MX2010005811A - Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre. - Google Patents
Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre.Info
- Publication number
- MX2010005811A MX2010005811A MX2010005811A MX2010005811A MX2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A MX 2010005811 A MX2010005811 A MX 2010005811A
- Authority
- MX
- Mexico
- Prior art keywords
- melanoma cells
- blood
- circulating melanoma
- cells
- circulating
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70589—CD45
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
El CellTracks(r) System proporciona un sistema para enumerar las células del melanoma circulantes en la sangre. El sistema concentra inmunomagnéticamente células epiteliales, etiqueta de manera fluorescente las células e identifica y cuantifica las células del melanoma circulantes. La cantidad absoluta de células del melanoma circulantes detectadas en la carga tumoral de la sangre periférica es, en parte, un factor para la predicción de la supervivencia, tiempo de progreso y respuesta a la terapia. El diagnóstico y el control del melanoma se ha limitado por la incapacidad para observar las células del melanoma circulantes. La presente invención proporciona un método de enumerar las células del melanoma circulante en muestras de sangre. Por consiguiente, esta tecnología suministra un medio y un dispositivo para controlar el progreso de la enfermedad en pacientes con melanoma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US434507P | 2007-11-27 | 2007-11-27 | |
PCT/US2008/080436 WO2009070392A1 (en) | 2007-11-27 | 2008-10-20 | Automated enumeration and characterization of circulating melanoma cells in blood |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010005811A true MX2010005811A (es) | 2010-06-09 |
Family
ID=40670042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010005811A MX2010005811A (es) | 2007-11-27 | 2008-10-20 | Enumeracion automatica y caracterizacion de las celulas del melanoma circulantes en la sangre. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20090136946A1 (es) |
EP (1) | EP2225563B1 (es) |
JP (1) | JP5479355B2 (es) |
KR (1) | KR101604649B1 (es) |
CN (1) | CN101878429B (es) |
BR (1) | BRPI0819854B1 (es) |
CA (1) | CA2706442C (es) |
DK (1) | DK2225563T3 (es) |
HK (2) | HK1148068A1 (es) |
IL (1) | IL205864A (es) |
MX (1) | MX2010005811A (es) |
WO (1) | WO2009070392A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8710836B2 (en) | 2008-12-10 | 2014-04-29 | Nanomr, Inc. | NMR, instrumentation, and flow meter/controller continuously detecting MR signals, from continuously flowing sample material |
EP2446271A1 (en) * | 2009-06-26 | 2012-05-02 | Erasmus University Medical Center Rotterdam | Identifying circulating tumor cells (ctcs) using cd146 in breast cancers patients |
US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US8841104B2 (en) | 2010-04-21 | 2014-09-23 | Nanomr, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
US9428547B2 (en) | 2010-04-21 | 2016-08-30 | Dna Electronics, Inc. | Compositions for isolating a target analyte from a heterogeneous sample |
TWI539158B (zh) * | 2010-06-08 | 2016-06-21 | 維里德克斯有限責任公司 | 使用血液中之循環黑色素瘤細胞預測黑色素瘤病患之臨床結果的方法。 |
CN108375676B (zh) | 2011-07-21 | 2022-01-07 | 詹森诊断器材有限责任公司 | 从血液中捕获和检测循环多发性骨髓瘤的测定法 |
US9804069B2 (en) | 2012-12-19 | 2017-10-31 | Dnae Group Holdings Limited | Methods for degrading nucleic acid |
US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
US9434940B2 (en) | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
MX365713B (es) | 2013-03-15 | 2019-06-11 | Janssen Diagnostics Llc | Enriquecimiento de células tumorales circulantes por desgaste de glóbulos blancos. |
CN103472227A (zh) * | 2013-09-18 | 2013-12-25 | 上海卫恒医疗器械有限公司 | 一种循环肿瘤细胞检测试剂盒、配套仪器及应用 |
DK3304074T3 (da) | 2015-05-26 | 2020-01-27 | Creatv Microtech Inc | Anvendelse af mitotisk indeks for cirkulerende tumorceller i cancerstratificering og -diagnostik |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
DE19736691A1 (de) * | 1997-08-22 | 1999-02-25 | Michael Prof Dr Med Giesing | Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen |
ATE439137T1 (de) * | 1997-11-14 | 2009-08-15 | Gen Hospital Corp | Behandlung von hämatologischen störungen |
AU760560B2 (en) * | 1998-02-12 | 2003-05-15 | Board Of Regents, The University Of Texas System | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
US20010018192A1 (en) * | 1998-02-12 | 2001-08-30 | Terstappen Leon W.M.M. | Labeled cells for use as an internal functional control in rare cell detection assays |
US7029652B2 (en) * | 1998-09-16 | 2006-04-18 | The Regents Of The University Of California | Method of treating tumors |
US6551843B1 (en) * | 1999-01-29 | 2003-04-22 | Immunivest Corporation | Methods for enhancing binding interactions between members of specific binding pairs |
US6222096B1 (en) * | 1999-03-01 | 2001-04-24 | Stine Biotechnology | Promoter and construct for plant transformation |
US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
CA2378182C (en) * | 1999-07-28 | 2014-09-23 | Genentech, Inc. | Compositions and methods for the treatment of tumors |
DE60140865D1 (de) * | 2000-03-27 | 2010-02-04 | Univ Jefferson | Zusammensetzungen und methoden zur identifizierung von krebszellen |
CA2462758A1 (en) * | 2000-10-13 | 2002-04-18 | Monash University | Diagnostic indicator of thymic function |
US7223596B2 (en) * | 2003-09-05 | 2007-05-29 | Wisconsin Alumni Research Foundation | Malignant endothelial cell line and uses thereof in models for angiogenesis |
WO2006130737A1 (en) * | 2005-06-02 | 2006-12-07 | Immunivest Corporation | A method for assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells |
US20070037173A1 (en) * | 2005-08-12 | 2007-02-15 | Allard Jeffrey W | Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients |
-
2008
- 2008-10-20 WO PCT/US2008/080436 patent/WO2009070392A1/en active Application Filing
- 2008-10-20 KR KR1020107013842A patent/KR101604649B1/ko active IP Right Grant
- 2008-10-20 EP EP08855440.7A patent/EP2225563B1/en active Active
- 2008-10-20 BR BRPI0819854-3A patent/BRPI0819854B1/pt not_active IP Right Cessation
- 2008-10-20 JP JP2010536033A patent/JP5479355B2/ja not_active Expired - Fee Related
- 2008-10-20 DK DK08855440.7T patent/DK2225563T3/en active
- 2008-10-20 CN CN200880118137.XA patent/CN101878429B/zh active Active
- 2008-10-20 MX MX2010005811A patent/MX2010005811A/es active IP Right Grant
- 2008-10-20 US US12/254,188 patent/US20090136946A1/en not_active Abandoned
- 2008-10-20 CA CA2706442A patent/CA2706442C/en active Active
-
2010
- 2010-05-20 IL IL205864A patent/IL205864A/en active IP Right Grant
-
2011
- 2011-03-01 HK HK11102062.6A patent/HK1148068A1/xx unknown
- 2011-03-07 HK HK11102264.2A patent/HK1148348A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL205864A0 (en) | 2010-11-30 |
EP2225563A1 (en) | 2010-09-08 |
JP2011505012A (ja) | 2011-02-17 |
KR101604649B1 (ko) | 2016-03-18 |
BRPI0819854B1 (pt) | 2019-06-04 |
CA2706442A1 (en) | 2009-06-04 |
WO2009070392A1 (en) | 2009-06-04 |
KR20100101109A (ko) | 2010-09-16 |
US20090136946A1 (en) | 2009-05-28 |
CN101878429A (zh) | 2010-11-03 |
HK1148348A1 (en) | 2011-09-02 |
CN101878429B (zh) | 2015-05-20 |
DK2225563T3 (en) | 2015-02-09 |
IL205864A (en) | 2016-12-29 |
EP2225563B1 (en) | 2015-01-21 |
EP2225563A4 (en) | 2011-11-16 |
CA2706442C (en) | 2017-07-11 |
BRPI0819854A2 (pt) | 2015-06-16 |
HK1148068A1 (en) | 2011-08-26 |
JP5479355B2 (ja) | 2014-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |