MX2010000235A - Virus del sindrome respiratorio y reproductivo porcino tipo 1 norteamericano recombinante y metodos de uso. - Google Patents
Virus del sindrome respiratorio y reproductivo porcino tipo 1 norteamericano recombinante y metodos de uso.Info
- Publication number
- MX2010000235A MX2010000235A MX2010000235A MX2010000235A MX2010000235A MX 2010000235 A MX2010000235 A MX 2010000235A MX 2010000235 A MX2010000235 A MX 2010000235A MX 2010000235 A MX2010000235 A MX 2010000235A MX 2010000235 A MX2010000235 A MX 2010000235A
- Authority
- MX
- Mexico
- Prior art keywords
- north american
- american type
- respiratory syndrome
- prrsv
- porcine reproductive
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10041—Use of virus, viral particle or viral elements as a vector
- C12N2770/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10061—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
El virus de síndrome respiratorio y reproductivo de porcino (PRRSV) es un problema importante en la industria mundial de carne de puerco. La inclusión de marcadores en las vacunas permitirá la diferenciación de diagnóstico de animales vacunados de aquellos infectados naturalmente con virus de tipo natural. Usando un clon infeccioso de cADN de PRRSV Tipo 1 de Norteamérica, se ha hecho un PRRSV etiquetado de proteína fluorescente verde recombinante (GFP), que contiene la eliminación de un epítopo inmunogénico, ES4, en la región nsp2. Los ELISA basados en epítopo GFP y ES4 cumplen la identificación del marcador.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94608007P | 2007-06-25 | 2007-06-25 | |
PCT/US2008/068041 WO2009002981A1 (en) | 2007-06-25 | 2008-06-24 | Recombinant north american type 1 porcine reproductive and respiratory syndrome virus and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010000235A true MX2010000235A (es) | 2010-08-02 |
Family
ID=39811835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010000235A MX2010000235A (es) | 2007-06-25 | 2008-06-24 | Virus del sindrome respiratorio y reproductivo porcino tipo 1 norteamericano recombinante y metodos de uso. |
Country Status (11)
Country | Link |
---|---|
US (1) | US8182984B2 (es) |
EP (1) | EP2181189B1 (es) |
JP (1) | JP2010531143A (es) |
KR (1) | KR20100058451A (es) |
CN (1) | CN101848995A (es) |
CA (1) | CA2691755A1 (es) |
DK (1) | DK2181189T3 (es) |
ES (1) | ES2389748T3 (es) |
MX (1) | MX2010000235A (es) |
PL (1) | PL2181189T3 (es) |
WO (1) | WO2009002981A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2009001197A1 (es) * | 2009-05-15 | 2009-08-21 | Farm En Aquacultura Veterinaria Fav S A | Composicion farmaceutica veterinaria que contiene la variedad chilena del virus de la anemia infecciosa del salmon, marcadores proteicos y excipientes farmaceuticasmente aceptables; procedimiento de obtencion del virus; uso de la composicion para preparar una vacuna destinada a la prevencion del virus isa. |
CN102304496B (zh) * | 2010-02-05 | 2012-12-26 | 中国兽医药品监察所 | 高致病性猪繁殖与呼吸综合征病毒弱毒疫苗株GDr株的致弱培育 |
UA108902C2 (uk) * | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
JP2015533474A (ja) | 2012-07-18 | 2015-11-26 | サウス ダコタ ボード オブ リージェンツ | 新規なアルテリウイルスタンパク質および発現機構 |
US9457073B2 (en) * | 2012-09-26 | 2016-10-04 | University Of Manitoba | Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity |
CN103087996B (zh) * | 2013-01-18 | 2014-07-16 | 中国农业大学 | 重组猪繁殖与呼吸综合征病毒及其制备方法与应用 |
CN103773740B (zh) * | 2013-12-19 | 2016-08-17 | 广东省农业科学院动物卫生研究所 | 猪呼吸与繁殖综合征病毒复制缺陷性病毒疫苗株的构建及应用 |
US10010601B2 (en) | 2013-12-20 | 2018-07-03 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus variant, European PRRS virus cDNA clone, and uses thereof |
CN105603040A (zh) * | 2015-11-10 | 2016-05-25 | 环境保护部华南环境科学研究所 | 一种观察不同生理状态pc12细胞之间相互影响的方法 |
US10729756B2 (en) | 2017-05-30 | 2020-08-04 | The United States Of America, As Represented By The Secretary Of Agriculture | Viable viruses with foreign tags |
CN109554375A (zh) * | 2018-12-13 | 2019-04-02 | 郑州大学 | 美洲型prrsv n蛋白抗原表位及其应用 |
CN111996213A (zh) * | 2020-02-06 | 2020-11-27 | 广西大学 | 猪繁殖与呼吸综合征病毒双荧光标记基因重组毒株的构建方法 |
CN114778852B (zh) * | 2022-04-26 | 2023-09-01 | 中国农业大学 | 一种检测prrsv plp2抗体的间接elisa方法 |
CN116004551B (zh) * | 2022-09-19 | 2024-07-23 | 中国农业科学院上海兽医研究所 | 一种调节mhc-ii类反式激活因子ciita基因的猪繁殖与呼吸综合征病毒活疫苗的构建及其应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE144144T1 (de) | 1991-08-26 | 1996-11-15 | James Edward Collins | Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas) |
US6982160B2 (en) | 1991-08-26 | 2006-01-03 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions that include SIRS virus |
US6080570A (en) | 1991-08-26 | 2000-06-27 | Boehringer Ingelheim Vetmedica, Inc. | Method of producing a vaccine for Swine Infertility and Respiratory Syndrome |
CA2076744C (en) | 1991-08-26 | 2000-06-27 | Danny W. Chladek | Viral agent associated with mystery swine disease |
US5846805A (en) | 1991-08-26 | 1998-12-08 | Boehringer Ingelheim Animal Health, Inc. | Culture of swine infertility and respiratory syndrome virus in simian cells |
US5695766A (en) | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
KR100374295B1 (ko) | 1993-02-08 | 2003-12-24 | 바이엘 코포레이션 | 돼지생식및호흡증후군바이러스의생육방법과백신에서그의용도 |
ES2262142T3 (es) | 1994-08-05 | 2006-11-16 | Regents Of The University Of Minnesota | Secuencia virica de nucleotidos de vr-2332 y metodos de uso. |
US5690940A (en) | 1995-06-21 | 1997-11-25 | Regents Of The University Of Minnesota | Low pathogencity PRRS live virus vaccines and methods of preparation thereof |
EP0839912A1 (en) | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
US7691389B2 (en) * | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
US7132106B2 (en) | 1998-12-22 | 2006-11-07 | Pfizer Inc. | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
NZ501264A (en) | 1998-12-22 | 2001-09-28 | Pfizer Prod Inc | Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS |
CA2366072C (en) | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Prrsv vaccines |
PT2251419E (pt) * | 1999-04-22 | 2012-09-03 | Us Agriculture | Vacina contra a síndrome reprodutiva e respiratória porcina com base no isolado ja-142 |
ATE333500T1 (de) | 2000-02-08 | 2006-08-15 | Univ Minnesota | Virus des porzinen reproduktiven und respiratorischen syndroms und dessen verwendung |
US6841364B2 (en) | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
WO2007065151A2 (en) * | 2005-12-02 | 2007-06-07 | Iowa State University Research Foundation, Inc. | Differential immunoassay for prrs vaccine antibody |
-
2008
- 2008-06-24 EP EP08771834A patent/EP2181189B1/en not_active Not-in-force
- 2008-06-24 MX MX2010000235A patent/MX2010000235A/es not_active Application Discontinuation
- 2008-06-24 PL PL08771834T patent/PL2181189T3/pl unknown
- 2008-06-24 DK DK08771834.2T patent/DK2181189T3/da active
- 2008-06-24 ES ES08771834T patent/ES2389748T3/es active Active
- 2008-06-24 CA CA002691755A patent/CA2691755A1/en not_active Abandoned
- 2008-06-24 WO PCT/US2008/068041 patent/WO2009002981A1/en active Application Filing
- 2008-06-24 JP JP2010513497A patent/JP2010531143A/ja active Pending
- 2008-06-24 KR KR1020107001724A patent/KR20100058451A/ko not_active Application Discontinuation
- 2008-06-24 CN CN200880104270A patent/CN101848995A/zh active Pending
- 2008-06-24 US US12/145,231 patent/US8182984B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2010531143A (ja) | 2010-09-24 |
EP2181189B1 (en) | 2012-06-20 |
US20100136047A1 (en) | 2010-06-03 |
EP2181189A1 (en) | 2010-05-05 |
WO2009002981A1 (en) | 2008-12-31 |
DK2181189T3 (da) | 2012-09-24 |
PL2181189T3 (pl) | 2012-11-30 |
KR20100058451A (ko) | 2010-06-03 |
CN101848995A (zh) | 2010-09-29 |
CA2691755A1 (en) | 2008-12-31 |
US8182984B2 (en) | 2012-05-22 |
ES2389748T3 (es) | 2012-10-31 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |