedimiento de preparación de 5-fluoro-1H-pirazoles partiendo de hexafluoropropeno
CN114698369A (zh) 2019-08-14 2022-07-01 威隆股份公司 用于防治寄生虫的包含替戈拉纳的组合物
CA3178621A1 (en) 2020-05-27 2021-12-02 Franz-Josef Mais Method for preparing 2-chloro-n-(1-cyanocyclopropyl)-5-[2'-methyl-5'-(pentafluoroethyl)-4'-(trifluoromethyl)-2'h-1,3'-bipyrazol-4-yl]benzamide
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1456419A1 (ru) 1987-06-18 1989-02-07 Институт элементоорганических соединений им.А.Н.Несмеянова Способ получени 1-замещенных 3-пентафторэтил-4-трифторметил-5-фторпиразолов
JP2817863B2 (ja) * 1992-02-21 1998-10-30 宇部興産株式会社 含フッ素ピラゾール化合物、その製法及び有害生物防除剤
US5254774A (en) 1992-12-28 1993-10-19 Minnesota Mining And Manufacturing Company Preparation of hexafluoropropene oligomers
EP1854788B8 (en) * 2005-02-25 2012-12-26 Sagami Chemical Research Institute Method for producing 1-substituted-3-fluoroalkyl pyrazole-4-carboxylate
UA99460C2 (ru) * 2007-06-01 2012-08-27 Басф Се Способ получения n-замещенных (3-дигалометил-1-метилпиразол-4-ил)карбоксамидов
EP2184273A1 (de) * 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
WO2015078847A1 (en) * 2013-11-27 2015-06-04 Bayer Cropscience Ag Process for the preparation of 5-fluoro-1h-pyrazoles
BR112016011890B1 (pt) * 2013-11-27 2021-11-16 Bayer Animal Health Gmbh Processo para preparação de 5-fluoro-1h-pirazóis

Also Published As

Publication number Publication date
DK2885277T3 (en) 2016-12-12
JP2015522599A (ja) 2015-08-06
KR102044202B1 (ko) 2019-11-13
SI2885277T1 (sl) 2016-12-30
US9302994B2 (en) 2016-04-05
ES2605382T3 (es) 2017-03-14
EP2885277B1 (en) 2016-09-07
TW201408647A (zh) 2014-03-01
PL2885277T3 (pl) 2017-03-31
US20150152062A1 (en) 2015-06-04
CN104470900A (zh) 2015-03-25
JP6148730B2 (ja) 2017-06-14
MX360114B (es) 2018-10-23
TWI609856B (zh) 2018-01-01
BR112015000987A2 (pt) 2017-06-27
CN104470900B (zh) 2016-10-19
EP2885277A1 (en) 2015-06-24
BR112015000987B1 (pt) 2020-05-26
WO2014012975A1 (en) 2014-01-23
PT2885277T (pt) 2016-12-12
IL236450A (en) 2016-08-31
HRP20161563T1 (hr) 2016-12-30
IL236450A0 (en) 2015-02-26
HUE029803T2 (en) 2017-04-28
KR20150036064A (ko) 2015-04-07

Similar Documents

Publication Publication Date Title
MX360114B (es) Procedimiento de preparacion de 5-fluoro-1h-pirazoles.
CY1120188T1 (el) ΠΑΡΑΓΩΓΑ ΝΑΦΘΥΡΙΔΙΝΗΣ ΧΡΗΣΙΜΑ ΩΣ ΑΝΤΑΓΩΝΙΣΤΕΣ ΙΝΤΕΓΚΡΙΝΗΣ αvβ6
IN2014CN01136A (es)
MX2015002616A (es) Sintesis de bis(fluorosulfonil)imida.
EA200900945A1 (ru) Новый способ синтеза агомелатина
MX2018001731A (es) Un proceso novedoso para preparar n-[2-[[[1-(4-clorofenil)-1h-pira zol-3-il]oxi]metil]fenil]-n-metoxicarbamato de metilo cristalino.
EA200900946A1 (ru) Новый способ синтеза агомелатина
MX2018007106A (es) Metodo de produccion de un derivado de amida aromatica.
IN2014DN08840A (es)
MY169440A (en) Method of marking hydrocarbon liquids
MX2019004569A (es) Metodo para producir 3-alquilsulfanil-2-cloro-n-(1-alquil-1h-tetra zol-5-il)-4-trifluorometilbenzamidas.
AR090566A1 (es) Proceso para la produccion de inhibidores de crr
MX2015002419A (es) Procedimiento de descarboxilacion de derivados de acido 3,5-bis(haloalquil)-pirazol-4-carboxilico.
MX369470B (es) Medios y método para el tratamiento de tumores sólidos.
CY1121116T1 (el) Νεα μεθοδος για την συνθεση αγομελατινης
EA200900943A1 (ru) Новый способ синтеза агомелатина
AR088358A1 (es) Proceso de obtencion de acidos isoxazolil-metoxi-nicotinicos
MY170131A (en) Tracers and method of marking hydrocarbon liquids
TN2014000329A1 (en) Method for preparing compound by novel michael addition reaction using water or various acids as additive
PH12015501717A1 (en) Process for producing pyridazinone compound and production intermediates thereof
MX2013008595A (es) Procedimiento mejorado para la preparacion de 2,2-difluoroetilamina.
MX2015006828A (es) Procedimiento de preparacion de derivados de acido 4-haloalquil-3-mercapto-2 sustituido-hidroxibenzoico.
MX2015014728A (es) Sintesis de inhibidores de beta secretasa (bace).
EA201300794A1 (ru) Новый способ синтеза агомелатина
SA515360302B1 (ar) مركبات رباعي أكسا ثنائي فوسفا سبيرو

Legal Events

Date Code Title Description
FG Grant or registration
PD Change of proprietorship

Owner name: BAYER ANIMAL HEALTH GMBH