MX2010003109A - Acidos nucleicos de enlace c5a. - Google Patents

Acidos nucleicos de enlace c5a.

Info

Publication number
MX2010003109A
MX2010003109A MX2010003109A MX2010003109A MX2010003109A MX 2010003109 A MX2010003109 A MX 2010003109A MX 2010003109 A MX2010003109 A MX 2010003109A MX 2010003109 A MX2010003109 A MX 2010003109A MX 2010003109 A MX2010003109 A MX 2010003109A
Authority
MX
Mexico
Prior art keywords
nucleic acids
binding nucleic
type
nucleic
nucleic acid
Prior art date
Application number
MX2010003109A
Other languages
English (en)
Inventor
Sven Klussmann
Dirk Eulberg
Christian Maasch
Klaus Buchner
Florian Jarosch
Werner Purschke
Original Assignee
Noxxon Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noxxon Pharma Ag filed Critical Noxxon Pharma Ag
Publication of MX2010003109A publication Critical patent/MX2010003109A/es

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/323Chemical structure of the sugar modified ring structure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
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    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

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  • Microbiology (AREA)
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Abstract

La presente invenci?n se refiere a un ?cido nucleico, que enlaza preferentemente a C5a, seleccionado del grupo que consiste en ?cidos nucleicos tipo A, ?cidos nucleicos tipo B, ?cidos nucleicos tipo C, ?cidos nucleicos tipo D y ?cidos nucleicos que tienen una secuencia de ?cido nucleico de acuerdo con cualesquiera de las SEQ. KXNo. 73 a 79.
MX2010003109A 2007-09-24 2008-09-24 Acidos nucleicos de enlace c5a. MX2010003109A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07018750 2007-09-24
PCT/EP2008/008097 WO2009040113A2 (en) 2007-09-24 2008-09-24 C5a BINDING NUCLEIC ACIDS

Publications (1)

Publication Number Publication Date
MX2010003109A true MX2010003109A (es) 2010-04-01

Family

ID=40174751

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010003109A MX2010003109A (es) 2007-09-24 2008-09-24 Acidos nucleicos de enlace c5a.

Country Status (11)

Country Link
US (1) US8507456B2 (es)
EP (2) EP2562256A3 (es)
JP (1) JP5798320B2 (es)
KR (1) KR20100072185A (es)
CN (1) CN101809154A (es)
AU (1) AU2008303775A1 (es)
BR (1) BRPI0817260A2 (es)
CA (1) CA2700441A1 (es)
MX (1) MX2010003109A (es)
RU (1) RU2010116245A (es)
WO (1) WO2009040113A2 (es)

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WO2010108657A2 (en) * 2009-03-23 2010-09-30 Noxxon Pharma Ag C5a binding nucleic acids and the use thereof
WO2011038301A2 (en) * 2009-09-25 2011-03-31 Xoma Technology Ltd. Screening methods
SG194626A1 (en) * 2011-04-26 2013-12-30 Regado Biosciences Inc A method for manufacturing pegylated oligonucleotides
JP6265891B2 (ja) 2011-06-07 2018-01-24 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. ヌクレオチド配列データの提供
WO2013082458A1 (en) 2011-12-02 2013-06-06 The Regents Of The University Of California Reperfusion protection solution and uses thereof
MX362061B (es) 2012-01-10 2019-01-07 Noxxon Pharma Ag Ácidos nucleicos de enlace c5a nuevos.
EP3063317B1 (en) 2013-10-28 2020-06-03 DOTS Technology Corp. Allergen detection
US10238700B2 (en) 2014-01-02 2019-03-26 Genelux Corporation Oncolytic virus adjunct therapy with agents that increase virus infectivity
CN106860867A (zh) * 2017-02-23 2017-06-20 中山大学 己糖激酶2特异性抑制剂在急性中枢神经***损伤疾病中的应用
EP3553521A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Gingivitis diagnostic methods, uses and kits

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US6395888B1 (en) * 1996-02-01 2002-05-28 Gilead Sciences, Inc. High affinity nucleic acid ligands of complement system proteins
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
US6395029B1 (en) 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents
US6652886B2 (en) 2001-02-16 2003-11-25 Expression Genetics Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
EP1306382A1 (de) 2001-10-26 2003-05-02 Noxxon Pharma AG Modifizierte L-Nukleinsäure
AU2003219796A1 (en) 2002-02-20 2003-09-09 Beth Israel Deaconess Medical Center Conjugates comprising a biodegradable polymer and uses therefor
AU2004230927B9 (en) 2003-04-13 2011-12-01 Enzon Pharmaceuticals, Inc. Polymeric oligonucleotide prodrugs
GB0314472D0 (en) 2003-06-20 2003-07-23 Warwick Effect Polymers Ltd Polymer
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EP1713509A2 (de) 2004-02-09 2006-10-25 Noxxon Pharma AG Verfahren zur herstellung von konjugaten aus polysacchariden und polynukleotiden
DK2860251T3 (en) * 2004-02-12 2018-06-06 Archemix Llc APTAPMER PHARMACEUTICALS USEFUL IN TREATMENT OF COMPLEMENT-RELATED DISEASES
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JP5107716B2 (ja) 2004-11-05 2012-12-26 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 分子治療用生分解性リンカー
MX2008011323A (es) * 2006-03-08 2008-11-18 Archemix Corp Aptameros que se unen al complemento y agentes anti-c5 utiles en el tratamiento de trastornos oculares.
JP2010503707A (ja) 2006-09-15 2010-02-04 エンゾン ファーマスーティカルズ インコーポレイテッド オリゴヌクレオチドの送達を目的としたヒンダードエステル系生体分解性リンカー
WO2008052774A2 (en) 2006-10-31 2008-05-08 Noxxon Pharma Ag Methods for detection of a single- or double-stranded nucleic acid molecule
WO2010108657A2 (en) * 2009-03-23 2010-09-30 Noxxon Pharma Ag C5a binding nucleic acids and the use thereof

Also Published As

Publication number Publication date
CA2700441A1 (en) 2009-04-02
EP2205734A2 (en) 2010-07-14
RU2010116245A (ru) 2011-11-10
AU2008303775A1 (en) 2009-04-02
EP2562256A3 (en) 2013-06-19
WO2009040113A3 (en) 2009-06-11
WO2009040113A2 (en) 2009-04-02
BRPI0817260A2 (pt) 2014-10-14
JP5798320B2 (ja) 2015-10-21
KR20100072185A (ko) 2010-06-30
CN101809154A (zh) 2010-08-18
JP2010539893A (ja) 2010-12-24
US20110046207A1 (en) 2011-02-24
EP2562256A2 (en) 2013-02-27
US8507456B2 (en) 2013-08-13

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