MX2010005060A - Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados. - Google Patents

Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados.

Info

Publication number
MX2010005060A
MX2010005060A MX2010005060A MX2010005060A MX2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A MX 2010005060 A MX2010005060 A MX 2010005060A
Authority
MX
Mexico
Prior art keywords
mapping
dna microarray
based identification
translocation breakpoints
microarray based
Prior art date
Application number
MX2010005060A
Other languages
English (en)
Inventor
Harvey A Greisman
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of MX2010005060A publication Critical patent/MX2010005060A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

La presente invención prove métodos para detector y mapear re-arreglos cromosomales asociados con varias enfermedades usando hibridización genómica comparativa. Se incluyen métodos para identificar socios de translocación de sitios genómicos conocidos y para determinar puntos de ruptura de translocación. Los métodos de la presente invención pueden también ser usados en la prognosis, diagnosis y determinación de predisposición a enfermedades que involucran rearreglos cromosomales tales como translocaciones.
MX2010005060A 2007-11-08 2008-11-10 Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados. MX2010005060A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98657607P 2007-11-08 2007-11-08
PCT/US2008/083014 WO2009062166A2 (en) 2007-11-08 2008-11-10 Dna microarray based identification and mapping of balanced translocation breakpoints

Publications (1)

Publication Number Publication Date
MX2010005060A true MX2010005060A (es) 2010-07-05

Family

ID=40626471

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005060A MX2010005060A (es) 2007-11-08 2008-11-10 Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados.

Country Status (10)

Country Link
US (1) US20110021371A1 (es)
EP (1) EP2217921A4 (es)
JP (1) JP5421278B2 (es)
KR (1) KR20100097139A (es)
CN (1) CN101918831B (es)
AU (1) AU2008323649A1 (es)
BR (1) BRPI0820272A2 (es)
CA (1) CA2704625A1 (es)
MX (1) MX2010005060A (es)
WO (1) WO2009062166A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2147981A1 (en) * 2008-07-25 2010-01-27 Biotype AG Kit and method for evaluating detection properties in amplification reactions
ITMI20091007A1 (it) 2009-06-09 2010-12-10 Giovanni Porta Metodo di monitoraggio e trattamento
WO2011038360A1 (en) 2009-09-25 2011-03-31 Signature Genomics Laboratories Llc Multiplex (+/-) stranded arrays and assays for detecting chromosomal abnormalities associated with cancer and other diseases
WO2012159069A1 (en) * 2011-05-19 2012-11-22 University Of Utah Research Foundation Methods and compostions for the detection of balanced reciprocal translocations/rearrangements
WO2013033169A1 (en) * 2011-08-31 2013-03-07 Sanofi Methods of identifying genomic translocations associated with cancer
FR3010530B1 (fr) * 2013-09-11 2015-10-09 Univ Rouen Methode de diagnostic des hemopathies malignes et kit associe
CN103704205B (zh) * 2014-01-15 2015-09-23 山东大学 一种含微量稀土的牛***冷冻稀释液及其应用
US10443090B2 (en) 2014-11-25 2019-10-15 Electronics And Telecommunications Research Institute Method and apparatus for detecting translocation
US20180148773A1 (en) * 2015-05-29 2018-05-31 Altergon Sa Methods, supports and kits for enhanced cgh analysis
CN105044168A (zh) * 2015-06-03 2015-11-11 福建医科大学 基于氟代核酸探针的双通道传感器检测急早幼粒PML/RARα基因序列的方法
CN112669902B (zh) * 2021-03-16 2021-06-04 北京贝瑞和康生物技术有限公司 检测基因组结构变异的方法、计算设备和存储介质

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US6251601B1 (en) * 1999-02-02 2001-06-26 Vysis, Inc. Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays
CA2447320A1 (en) * 2001-05-14 2002-11-21 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish)
US20050159378A1 (en) * 2001-05-18 2005-07-21 Sirna Therapeutics, Inc. RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA)
US7198897B2 (en) * 2001-12-19 2007-04-03 Brandeis University Late-PCR
US20030124539A1 (en) * 2001-12-21 2003-07-03 Affymetrix, Inc. A Corporation Organized Under The Laws Of The State Of Delaware High throughput resequencing and variation detection using high density microarrays
US20040097711A1 (en) * 2002-03-12 2004-05-20 Henry Yue Immunoglobulin superfamily proteins
US20050112689A1 (en) * 2003-04-04 2005-05-26 Robert Kincaid Systems and methods for statistically analyzing apparent CGH data anomalies and plotting same
AU2003901671A0 (en) * 2003-04-02 2003-05-01 The University Of Adelaide Comparative genomic hybridization
DE102005028381A1 (de) * 2005-06-20 2006-12-28 Wella Ag Produktabgabesystem zum Versprühen haarkerantinreduzierende oder oxidierende Wirkstoffe enthaltender Zusammensetzungen
DE102005031734A1 (de) * 2005-07-07 2007-01-18 GM Global Technology Operations, Inc., Detroit Verfahren zur Berechnung des Unterdruckes im Bremskraftverstärker eines Fahrzeugs mit Otto-Motor
GB0516797D0 (en) * 2005-08-16 2005-09-21 Oxford Gene Tech Ip Ltd CGH method
US8076074B2 (en) * 2005-11-29 2011-12-13 Quest Diagnostics Investments Incorporated Balanced translocation in comparative hybridization
US8058055B2 (en) * 2006-04-07 2011-11-15 Agilent Technologies, Inc. High resolution chromosomal mapping

Also Published As

Publication number Publication date
CN101918831A (zh) 2010-12-15
EP2217921A4 (en) 2011-07-06
BRPI0820272A2 (pt) 2015-05-26
JP5421278B2 (ja) 2014-02-19
CA2704625A1 (en) 2009-05-14
JP2011505122A (ja) 2011-02-24
US20110021371A1 (en) 2011-01-27
CN101918831B (zh) 2014-10-15
KR20100097139A (ko) 2010-09-02
AU2008323649A1 (en) 2009-05-14
EP2217921A2 (en) 2010-08-18
WO2009062166A2 (en) 2009-05-14
WO2009062166A3 (en) 2009-12-30

Similar Documents

Publication Publication Date Title
MX2010005060A (es) Identificacion y mapeo a base de microarreglos de adn de puntos de ruptura de translocacion equilibrados.
Nejman et al. Molecular rules governing de novo methylation in cancer
WO2007146819A3 (en) Methods for identifying and using snp panels
EP1934377A4 (en) METHOD AND COMPOSITIONS FOR IDENTIFYING BIOMARKERS SUITED TO THE DIAGNOSIS AND / OR TREATMENT OF BIOLOGICAL CONDITIONS
WO2014116729A3 (en) Haplotying of hla loci with ultra-deep shotgun sequencing
WO2008146309A3 (en) Genetic variants on chr 5pl2 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
ATE432979T1 (de) Mutierte dna-polymerasen mit erhöhter fehlpaarungs-diskriminirung
WO2010056374A3 (en) Methods and compositions of molecular profiling for disease diagnostics
WO2009015863A3 (en) Methods of detecting methylated dna at a specific locus
WO2008117314A3 (en) Genetic variants on chr2 and chr16 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment
WO2013132074A3 (en) A genotyping test for assessing risk of autism
WO2008088893A3 (en) Gene polymorphisms in vegf and vegf receptor 2 as markers for cancer therapy
WO2008132763A3 (en) Genetic variants useful for risk assessment of coronary artery disease and myocardial infarction
WO2009097270A3 (en) Method of determining breast cancer risk
ATE446385T1 (de) Polymorphismen im nod2/card15 gen
Li et al. Identical but not the same: the value of DNA methylation profiling in forensic discrimination within monozygotic twins
Mossner et al. Skewed X-inactivation patterns in ageing healthy and myelodysplastic haematopoiesis determined by a pyrosequencing based transcriptional clonality assay
Sabeeha et al. Forensic epigenetic analysis: the path ahead
WO2008063655A3 (en) Dna methylation markers and methods of use
HK1096127A1 (en) Identifying chromosomal abnormalities in cells obtained from follicular fluid
WO2010007083A3 (en) Methods and nucleic acids for analyses of cell proliferative disorders
WO2008104985A3 (en) Methods for distingushing between lung squamous carcinoma and other non smallcell lung cancers
WO2008104984A3 (en) Diagnosis and prognosis of various types of cancers
MX2016012718A (es) Determinación de polimorfismos de un solo nucleótido útil para predecir la respuesta para rasagilina.
WO2008048902A3 (en) Methods of using single nucleotide polymorphisms in the il23r gene to predict or diagnose inflammatory bowel disease

Legal Events

Date Code Title Description
FA Abandonment or withdrawal