MX2009012228A - Compuesto de triazolil aminopirimidina. - Google Patents

Compuesto de triazolil aminopirimidina.

Info

Publication number
MX2009012228A
MX2009012228A MX2009012228A MX2009012228A MX2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A MX 2009012228 A MX2009012228 A MX 2009012228A
Authority
MX
Mexico
Prior art keywords
aminopyrimidine compounds
triazolyl
triazolyl aminopyrimidine
compounds
cancer
Prior art date
Application number
MX2009012228A
Other languages
English (en)
Inventor
Jason Scott Sawyer
James Robert Henry
Delu Jiang
Hong-Yu Li
Harold Burns Brooks
Joyce Z Crich
Melissa Kate Slater
Hong Hu
William Thomas Mcmillen
Yan Wang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2009012228A publication Critical patent/MX2009012228A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invención proporciona compuestos de triazolil aminopirimidina útiles en el tratamiento de cáncer.
MX2009012228A 2007-05-16 2008-05-07 Compuesto de triazolil aminopirimidina. MX2009012228A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93834707P 2007-05-16 2007-05-16
PCT/US2008/062808 WO2008144223A2 (en) 2007-05-16 2008-05-07 Triazolyl aminopyrimidine compounds

Publications (1)

Publication Number Publication Date
MX2009012228A true MX2009012228A (es) 2009-12-01

Family

ID=39951591

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012228A MX2009012228A (es) 2007-05-16 2008-05-07 Compuesto de triazolil aminopirimidina.

Country Status (15)

Country Link
US (1) US8063035B2 (es)
EP (1) EP2155734A2 (es)
JP (1) JP5248600B2 (es)
KR (1) KR101131261B1 (es)
CN (1) CN101679395B (es)
AR (1) AR066473A1 (es)
AU (1) AU2008254319B2 (es)
BR (1) BRPI0811433A2 (es)
CA (1) CA2691997A1 (es)
CL (1) CL2008001323A1 (es)
EA (1) EA016781B1 (es)
MX (1) MX2009012228A (es)
PE (1) PE20090216A1 (es)
TW (1) TW200908981A (es)
WO (1) WO2008144223A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964729B2 (en) 2006-08-28 2011-06-21 Massachusetts Institute Of Technology Sox-based kinase sensor
SI2125794T1 (sl) 2006-12-21 2011-02-28 Lilly Co Eli Spojine imidazolidinonil aminopirimidina za zdravljenje raka
MX2009006634A (es) 2006-12-21 2009-06-30 Lilly Co Eli Compuestos de imidazolidinonil aminopirimidina para el tratamiento de cancer.
US8440835B2 (en) 2007-02-26 2013-05-14 Massachusetts Institute Of Technology Environmentally sensitive fluorophores
AU2008254318B2 (en) 2007-05-16 2012-04-05 Eli Lilly And Company Triazolyl aminopyrimidine compounds
BRPI0811433A2 (pt) 2007-05-16 2016-03-22 Lilly Co Eli compostos do tipo triazolil aminopirimidina
KR101123178B1 (ko) * 2009-04-09 2012-06-13 (주)에스메디 2-아릴벤조싸이오펜 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 퇴행성 뇌질환의 진단 또는 치료용 약학적 조성물
CN102597236A (zh) * 2009-08-25 2012-07-18 肿瘤疗法科学股份有限公司 癌症治疗和诊断的靶基因ercc6l
US8409820B2 (en) 2009-08-31 2013-04-02 Massachusetts Institute Of Technology Kinase sensors
UA119247C2 (uk) 2013-09-06 2019-05-27 РОЙВЕНТ САЙЕНСИЗ ҐмбГ Спіроциклічні сполуки як інгібітори триптофангідроксилази
US9611201B2 (en) * 2015-03-05 2017-04-04 Karos Pharmaceuticals, Inc. Processes for preparing (R)-1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanone
JP7090037B2 (ja) * 2016-06-23 2022-06-23 エフ．ホフマン－ラ ロシュ アーゲー 新規な［１，２，３］トリアゾロ［４，５－ｄ］ピリミジン誘導体
WO2020068600A1 (en) * 2018-09-24 2020-04-02 Rapt Therapeutics, Inc. Ubiquitin-specific-processing protease 7 (usp7) modulators and uses thereof
US20220324770A1 (en) * 2019-09-05 2022-10-13 The University Of Melbourne Nitrification inhibitors
CN112341428A (zh) * 2020-11-04 2021-02-09 菏泽鸿特药业有限公司 一种噻吩-2-乙胺的生产方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929726A (en) * 1988-02-09 1990-05-29 Georgia State University Foundation, Inc. Novel diazines and their method of preparation
WO2004063192A1 (en) 2003-01-10 2004-07-29 Pharmacopeia Drug Discovery, Inc. Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators
GB0308466D0 (en) 2003-04-11 2003-05-21 Novartis Ag Organic compounds
JP2007533602A (ja) * 2003-07-31 2007-11-22 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 置換ベンゾチオフェン化合物及びそれらの使用
CA2590939C (en) 2004-12-17 2011-10-18 Amgen Inc. Aminopyrimidine compounds and methods of use
TW200800201A (en) 2005-11-18 2008-01-01 Lilly Co Eli Pyrimidinyl benzothiophene compounds
CN101437519A (zh) 2006-03-31 2009-05-20 艾博特公司 吲唑化合物
MX2009006634A (es) 2006-12-21 2009-06-30 Lilly Co Eli Compuestos de imidazolidinonil aminopirimidina para el tratamiento de cancer.
SI2125794T1 (sl) * 2006-12-21 2011-02-28 Lilly Co Eli Spojine imidazolidinonil aminopirimidina za zdravljenje raka
AU2008254318B2 (en) * 2007-05-16 2012-04-05 Eli Lilly And Company Triazolyl aminopyrimidine compounds
BRPI0811433A2 (pt) 2007-05-16 2016-03-22 Lilly Co Eli compostos do tipo triazolil aminopirimidina

Also Published As

Publication number Publication date
WO2008144223A3 (en) 2009-02-05
CL2008001323A1 (es) 2009-05-29
AU2008254319A1 (en) 2008-11-27
CN101679395A (zh) 2010-03-24
PE20090216A1 (es) 2009-02-28
KR101131261B1 (ko) 2012-04-24
US8063035B2 (en) 2011-11-22
JP2010527365A (ja) 2010-08-12
CN101679395B (zh) 2012-06-13
EA200971068A1 (ru) 2010-04-30
AR066473A1 (es) 2009-08-19
BRPI0811433A2 (pt) 2016-03-22
AU2008254319B2 (en) 2012-04-19
JP5248600B2 (ja) 2013-07-31
CA2691997A1 (en) 2008-11-27
KR20090130242A (ko) 2009-12-21
WO2008144223A2 (en) 2008-11-27
EP2155734A2 (en) 2010-02-24
EA016781B1 (ru) 2012-07-30
TW200908981A (en) 2009-03-01
US20100087431A1 (en) 2010-04-08

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