MX2009013069A - Tratamiento de leucemia resistente al imatinib. - Google Patents

Tratamiento de leucemia resistente al imatinib.

Info

Publication number
MX2009013069A
MX2009013069A MX2009013069A MX2009013069A MX2009013069A MX 2009013069 A MX2009013069 A MX 2009013069A MX 2009013069 A MX2009013069 A MX 2009013069A MX 2009013069 A MX2009013069 A MX 2009013069A MX 2009013069 A MX2009013069 A MX 2009013069A
Authority
MX
Mexico
Prior art keywords
treatment
resistant leukemia
imatinib resistant
imatinib
leukemia
Prior art date
Application number
MX2009013069A
Other languages
English (en)
Inventor
Becker Hewes
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009013069(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of MX2009013069A publication Critical patent/MX2009013069A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invención proporciona compuestos 4-anilino-3-quinolina carbonitrilos útiles para tratar un sujeto que tiene una leucemia positiva BcrABl que es resistente al imatinib.
MX2009013069A 2007-06-01 2008-05-30 Tratamiento de leucemia resistente al imatinib. MX2009013069A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93265007P 2007-06-01 2007-06-01
PCT/US2008/065215 WO2008150957A2 (en) 2007-06-01 2008-05-30 Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles

Publications (1)

Publication Number Publication Date
MX2009013069A true MX2009013069A (es) 2010-03-17

Family

ID=39639071

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013069A MX2009013069A (es) 2007-06-01 2008-05-30 Tratamiento de leucemia resistente al imatinib.

Country Status (24)

Country Link
US (1) US11103497B2 (es)
EP (4) EP2478905B1 (es)
JP (3) JP5888853B2 (es)
KR (1) KR101493543B1 (es)
CN (1) CN101686973B (es)
AU (1) AU2008260070B9 (es)
BR (1) BRPI0812355A2 (es)
CA (3) CA2964162C (es)
CL (1) CL2008001577A1 (es)
CY (2) CY1115251T1 (es)
DK (2) DK3002009T3 (es)
ES (2) ES2477567T3 (es)
HK (1) HK1142812A1 (es)
HU (1) HUE055524T2 (es)
IL (1) IL202407A0 (es)
MX (1) MX2009013069A (es)
PA (1) PA8782301A1 (es)
PL (2) PL3002009T3 (es)
PT (2) PT3002009T (es)
RU (1) RU2464026C2 (es)
SI (2) SI2478905T1 (es)
TW (1) TW200908982A (es)
WO (1) WO2008150957A2 (es)
ZA (1) ZA200908480B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101686973B (zh) * 2007-06-01 2013-06-19 惠氏有限责任公司 应用4-氨基喹啉-3-腈治疗抗伊马替尼的白血病
EP2680844B1 (en) 2011-03-04 2016-10-19 GlaxoSmithKline Intellectual Property Development Limited Amino-quinolines as kinase inhibitors
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
TW201425307A (zh) 2012-09-13 2014-07-01 Glaxosmithkline Llc 作為激酶抑制劑之胺基－喹啉類
TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
RU2662810C2 (ru) 2013-02-21 2018-07-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Хиназолины в качестве ингибиторов киназы
KR101733665B1 (ko) * 2015-05-06 2017-05-10 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 진세노사이드 Ｆ1 또는 Ｒｇ3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
WO2021035101A1 (en) * 2019-08-22 2021-02-25 Biohaven Therapeutics Ltd. Molecules that bind to tdp-43 for the treatment of amyotrophic lateral sclerosis and related disorders
CN115944636A (zh) * 2022-11-01 2023-04-11 华南师范大学 博舒替尼在抑制i-motif结构上的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002008A (en) * 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6297258B1 (en) 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
IL156578A0 (en) * 2001-01-25 2004-01-04 Bristol Myers Squibb Co A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog
EP2343365A1 (en) 2001-10-05 2011-07-13 Novartis AG Mutated Abl kinase domains
TWI275390B (en) 2002-04-30 2007-03-11 Wyeth Corp Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) * 2003-07-09 2005-01-13 Kane John Richard Method and apparatus for providing access to personal information
WO2005046693A1 (en) 2003-11-06 2005-05-26 Wyeth 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (cml)
MX2007013217A (es) 2005-04-25 2008-03-11 Pfizer Anticuerpos contra miostatina.
PL1896470T3 (pl) 2005-05-16 2011-03-31 Irm Llc Pochodne pirolopirydynowe jako inhibitory kinazy białkowej
US20090163510A1 (en) 2005-07-15 2009-06-25 Bristol-Myers Squibb Company Methods of Identifying and Treating Individuals Exhibiting Mutant SRC Kinase Polypeptides
CN101277976B (zh) 2005-10-06 2012-04-11 伊莱利利公司 抗肌抑制素抗体
US20100029676A1 (en) 2005-11-04 2010-02-04 Sawyers Charles L T315a and f317i mutations of bcr-abl kinase domain
CN101686973B (zh) * 2007-06-01 2013-06-19 惠氏有限责任公司 应用4-氨基喹啉-3-腈治疗抗伊马替尼的白血病

Also Published As

Publication number Publication date
PA8782301A1 (es) 2009-01-23
ES2477567T3 (es) 2014-07-17
US11103497B2 (en) 2021-08-31
CL2008001577A1 (es) 2008-07-25
DK3002009T3 (da) 2021-08-02
ES2881391T3 (es) 2021-11-29
AU2008260070A1 (en) 2008-12-11
EP3002009B1 (en) 2021-07-07
EP2478905B1 (en) 2014-05-14
IL202407A0 (en) 2010-06-30
EP2152267A2 (en) 2010-02-17
EP2478905A2 (en) 2012-07-25
CY1115251T1 (el) 2017-01-04
BRPI0812355A2 (pt) 2015-01-27
CA2964162C (en) 2019-12-31
SI2478905T1 (sl) 2014-07-31
CA2688467C (en) 2015-05-12
CN101686973B (zh) 2013-06-19
RU2464026C2 (ru) 2012-10-20
AU2008260070B2 (en) 2011-08-18
CA2688467A1 (en) 2008-12-11
HUE055524T2 (hu) 2021-11-29
EP2478905A3 (en) 2013-01-16
CN101686973A (zh) 2010-03-31
KR101493543B1 (ko) 2015-02-13
PL3002009T3 (pl) 2021-12-13
WO2008150957A3 (en) 2009-08-06
WO2008150957A2 (en) 2008-12-11
KR20100017983A (ko) 2010-02-16
EP2777704A2 (en) 2014-09-17
RU2009144128A (ru) 2011-07-20
ZA200908480B (en) 2010-08-25
DK2478905T3 (da) 2014-06-30
AU2008260070B9 (en) 2012-01-19
JP2014111629A (ja) 2014-06-19
JP2016074700A (ja) 2016-05-12
JP5888853B2 (ja) 2016-03-22
PT3002009T (pt) 2021-08-02
EP3002009A3 (en) 2016-07-06
TW200908982A (en) 2009-03-01
US20080318971A1 (en) 2008-12-25
SI3002009T1 (sl) 2021-09-30
CY1124391T1 (el) 2022-07-22
CA2868899A1 (en) 2008-12-11
CA2868899C (en) 2017-06-13
PL2478905T3 (pl) 2014-10-31
JP2010529038A (ja) 2010-08-26
EP3002009A2 (en) 2016-04-06
EP2777704A3 (en) 2015-01-21
CA2964162A1 (en) 2008-12-11
PT2478905E (pt) 2014-07-16
HK1142812A1 (en) 2010-12-17

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